Channel:  Aligning Science Across Parkinson's (ASAP)

463 Articles

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The pyrethroid insecticide deltamethrin disrupts neuropeptide and monoamine signaling pathways in the gastrointestinal tract
White, A. C., Krout, I. N., Mouhi, S., Chang, J., Kelly, S. D., Caudle, W. M., Sampson, T.
10.1101/2024.12.14.628386 — Posted: 2024-12-17
Parkinson's Disease Pathogenic Variants: Cross-Ancestry Analysis and Microarray Data Validation
Hong, S., Koretsky, M. J., Lichtenberge, J., Leonard, H., Pitz, V., Global Parkinson's Genetics Program (GP2)
10.1101/2024.12.16.24319097 — Posted: 2024-12-17
Severe GBA1 variants drive the GBA-PD clinical phenotype: implications for counselling and clinical trials
Menozzi, E., Lucas Del Pozo, S., Macnaughtan, J., Mezabrovschi, R., Koletsi, S., Mitrotti, P., Gallo, L., Calabrese, R., Toffoli, M., Loefflad, N., Valzania, F., Cavallieri, F., Fioravanti, V., Yalkic, S., Limbachiya, N., Blandini, F., Avenali, M., Schapira, A. H.
10.1101/2024.12.09.24318560 — Posted: 2024-12-16
Exploring the relationship between GBA1 host genotype and gut microbiome in the GBA1L444P/WT mouse model: Implications for Parkinson disease pathogenesis
Menozzi, E., Geiger, M., Meslier, V., Fierli, F., Gilles, M., Chau, K.-Y., David, A., Shahar Golan, R., Famechon, A., Koletsi, S., Morabito, C., Quinquis, B., Pons, N., Ehrlich, S. D., Macnaughtan, J., Almeida, M., Schapira, A. H.
10.1101/2024.12.15.627490 — Posted: 2024-12-15
Impact of dopamine deficiency and REM sleep behavior disorder on cognition in early neuronal synuclein disease with hyposmia
Weintraub, D., Nair, A. R., Kurth, R., Brumm, M. C., York, M. K., Dobkin, R., Marek, K., Tanner, C. M., Simuni, T., Siderowf, A., Galsko, D., Chahine, L. M., Coffey, C., Merchant, K., Poston, K. L., Foroud, T., Mollenhauer, B., Brown, E. G., Kieburtz, K., Frasier, M., Sherer, T., Chowdhury, S., Alcalay, R. N., Videnovic, A., on behalf of the Parkinsons Progression Markers Initiative
10.1101/2024.12.12.24318917 — Posted: 2024-12-13
Smell testing to identify early alpha-synucleinopathy among people with dream enactment behavior
Brown, E., Chahine, L. M., Videnovic, A., Marshall, M. J., Kurth, R., Caspell-Garcia, C., Brumm, M. C., Coffey, C., Siderowf, A., Simuni, T., Marek, K., Tanner, C. M., on behalf of the Parkinsons Progression Markers Initiative
10.1101/2024.12.11.24318857 — Posted: 2024-12-12
LRRK2 G2019S mutation incites increased cell-intrinsic neutrophil effector functions and intestinal inflammation in a model of infectious colitis
Pei, J., Oliveira, N. L., Recinto, S. J., Kazanova, A., Queiroz-Junior, C. M., Li, Z., Couto, K., Westfall, S., King, I. L., Ribeiro, C. T., Milnerwood, A., Desjardins, M., Thanabalasuriar, A., STRATTON, J. A., Gruenheid, S.
10.1101/2024.11.26.625468 — Posted: 2024-12-02
Ancestry-specific gene expression in peripheral monocytes mediates risk of neurodegenerative disease
Wagen, A. Z., Reynolds, R. H., Nee Foo, J., Fairbrother-Browne, A., Gustavsson, E. K., Gagliano-Turin, S. A., Wood, N. W., Blauwendraat, C. K., Gandhi, S., Ryten, M.
10.1101/2024.11.20.624489 — Posted: 2024-11-22
Dopamine and cortical iPSC-derived neurons with different Parkinsonian mutations show variation in lysosomal and mitochondrial dysfunction: implications for protein deposition versus selective cell loss
Chedid, J., Li, Y., Labrador-Garrido, A., Abu-Bonsrah, D., Pavan, C., Fraser, T., Ovchinnikov, D., Zhong, M., Davis, R., Strbenac, D., Johnston, J. A., Thompson, L. H., Kirik, D., Parish, C., Halliday, G., Sue, C., Wali, G., Dzamko, N.
10.1101/2024.10.07.617117 — Posted: 2024-11-11
Single cell long read whole genome sequencing reveals somatic transposon activity in human brain
Izydorczyk, M. B., Kalef-Ezra, E., Horner, D., Zheng, X., Holmes, N., Toffoli, M., Sahin, Z. G., Han, Y., Mehta, H. H., Muzny, D. M., Ameur, A., Sedlazeck, F. J., Proukakis, C.
10.1101/2024.11.11.24317113 — Posted: 2024-11-11

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