Channel:  Francis Crick Institute

1,183 Articles

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Mechanical fracturing of the extracellular matrix patterns the vertebrate heart
Jin Ji, C. C., Santos-Olivan, D., Ramel, M.-C., Sanchez-Posada, J., Paizakis, P., Andrews, T. G., Noel, E. S., Torres-Sanchez, A., Priya, R.
10.1101/2025.03.07.641942 — Posted: 2025-03-07
DEK::NUP214 acts as an XPO1-dependent transcriptional activator of essential leukemia genes
Kaya, F., Bewicke-Copley, F., Miettinen, J. J., Casado, P., Leddy, E., Deniz, O., Lavallee, V.-P., Philippe, C., Zheng, J., Grebien, F., Khan, N., Krizsan, S., Saad, J., Nolin-Lapalme, A., Lemieux, S., Audemard, E. O., Matthews, J., Grantham, M., Di Bella, D., Wennerberg, K., Parsons, A., Rio-Machin, A., Gribben, J., Cavenagh, J. D., Freeman, S. D., Bodor, C., Sauvageau, G., Wang, J., Llamas-Sillero, P., Cazier, J.-B., Taussig, D. C., Bonnet, D., Cutillas, P. R., Heckman, C., Fitzgibbon, J., Rouault-Pierre, K.
10.1101/2025.03.05.641116 — Posted: 2025-03-07
CAR-SPLASH identifies nascent pre-mRNA structures implicated in kinetic coupling and alternative splicing
Shenasa, H., Fong, N., Erickson, B., Iosub, I., Ule, J., Bentley, D.
10.1101/2025.03.02.641068 — Posted: 2025-03-06
Mechanism of DNA-protein crosslink bypass by CMG helicase
Kyaw, M. T., Xie, S., de Lamo Peitz, E., Yardimci, H.
10.1101/2025.03.06.641852 — Posted: 2025-03-06
A human induced pluripotent stem cell toolbox for studying sex chromosome effects
Meleckyte, R., Varsally, W., Zohren, J., Eriksson, J., Incitti, T., Starnes, L., Pointon, A., Hicks, R., Powell, B. E., Turner, J.
10.1101/2025.02.28.640277 — Posted: 2025-03-03
Astrocytic RNA editing regulates the host immune response to alpha-synuclein
D'Sa, K., Choi, M. L., Wagen, A. Z., Seto-Salvia, N., Kopach, O., Evans, J. R., Rodrigues, M., Lopez-Garcia, P., Lachica, J., Singh, J., Ghareeb, A., Bayne, J., Grant-Peters, M., Garcia-Ruiz, S., Chen, Z., Rodriques, S., Athauda, D., Gustavsson, E. K., Gagliano Taliun, S. A., Toomey, C., Reynolds, R. H., Young, G., Strohbuecker, S., Warner, T., Rusakov, D. A., Patani, R., Bryant, C., Klenerman, D. A., Gandhi, S., Ryten, M.
10.1101/2024.02.26.582055 — Posted: 2025-03-03
Salmonella effector kinase SteC is activated by host-mediated phosphorylation
Pillay, T. D., Lemetais, B., Huber, J., Diaz Del Olmo, I., Li, Y., Masino, L., Maslen, S., Liu, M., Esposito, D., Hinton, J. C. D., Yu, X.-J., Thurston, T. L. M., Rittinger, K.
10.1101/2025.03.01.640964 — Posted: 2025-03-02
Charting the liver and lung metastatic niche in breast cancer
Sznurkowska, M. K., Castro-Giner, F., Krol, I., Zhang, Y., Ozimski, L. L., D'Anna, I., Ring, A., Schwab, F. D., Zhang, Y. W., Zhou, J., Saini, M., Strittmatter, K., Budinjas, S., Vujanovic, M., Kontarakis, Z., Pontecorvi, G., Albrecht, F., Mertz, K. D., Auray, G., Giachino, C., Taylor, V., Gvozdenovic, A., Kovacs, W., Malanchi, I., Frauchiger-Heuer, H., Wicki, A., Vetter, M., Ligorio, M., Aceto, N.
10.1101/2024.10.04.616491 — Posted: 2025-02-28
Biochemical reconstitution of sister chromatid cohesion establishment during DNA replication
Minamino, M., Diffley, J., Uhlmann, F.
10.1101/2025.02.25.640040 — Posted: 2025-02-28
RAS-PI3K Pathway in CAFs Shapes Physicochemical Properties of Tumor ECM to Impact Tumor progression
Cuesta, C., Alcon-Perez, M., Zheng, J., Procel, N., Cota, R. R., Fennema, D., Rosell, A., Meson, D. L., Martinez-Castedo, B., Arafat, Y., Sanz-Fraile, H., Rajeeve, V., Alonso, D., Hynds, R. E., Swanton, C., Alcaraz, J., Cutillas, P., Reyes-Aldasoro, C. C., Wang, H., Castellano, E.
10.1101/2025.01.20.633776 — Posted: 2025-02-28

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