Channel:  The Howard Hughes Medical Institute (HHMI)

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Structural remodeling of target-SNARE protein complexes by NSF enables synaptic transmission
White, K. I., Khan, Y. A., Qiu, K., Balaji, A., Couoh-Cardel, S., Esquivies, L., Pfuetzner, R. A., Diao, J., Brunger, A. T.
10.1101/2024.10.11.617886 — Posted: 2025-07-10
Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2
Chen, S., Basiashvili, T., Hutchings, J., Murillo, M. S., Suarez, A. V., Xiong, E., Louro, J. A., Leschziner, A. E., Villa, E.
10.1101/2024.06.18.599606 — Posted: 2025-07-10
A Congenic C57BL/6 rd1 Mouse Model for Retinal Degeneration Research
Chandler, L. C., Gardner, A., Cepko, C. L.
10.1101/2025.07.09.663548 — Posted: 2025-07-09
Glycogen phase separation drives macromolecular rearrangement and asymmetric division in Escherichia coli
Thappeta, Y., Canas-Duarte, S. J., Wang, H., Kallem, T., Fragasso, A., Xiang, Y., Gray, W., Lee, C., Hardo, G., Cegelski, L., Jacobs-Wagner, C.
10.1101/2024.04.19.590186 — Posted: 2025-07-08
Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer
Koochaki, P., Qiu, B., Coker, J. A., Earsley, A., Wang, N. S., Romigh, T., Goins, C. M., Stauffer, S. R., Boudker, O., Chakraborty, A. A.
10.1101/2025.07.03.663021 — Posted: 2025-07-07
Ultrasound imaging of in situ transcriptional activity in opaque tissue
Shivaei, S., Cheung, K. Y. M., Yadav, A., Hurvitz, I. U., Lee, S., Revilla, J., Rabut, C., Criado-Hidalgo, E., Zhang, R. J., Shapiro, M. G.
10.1101/2025.07.06.663365 — Posted: 2025-07-07
Population differences of chromosome 22q11.2 duplication structure predispose differentially to microdeletion and inversion.
Porubsky, D., Yoo, D., Dishuck, P. C., Koundinya, N., Souche, E., Harvey, W. T., Munson, K. M., Hoekzema, K., Chan, D. D., Leung, T. Y., Santos, M. S., Meynants, S., Swillen, A., Breckpot, J., Tsapalou, V., Hasenfeld, P., Korbel, J. O., Lansdorp, P. M., Vermeesch, J. R., Eichler, E. E.
10.1101/2025.07.04.662981 — Posted: 2025-07-07
Discovery of oxyacanthine dihydrochloride monohydrate polymorphs from obfuscated samples by MicroED
Lin, J., Paz, O., Unge, J., Gonen, T.
10.1101/2025.07.03.663078 — Posted: 2025-07-05
Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex
Salazar, M. P. R., Kolanukuduru, S., Ramirez, V., Lyu, B., Manigault, G., Sejourne, G., Sesaki, H., Yu, G., Eroglu, C.
10.1101/2024.10.22.619706 — Posted: 2025-07-03
Multimodal profiling of proinflammatory protease activity identifies caspase-1 as a target for lung cancer interception
Wang, C. S., Zhong, Q., Wang, S.-T., Alonso, M. C. M., Neaher, S., Patel, S., Parisi, T., Kirkpatrick, J. D., Sequist, L. V., Jacks, T. E., Bhatia, S.
10.1101/2025.07.01.662195 — Posted: 2025-07-02

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