Channel:  Aligning Science Across Parkinson's (ASAP)

403 Articles

The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4
Feringa, F. M., Koppes-den Hertog, S. J., Wang, L., Derks, R. J. E., Kruijff, I., Erlebach, L., Heijneman, J., Miramontes, R., Pömpner, N., Blomberg, N., Olivier-Jimenez, D., Johanson, L. E., Cammack, A. J., Giblin, A., Toomey, C. E., Rose, I. V. L., Yuan, H., Ward, M. E., Isaacs, A., Kampmann, M., Kronenberg-Versteeg, D., Lashley, T., Thompson, L. M., Ori, A., Mohammed, Y., Giera, M., van der Kant, R. H. N.
10.1101/2024.07.01.601474 — Posted: 2024-07-03
Functional efficacy of the MAO-B inhibitor safinamide in murine substantia nigra pars compacta dopaminergic neurons in vitro: a comparative study with tranylcypromine
Zarrilli, B., Giacomet, C., Cossa, F., Federici, M., Berretta, N., Mercuri, N. B.
10.1101/2024.05.28.596142 — Posted: 2024-06-26
Pathogenic LRRK2 mutations cause loss of primary cilia and Neurturin in striatal Parvalbumin interneurons
Lin, Y.-E., Jaimon, E., Tonelli, F., Pfeffer, S. R.
10.1101/2024.06.17.599289 — Posted: 2024-06-25
Presynaptic GABAA receptors control integration of nicotinic input onto dopaminergic axons in the striatum
Brill-Weil, S. G., Kramer, P. F., Yanez, A., Clever, F. H., Zhang, R., Khaliq, Z. M.
10.1101/2024.06.25.600616 — Posted: 2024-06-25
Decreased cellular excitability of pyramidal tract neurons in primary motor cortex leads to paradoxically increased network activity in simulated parkinsonian motor cortex
Doherty, D. W., Chen, L., Smith, Y., Wichmann, T., Chu, H.-y., Lytton, W. W.
10.1101/2024.05.23.595566 — Posted: 2024-06-23
Dissociation of novel open loop from ventral putamen to motor areas from classic closed loop in humans II: task-based function
Dundon, N. M., Rizor, E., Stasiak, J., Wang, J., Sabugo, K., Villaneuva, C., Barandon, P., Bostan, A. C., Lapate, R. C., Grafton, S. T.
10.1101/2024.06.18.599622 — Posted: 2024-06-22
Transcriptional pathobiology and multi-omics predictors for Parkinson's disease
Hu, R., Wang, R., Yuan, J., Lin, Z., Hutchins, E., Landin, B., Liao, Z., Liu, G., Scherzer, C. R., Dong, X.
10.1101/2024.06.18.599639 — Posted: 2024-06-21
Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2
Chen, S., Basiashvili, T., Hutchings, J., Murillo, M. S., Suarez, A. V., Louro, J. A., Leschziner, A. E., Villa, E.
10.1101/2024.06.18.599606 — Posted: 2024-06-20
Network nature of ligand-receptor interactions underlies disease comorbidity in the brain
Grant-Peters, M., Fairbrother-Browne, A., Hicks, A., Guo, B., Reynolds, R. H., Huuki-Myers, L. A., Eagles, N., Brenton, J., Garcia-Ruiz, S., Wood, N., Gandhi, S., Martinowich, K., Maynard, K., Collado-Torres, L., Ryten, M.
10.1101/2024.06.15.599140 — Posted: 2024-06-16
Mitochondrial oxidant stress promotes alpha-synuclein aggregation and spreading in mice with mutated glucocerebrosidase
La Vitola, P., Szego, E. M., Pinto-Costa, R., Rollar, A., Harbachova, E., Schapira, A. H. V., Ulusoy, A., Di Monte, D. A.
10.1101/2024.06.13.598820 — Posted: 2024-06-13

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