Channel: Francis Crick Institute

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

922 Articles

Blimp-1 and c-Maf regulate common and unique gene networks to protect against distinct pathways of pathobiont-induced colitis

Alvarez-Martinez, M., Cox, L. S., Pearson, C. F., Branchett, W. J., Chakravarty, P., Wu, X., Slawinski, H., Al Dibouni, A., Samelis, V., Gabrysova, L., Priestnall, S. L., Suarez-Bonnet, A., Mikolajczak, A., Briscoe, J., Powrie, F., O'Garra, A.

10.1101/2023.09.14.557705 — Posted: 2023-09-16

GOT1 primes the cellular response to hypoxia by supporting glycolysis and HIF1α stabilisation

Grimm, F., Asuaje, A., Jain, A., Silva dos Santos, M., Kleinjung, J., Nunes, P. M., Gehrig, S., Fets, L., MacRae, J., Anastasiou, D.

10.1101/2023.09.06.556522 — Posted: 2023-09-08

Molecular model of a bacterial flagellar motor in situ reveals a "parts-list" of protein adaptations to increase torque

Drobnic, T., Cohen, E. J., Alzheimer, M., Froschauer, K., Svensson, S., Singh, N., Garg, S. G., Henderson, L., Umrekar, T., Nans, A., Ribardo, D., Hochberg, G., Hendrixson, D. R., Sharma, C. M., Rosenthal, P., Beeby, M.

10.1101/2023.09.08.556779 — Posted: 2023-09-08

Raguseo, F., Huyghebaert, A., Li, J., Balendra, R., Petric Howe, m., Wang, Y., Vadukul, D. M., Tanase, D., Maher, T. E., Malouf, L., Rubio Sanchez, R., Aprile, F. A., Elani, Y., Patani, R., Di Michele, L., Di Antonio, M.

10.1101/2023.01.31.526399 — Posted: 2023-09-04

SCD inhibition eradicates AML displaying high de novo fatty acid desaturation and synergizes with chemotherapy

Dembitz, V., Lawson, H., Burt, R., Philippe, C., James, S. C., Atkinson, S., Durko, J., Wang, L. M., Campos, J., Magee, A. M., Woodley, K., Austin, M. J., Rio-Machin, A., Casado-Izquierdo, P., Bewicke-Copley, F., Rodriguez, G., Pereira, D., Oudejans, L., Boet, E., von Kriegsheim, A., Schwaller, J., Finch, A. J., Pate, B., Sarry, J.-E., Tamburini, J., Schuringa, J. J., Hazlehurst, L., Copland, J. A., Yuneva, M., Peck, B., Cutillas, P., Fitzgibbon, J., Rouault-Pierre, K., Kranc, K., Gallipoli, P.

10.1101/2023.08.02.551656 — Posted: 2023-09-04

Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring

Kuzmin, E., Baker, T. M., Lesluyes, T., Monlong, J., Abe, K. T., Coelho, P. P., Schwartz, M., Zou, D., Morin, G., Pacis, A., Yang, Y., Martinez, C., Barber, J., Kuasne, H., Li, R., Bourgey, M., Fortier, A.-M., Davison, P. G., Omeroglu, A., Guiot, M. C., Morris, Q., Kleinman, C. L., Huang, S., Gingras, A.-C., Ragoussis, I., Bourque, G., Van Loo, P., Park, M.

10.1101/2023.06.10.544434 — Posted: 2023-09-02

Unanticipated interacting features of human gut-associated lymphoid tissues link microbiota, intestinal immunity and autoimmunity

Montorsi, L., Pitcher, M. J., Zhao, Y., Demonti, A., Tull, T. J., Dionisi, C., Dhami, P., Ellis, R. J., Bishop, C., Sanderson, J., Jain, S., D'Cruz, D., Gibbons, D., Winkler, T. H., Bemark, M., Ciccarelli, F. D., Spencer, J.

10.1101/2023.08.29.555265 — Posted: 2023-08-31

Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma

Chan, A. W., Broncel, M., Yifrach, E., Haseley, N. R., Chakladar, S., Andree, E., Herneisen, A. L., Shortt, E., Treeck, M., Lourido, S.

10.1101/2023.01.11.523553 — Posted: 2023-08-29

Flow: a web platform and open database to analyse, store, curate and share bioinformatics data at scale

Capitanchik, C., Ireland, S., Harston, A., Cheshire, C., Jones, D. M., Lee, F. C. Y., Ruiz de los Mozos, I., Iosub, I. A., Kuret, K., Faraway, R., Wilkins, O. G., Arora, R., Hallegger, M., Modic, M., Chakrabarti, A. M., Luscombe, N. M., Ule, J.

10.1101/2023.08.22.544179 — Posted: 2023-08-29

Defective cytoskeletal dynamics underlies the essential role of MRTF-SRF in IL-2 delivery to CD8+ T cells during infectious challenge

Maurice, D., Costello, P., Gualdrini, F., Frederico, B., Treisman, R.

10.1101/2023.08.26.554941 — Posted: 2023-08-27

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