Channel:  Francis Crick Institute

1,225 Articles

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PKN2 regulates cell-junctions to limit colitis and colon tumour formation
Henry, J. C., Campbell, A. N., Huddar, P., Sewell, J., Menezes, S., Passman, A., Smith, K., McGauran, S., Lin, M.-L., Rosewell, I., Jansen, M., McDonald, N. Q., Graham, T. A., McDonald, S. A., Cameron, A. J.
10.64898/2025.12.15.694339 — Posted: 2025-12-17
Control of cellular cortical tension and shape by RhoGTPase signalling
Bohec, P., Khoromskaia, D., Kelkar, M., Ferber, E., Duprez, G., Lavoie, G., Valon, L., Roux, P. P., Salbreux, G., Charras, G.
10.64898/2025.12.15.694413 — Posted: 2025-12-17
Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data
Fontaine, M., Vives, M. J. D., Saez, M., Maizels, R., Finnie, E., Briscoe, J., Rand, D. A.
10.1101/2025.05.28.656648 — Posted: 2025-12-16
PD-L2 Regulates Natural Antibody and IL-10 Secretion by B-1 cells
Amendt, T., Vanes, L., Tybulewicz, V.
10.64898/2025.12.11.693708 — Posted: 2025-12-14
Advanced human iPSC-based modelling of LMNA-related congenital muscular dystrophy enables development of targeted genetic therapies for muscle laminopathies
Moore, D. P., Steele-Stallard, H. B., Pinton, L., Lionello, V. M., Rossi, L., Aghaeipour, A., Jalal, S., Wong, C. T. Y., Clara-Hwang, A., Bonne, G., Zammit, P. S., Tedesco, F. S.
10.1101/2025.06.22.660928 — Posted: 2025-12-13
Tracking gene expression of single mitochondria in live neurons using nanotweezers
Sahota, A., Nadappuram, B., Allerton, S. C., Lesept, F., Howden, J., Claxton, S., Liu, Y., Aprile, F. A., Kittler, J., Devine, M. J., Edel, J., Ivanov, A.
10.64898/2025.12.10.693488 — Posted: 2025-12-13
SPIN90 modulates the architecture of lamellipodial actin in an ARPC5L dependent fashion.
Cao, L., Basant, A., Mladenov, M., Kogata, N., Jegou, A., Romet-Lemonne, G., Brasselet, S., Mavrakis, M., Way, M.
10.64898/2025.12.01.691495 — Posted: 2025-12-02
The ERCC6L2-MRI-KU complex coordinates NHEJ at staggered DNA double-strand breaks.
Reichl, P. I., Sonmez, C., Sun, Y., King, A., Davies, B., Wilkinson, A. C., Lottersberger, F., Chapman, J. R.
10.1101/2025.11.28.691009 — Posted: 2025-11-28
Oncogenic RAS activity is linked to immune priming and adenosine-driven immune evasion in lung adenocarcinoma
de Carne Trecesson, S., East, P., Pillsbury, C., Silva dos Santos, M., Cha, H., Colliver, E., Gilmore, T., Rana, S., Moore, C., Lighterness, S., Caswell, D. R., Boumelha, J., Tomaschko, M., Baer, R., Eyles, J., Teixeira, B., Saeed, M., Litchfield, K., Molina-Arcas, M., Lee, S.-H., MacRae, J., Hobson, P., Swanton, C., Downward, J.
10.1101/2025.11.25.690426 — Posted: 2025-11-26
A divergent Plasmodium NEK4 acts as a key regulator driving the early events of meiosis
Yanase, R., Hair, M., Zeeshan, M., Ferguson, D. J. P., Brady, D., Pasquarello, C., Bottrill, A., Bhanvadia, S., Neal, A., Tromer, E. C., Le Roch, K. G., Hainard, A., Holder, A. A., Vaughan, S., Guttery, D. S., Tewari, R.
10.1101/2025.11.21.689802 — Posted: 2025-11-23

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