Channel:  Francis Crick Institute

1,336 Articles

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GROQ-seq Datasets Across Transcription Factors (LacI, RamR, VanR), T7 RNA Polymerase and TEV Protease
Spinner, A., Sreenivasan, S., McLellan, J. R., Ikonomova, S. P., Cortade, D. L., dOelsnitz, S., Sheldon, K., Vasilyeva, O. B., Alperovich, N. Y., Chadha, A., Nematollahi, L., Dhroso, A., Sisson, Z., Densmore, D., Hudson, C. M., DeBenedictis, E., Kelly, P. J., Reider Apel, A., Ross, D., Baranowski, C.
10.64898/2026.04.15.718744 — Posted: 2026-05-29
CDKL5 phosphorylates neuronal ELAVL proteins to promote mRNA binding, protein synthesis and visual cortex development
Mihaylov, S. R., Lopes, A. T., Silvestre, M., Bianchini, G., Flynn, H. R., Huseynova, A., Strohbuecker, S., Griffith, L., Militti, C., Baltussen, L. L., Yuan, X., Morel, G., Claxton, S., Dempster, K., Lee, F. C. Y., Kanca, O., Köhn, M., Skehel, M., Ule, J., Iacaruso, F., Ultanir, S. K.
10.64898/2026.04.07.716766 — Posted: 2026-05-29
Lineage-specific retrotransposon co-option reveals a conserved ASH2L isoform as an epigenetic primer of developmental gene promoters
Elgood Hunt, E., Vivori, C., Mitter, R., Hannah Johnkingsly Jebaraj, J., Agnadottir, V., Delas, J., Serna Morales, E., Frith, T., Skehel, M., Elosegui-Artola, A., Briscoe, J., van Werven, F.
10.64898/2026.02.25.707914 — Posted: 2026-05-27
Endolysosomal damage promotes intraluminal protein condensate formation that limits cytosolic leakage
LI, X., Zhang, Y., ZHAO, K., Chen, G., Cui, D., Nikan, M., Young, S., Bennett, F., Seth, P. P., Ni, T., Gutierrez, M. G., Jiang, H.
10.64898/2026.05.25.726725 — Posted: 2026-05-25
Asymmetric Contrastive Objectives for Efficient Phenotypic Screening
Nightingale, L., Tuersley, J., Warchal, S., Cairoli, A., Howes, J., Shand, C., Powell, A., Green, D., Strange, A., Howell, M.
10.1101/2024.04.19.590313 — Posted: 2026-05-22
A long-chain heparan sulfate capture mechanism directs paracrine GDNF-GFRα1 signalling through RET
Zol-Hanlon, M. I., Rix, B., Bodet-Lefevre, S., Zamora Porras, M., Briggs, D. C., Nans, A., Borg, A. C., Maslen, S. L., Di Maio, A., Feizi, T., Liu, Y., Chopra, P., Boons, G.-J. P., Pavljuk, J., Richter, R. P., Schumann, B., McDonald, N. Q.
10.64898/2026.05.20.726209 — Posted: 2026-05-21
Discovery of a sulfotyrosine-motif in the human TrkB extracellular domain required for agonist activation
Briggs, D. C., Duffy, R. T., Ateaque, S., Maslen, S., Naharaj, H., Barde, Y.-A., DiStefano, P. S., Lindsay, R. M., Armstrong, P. C., Peach, C. J., McDonald, N. Q.
10.64898/2026.05.19.725324 — Posted: 2026-05-21
Blocking mechanical airway epithelia damage during asthma progression reverses airway remodelling and hyperresponsiveness
Bagley, D. C., Russell, T., Martinez-Nunez, R. T., Marcotti, S., Rosenblatt, J.
10.1101/2025.11.10.687569 — Posted: 2026-05-17
Structure of the Pre-Initiation Complex Explains CMGE Biogenesis
Pühringer, T., Canal, B., Palm, G., Butryn, A., Couves, E. C., Willhoft, O., Lewis, J. S., Diffley, J. F. X., Costa, A.
10.64898/2026.05.15.725318 — Posted: 2026-05-17
Gene function and expression profiling in yeast spores, killifish diapause embryos, and their post-dormant offspring cells
Hassan, S., Rodriguez-Lopez, M., Townsend, S., Koksal, B., Akkus, S., Ori, A., Cellerino, A., Ralser, M., Bahler, J.
10.64898/2026.05.08.723705 — Posted: 2026-05-17

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