Channel:  Francis Crick Institute

1,177 Articles

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Nonlinear readout of spatial cues underlies robustness of asymmetric cell division
Rodrigues, N. T. L., Bland, T., Ng, K., Hirani, N., Goehring, N.
10.1101/2023.11.21.568006 — Posted: 2023-11-21
Creation of de novo cryptic splicing for ALS/FTD precision medicine
Wilkins, O. G., Chien, M. Z. Y. J., Wlaschin, J. J., Pisliakova, M., Thompson, D., Digby, H., Simkin, R. L., Diaz, J. A., Mehta, P. R., Keuss, M. J., Zanovello, M., Brown, A.-L., Harley, P., Darbey, A., Karda, R., Fisher, E. M. C., Cunningham, T. J., Le Pichon, C. E., Ule, J., Fratta, P.
10.1101/2023.11.15.565967 — Posted: 2023-11-15
Epi-microRNA mediated metabolic reprogramming ensures affinity maturation
Nakagawa, R., Llorian, M., Varsani-brown, S., Chakravarty, P., Camarillo, J. M., Barry, D., George, R., Blackledge, N. P., Duddy, G., Kelleher, N. L., Klose, R. J., Turner, M., Calado, D. P.
10.1101/2023.07.31.551250 — Posted: 2023-10-31
Telomere protein arrays stall DNA loop extrusion by condensin
Analikwu, B. T., Deshayes, A., van der Torre, J., Guerin, T., Katan, A. J., Beneut, C., Barth, R., Phipps, J., Scolari, V., Veaute, X., Barrington, C., Busso, D., Uhlmann, F., Dubrana, K., Mattarocci, S., Dekker, C., Marcand, S.
10.1101/2023.10.29.564563 — Posted: 2023-10-29
The history of chromosomal instability in genome doubled tumors
Baker, T. M., Lai, S., Lesluyes, T., Yan, H., Verfaillie, A., Dentro, S., Lynch, A. R., Bowes, A. L., Pillay, N., Flanagan, A. M., Swanton, C., Tarabichi, M., Van Loo, P.
10.1101/2023.10.22.563273 — Posted: 2023-10-25
Genome-wide CRISPR/Cas9 screen identifies MAT2A as a critical host factor for BK Polyomavirus
Caller, L., Ho, S., Brown, K., Dupont, L., Zaletel, T., Beale, R., Lehner, P. J., Crump, C. M.
10.1101/2023.10.20.563362 — Posted: 2023-10-21
Aminoglycoside heteroresistance in Enterobacter cloacae is driven by the cell envelope stress response.
Choi, A. J., Bennison, D. J., Kulkarni, E., Sun, H., Li, H., Bradshaw, J., Yeap, H. W., Lim, N., Mishra, V., Crespo-Puig, A., Davies, F., Sriskandan, S., Shenoy, A. R.
10.1101/2023.10.11.561937 — Posted: 2023-10-17
Pan-cancer evolution signatures link clonal expansion to dynamic changes in the tumour immune microenvironment
Yang, X., Liu, W., Mackintyre, G., Loo, P. V., Markowetz, F., Bailey, P., Yuan, K.
10.1101/2023.10.12.560630 — Posted: 2023-10-13
WNK1-dependent water influx is required for CD4+ T cell activation and T cell-dependent antibody responses
Biggs O'May, J., Vanes, L., de Boer, L., Hartweger, H., Kunzelmann, S., Hayward, D., Llorian, M., Lewis, D. A., Koechl, R., Tybulewicz, V.
10.1101/2022.03.16.484637 — Posted: 2023-09-30
T cell migration requires ion and water influx to regulate actin polymerization
de Boer, L., Vanes, L., Melgrati, S., Biggs O'May, J., Hayward, D., Driscoll, P., Day, J., Griffiths, A., Magueta, R., Morrell, A., MacRae, J. I., Koechl, R., Tybulewicz, V.
10.1101/2022.03.16.484584 — Posted: 2023-09-30

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