Channel:  Francis Crick Institute

1,252 Articles

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Multiscale mechanics drive functional maturation of the vertebrate heart
Andrews, T. G., Cornwall Scoones, J., Ramel, M.-C., Gupta, K., Briscoe, J., Priya, R.
10.1101/2024.07.24.604962 — Posted: 2024-07-30
2'-O-Methyl-guanosine 3-base RNA fragments mediate essential natural TLR7/8 antagonism
Alharbi, A., Sapkota, S., Zhang, Z., Jin, R., Jayasekara, W. S., Rupasinghe, E., Speir, M., Wilkinson-White, L., Gamsjaeger, R., Cubeddu, L., Ellyard, J. I., Wenholz, D., McAllan, A., Rezwan, R., Ying, L., Hosseini Far, H., Bones, J., He, S., Yu, D., Lennox, K., Hertzog, P. J., Vinuesa, C., Behlke, M. A., Ohto, U., Laczka, O., Corry, B., Shimizu, T., Gantier, M. P.
10.1101/2024.07.25.605091 — Posted: 2024-07-25
Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics
Biggs, G. S., Cawood, E. E., Vuorinen, A., McCarthy, W. J., Wilders, H., Riziotis, I. G., van der Zouwen, A. J., Pettinger, J., Nightingale, L., Chen, P., Powell, A. J., House, D., Boulton, S. J., Skehel, J. M., Rittinger, K., Bush, J. T.
10.1101/2024.07.25.605137 — Posted: 2024-07-25
ETV4 and ETV5 Orchestrate FGF-Mediated Lineage Specification and Epiblast Maturation during Early Mouse Development
Simon, C. S., Garg, V., Kuo, Y.-Y., Niakan, K. K., Hadjantonakis, A.-K.
10.1101/2024.07.24.604964 — Posted: 2024-07-24
ATG9A and ARFIP2 cooperate to regulate PI4P levels for lysosomal repair
De Tito, S., Almacellas, E., Yu, D. D., Zhang, W., Millard, E., Hervas, J. H., Pellegrino, E., Panagi, I., Fodge, D., Thurston, T. L. M., Gutierrez, M., Tooze, S.
10.1101/2024.07.23.604321 — Posted: 2024-07-24
Super-resolution imaging of proteins inside live mammalian cells with mLIVE-PAINT
Bhaskar, H., Gidden, Z., Virdi, G., Kleinjan, D.-J., Rosser, S. J., Gandhi, S., Regan, L., Horrocks, M. H.
10.1101/2024.07.22.604574 — Posted: 2024-07-22
Multi-Omic Analysis Reveals Lipid Dysregulation Associated with Mitochondrial Dysfunction in Parkinson's Disease Brain
Hallqvist, J., Toomey, C. E., Pinto, R., Wernick, A., Shahrani, M., Heales, S., Eaton, S., Mills, K., Gandhi, S., Heywood, W. E.
10.1101/2024.07.18.604051 — Posted: 2024-07-22
STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair
van den Heuvel, D., Rodriguez-Martinez, M., van der Meer, P. J., Nieto Moreno, N., Park, J., Kim, H.-S., van Schie, J. J., Wondergem, A. P., D'Souza, A., Yakoub, G., Herlihy, A., Kashyap, K., Boissiere, T., Walker, J., Mitter, R., Apelt, K., de Lint, K., Kirdok, I., Ljungman, M., Wolthuis, R. M., Cramer, P., Scharer, O. D., Kokic, G., Svejstrup, J. Q., Luijsterburg, M. S.
10.1101/2024.07.22.604575 — Posted: 2024-07-22
Structures of TGF-beta with betaglycan and the signaling receptors reveal the mechanism whereby betaglycan potentiates receptor complex assembly and signaling
Wieteska, L., Taylor, A. B., Punch, E., Coleman, J. A., Conway, I. O., Lin, Y.-F., Byeon, C.-H., Hinck, C. S., Krzysiak, T., Ishima, R., Lopez-Casillas, F., Cherepanov, P., Bernard, D. J., Hill, C. S., Hinck, A. P.
10.1101/2024.07.19.604101 — Posted: 2024-07-22
Systematic identification of Y-chromosome gene functions in mouse spermatogenesis
Subrini, J., Varsally, W., Balaguer Balsells, I., Bensberg, M., Sioutas, G., Ojarikre, O., Maciulyte, V., Gylemo, B., Crawley, K., Courtis, K., de Rooij, D. G., Turner, J. M.
10.1101/2024.07.18.604063 — Posted: 2024-07-19

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