Channel:  Aligning Science Across Parkinson's (ASAP)

521 Articles

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JIP4 deficiency causes a novel lysosome storage disease arising from impaired cystine efflux
Nassar, L. M., Shi, x., Roczniak-Ferguson, A., Shen, H., Ferguson, S. M.
10.1101/2025.06.06.657909 — Posted: 2025-06-09
Genetic modulation of immune gene co-expression in the aged mouse hippocampus by the Apbb1ip locus
Tomkins, J. E., Methi, A., Bouland, G., Doludda, B., Murphy, K., Miller, J. A., Overall, R. W., Mozhui, K.
10.1101/2025.06.04.657838 — Posted: 2025-06-08
Parkinson's disease-vulnerable and -resilient dopamine neurons display opposite responses to excitatory input
Hadjas, L. C., Kollman, G. J., Linderhof, L., Xia, M., Mansur, S., Saint-Pierre, M., Lim, B., Lee, E. B., Cicchetti, F., Awatramani, R., Hollon, N. G., Hnasko, T. S.
10.1101/2025.06.03.657460 — Posted: 2025-06-07
Bridging Pleiotropic Mechanisms in Leprosy Type-1 Reactions and Neurodegenerative diseases
Fava, V. M., Perico, J., Orlova, M., Dallmann-Sauer, M., Xu, Y. Z., Van Thuc, N., Thai, V. H., Belone, A. F., Latini, A. C. P., Schurr, E.
10.1101/2025.06.05.25329059 — Posted: 2025-06-06
RAB32-linked Parkinson's disease: Deep phenotyping, MDSGene literature review, and application of SynNeurGe criteria
Kleinz, T., Cavallieri, F., Borsche, M., Toschi, G., Valzania, F., Fioravanti, V., Valente, E. M., Mitrotti, P., Avenali, M., Zittel, S., Born, R., Matarazzo, M., Di Fonzo, A., Monfrini, E., Radefeldt, M., Santinelli, L., Griebner, N., Shambetova, C., Brand, M., Gabbert, C., Blauwendraat, C., Trinh, J., Beetz, C., Bauer, P., Brueggemann, N., Global Parkinson's Genetics Program (GP2), , Klein, C.
10.1101/2025.06.03.25328628 — Posted: 2025-06-03
Genetically Encoded and Modular SubCellular Organelle Probes (GEM-SCOPe) reveal lysosomal and mitochondrial dysfunction driven by PRKN knockout
Goldman, C., Kareva, T., Sarrafha, L., Sahasrabudhe, A., Schuldt, B. R., Ahfeldt, T., Blanchard, J. W.
10.1101/2024.05.21.594886 — Posted: 2025-06-02
Movement-related activity in the internal globus pallidus of the parkinsonian macaque
Kase, D., Zimnik, A. J., Han, Y., Harsch, D. R., Bacha, S., Cox, K. M., Bostan, A. C., Richardson, R. M., Turner, R. S.
10.1101/2024.08.29.610310 — Posted: 2025-05-30
Sex-dimorphic effects of neuromelanin buildup in rodent nigral dopamine neurons: implications for sex-biased vulnerability in Parkinson's disease
D'Addario, S. L., Massaro Cenere, M., Cossa, F., Scaricamazza, S., Nesci, V., D'Ottavio, G., Caprioli, D., Ferri, A., Vila, M., Ledonne, A., Mercuri, N. B.
10.1101/2025.04.18.649338 — Posted: 2025-05-27
Genome-wide assessment identifies novel runs of homozygosity linked to Parkinson's disease etiology across diverse ancestral populations
Step, K., Hernandez, C. F., Eltaraifee, E., Hernandez-Medrano, A. J., Kung, P.-J., Ostrozovicova, M., Zirra, A., Perez-Palma, E., Mencacci, N. E., Keller Sarmiento, I. J., Morris, H., Mata, I., Global Parkinson's Genetics Program, , Acosta-Uribe, J., Fang, Z.-H., Bandres Ciga, S.
10.1101/2025.05.21.25328076 — Posted: 2025-05-22
Drug Repurposing for Parkinson's Disease: A Large-Scale Multi-Cohort Study
Hu, Y., Liu, W., Waits, M., Zhao, Y., Olivero-Acosta, M. I., Zhang, L., Scherzer, C. R., Dong, X.
10.1101/2025.05.20.25327943 — Posted: 2025-05-21

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