Channel:  Francis Crick Institute

1,288 Articles

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Asymmetric Contrastive Objectives for Efficient Phenotypic Screening
Nightingale, L., Tuersley, J., Warchal, S., Cairoli, A., Howes, J., Shand, C., Powell, A., Green, D., Strange, A., Howell, M.
10.1101/2024.04.19.590313 — Posted: 2026-05-22
A long-chain heparan sulfate capture mechanism directs paracrine GDNF-GFRα1 signalling through RET
Zol-Hanlon, M. I., Rix, B., Bodet-Lefevre, S., Zamora Porras, M., Briggs, D. C., Nans, A., Borg, A. C., Maslen, S. L., Di Maio, A., Feizi, T., Liu, Y., Chopra, P., Boons, G.-J. P., Pavljuk, J., Richter, R. P., Schumann, B., McDonald, N. Q.
10.64898/2026.05.20.726209 — Posted: 2026-05-21
Discovery of a sulfotyrosine-motif in the human TrkB extracellular domain required for agonist activation
Briggs, D. C., Duffy, R. T., Ateaque, S., Maslen, S., Naharaj, H., Barde, Y.-A., DiStefano, P. S., Lindsay, R. M., Armstrong, P. C., Peach, C. J., McDonald, N. Q.
10.64898/2026.05.19.725324 — Posted: 2026-05-21
Blocking mechanical airway epithelia damage during asthma progression reverses airway remodelling and hyperresponsiveness
Bagley, D. C., Russell, T., Martinez-Nunez, R. T., Marcotti, S., Rosenblatt, J.
10.1101/2025.11.10.687569 — Posted: 2026-05-17
Structure of the Pre-Initiation Complex Explains CMGE Biogenesis
Pühringer, T., Canal, B., Palm, G., Butryn, A., Couves, E. C., Willhoft, O., Lewis, J. S., Diffley, J. F. X., Costa, A.
10.64898/2026.05.15.725318 — Posted: 2026-05-17
Gene function and expression profiling in yeast spores, killifish diapause embryos, and their post-dormant offspring cells
Hassan, S., Rodriguez-Lopez, M., Townsend, S., Koksal, B., Akkus, S., Ori, A., Cellerino, A., Ralser, M., Bahler, J.
10.64898/2026.05.08.723705 — Posted: 2026-05-17
Mcm10 braces converging replicative helicases to pull apart origin DNA
Palm, G., Butryn, A., Canal, B., Pühringer, T., Gross, M. H., Diffley, J. F. X., Costa, A.
10.64898/2026.05.15.725099 — Posted: 2026-05-16
H3K27M-driven hypertranscription leads to a new targetable dependency in diffuse midline gliomas
PAL, S., Wang, H., Geisberg, J., Mirza, T., Kohli, K., Nazaretian, A., Knowles, T., Graser, C. J., Bootz, K., Wojcikowska, O., Bartynska, M., Boulton, S. J., Majithiya, J. B., Robinson, H., Smith, G., Stiles, C., Chowdhury, D., Agar, N. Y. R., Mueller, S., Michor, F., Haas-Kogan, D.
10.64898/2026.05.12.724628 — Posted: 2026-05-15
Decorrelation by gain control in the mouse olfactory bulb
Tootoonian, S., Yang, Y., Schaefer, A. T., Ackels, T.
10.64898/2026.05.07.722633 — Posted: 2026-05-11
Entropy Sorting Feature Selection: information-theoretic gene set identification improves single-cell RNA sequencing data interpretability
Radley, A., Boezio, G., Shand, C., Perez-Carrasco, R., Briscoe, J.
10.64898/2026.01.26.701684 — Posted: 2026-05-10

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