Channel:  Aligning Science Across Parkinson's (ASAP)

456 Articles

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GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes
Sivadasan Bindu, D., Savage, J. T., Brose, N., Bradley, L., Dimond, K., Tan, C. X., Eroglu, C.
10.1101/2023.01.17.524433 — Posted: 2024-10-11
Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
Chen, M., Nguyen, T. N., Ren, X., Khuu, G., Cook, A. S. I., Zhao, Y., Yildiz, A., Lazarou, M., Hurley, J. H.
10.1101/2023.06.01.543278 — Posted: 2024-10-03
Endo-IP and Lyso-IP Toolkit for Endolysosomal Profiling of Human Induced Neurons
Hundley, F. V., Gonzalez-Lozano, M., Gottschalk, L. M., Cook, A. N. K., Zhang, J., Paulo, J. A., Harper, J. W.
10.1101/2024.09.24.614704 — Posted: 2024-09-26
Dissociation of putative open loop circuit from ventral putamen to motor cortical areas in humans I: high-resolution connectomics
Rizor, E. J., Dundon, N. M., Wang, J., Stasiak, J., Li, T., Bostan, A., Lapate, R. C., Grafton, S. T.
10.1101/2024.08.28.610129 — Posted: 2024-09-23
Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses
Mendelsohn, A., Nikoobakht, L., Bikoff, J., Costa, R.
10.1101/2024.08.28.610136 — Posted: 2024-09-18
A STING-CASM-GABARAP Pathway Activates LRRK2 at Lysosomes
Bentley-DeSousa, A., Roczniak-Ferguson, A., Ferguson, S. M.
10.1101/2023.10.31.564602 — Posted: 2024-09-11
Parkinson's Families Project: a UK-wide study of early onset and familial Parkinson's disease
Towns, C., Fang, Z.-H., Tan, M. M. X., Jasaityte, S., Schmaderer, T. M., Stafford, E. J., Pollard, M., Tilney, R., Hodgson, M., Wu, L., Labrum, R., Hehir, J., Polke, J., Lange, L. M., Schapira, A. H. V., Bhatia, K. P., Parkinsons Families Project (PFP) Study Group, , Global Parkinsons Genetics Program (GP2), , Singleton, A., Blauwendraat, C., Klein, C., Houlden, H., Wood, N. W., Jarman, P. R., Morris, H. R., Real, R.
10.1101/2023.12.05.23299397 — Posted: 2024-09-10
Neuronal alpha-Synuclein Disease Integrated Staging System performance in PPMI, PASADENA, and SPARK baseline cohorts.
Dam, T., Pagano, G., Brumm, M. C., Gochanour, C., Poston, K. L., Weintraub, D., Chahine, L. M., Coffey, C. S., Tanner, C. M., Kopil, C. M., Xiao, Y., Chowdhury, S., Concha-Marambio, L., DiBiaso, P., Foroud, T., Frasier, M., Jennings, D., Kieburtz, K., Merchant, K., Mollenhauer, B., Montine, T. J., Nudelman, K., Seibyl, J., Sherer, T., Singleton, A., Stephenson, D., Stern, M., Soto, C., Tolosa, E., Siderowf, A., Dunn, B., Simuni, T., Marek, K., and the Parkinson's Progression Markers Initiative
10.1101/2024.02.14.24302818 — Posted: 2024-09-10
Presynapses are mitophagy pit stops that prevent axon degeneration
Lam, W. K., Lindblom, R. S. J., Milky, B., Mazzachi, P., Hadian-Jazi, M., Kung, C., Khuu, G., Uoselis, L., Nguyen, T. N., Skulsuppaisarn, M., Saunders, T. L., Schmidt, M. F., Dewson, G., Fogel, A. I., Bardy, C., Lazarou, M.
10.1101/2024.09.09.611943 — Posted: 2024-09-09
The mitochondrial unfolded protein response promotes senescence in human microglia by increasing S-adenosylmethionine availability for polyamine synthesis.
Perez Jimenez, M. J., Bertoli, F., Raji, H., Lam, A., Bosch, M., Weissleder, C., Nemazanyy, I., Kalb, S., Hirschberg, I., Brunetti, D., Heckenbach, I., Scheibye-Knudsen, M., Deleidi, M.
10.1101/2024.09.03.610925 — Posted: 2024-09-03

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