Channel:  The Howard Hughes Medical Institute (HHMI)

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Aminoacyl-tRNA specificity of a ligase catalyzing non-ribosomal peptide extension
Nguyen, D. T., Ramos-Figueroa, J. S., Vinogradov, A. A., Goto, Y., Gadgil, M. G., Splain, R. A., Suga, H., van der Donk, W. A., Mitchell, D. A.
10.1101/2025.09.13.676032 — Posted: 2025-09-14
Safety and immunogenicity of PanChol, a single-dose live-attenuated oral cholera vaccine: results from a phase 1a, double-blind, randomized, placebo-controlled trial
Leitner, D. R., Walsh, S. R., Suzuki, M., Desjardins, M., Hannaford, A., Sherman, A. C., Levine, H., Carr, L., Hammerness, E., Osaki, A., Sullivan, E., Wang, B., Balazs, G. I., Chang, J. B. P., Slater, D. M., Puri, N., Kuehl, C. J., Chen, W. H., Harris, J. B., Piantadosi, S., Baden, L. R., Waldor, M. K., PanChol study group
10.1101/2025.09.12.25335655 — Posted: 2025-09-14
marApp: An R package and web portal to calculate mutations- and genetic diversity-area relationship for conservation
Lin, M., Mualim, K., Selmoni, O., Exposito-Alonso, M.
10.1101/2025.09.09.675155 — Posted: 2025-09-14
ACAD10 encodes two orphan enzymes in the ether lipid biosynthetic and salvage pathways
Ye, J., Purlyte, E., Lopez, V. A., Kizzar, T., Tatge, L., Mill, J., Baldwin, D., Rashan, E., Kim, J., Pagliarini, D. A., Tomchick, D. R., Pawlowski, K., Douglas, P., Simcox, J., Tagliabracci, V. S.
10.1101/2025.09.10.675409 — Posted: 2025-09-13
Neutral lipid processing in glia is sexually dimorphic and promotes sleep through diacylglycerol catabolism
Pyfrom, E. S., Beveridge, C., Haynes, P. R., Kanigicherla, V. A., Randolph, C. E., Carvalho Costa, P., Negatu, S. G., Iyer, S., Killiany, S. L., Yue, Z., Astacio, E. N., Walker, K. A., Luu, K. N., Pivarshev, P. A., Jurado, K. A., Chopra, G., Sehgal, A.
10.1101/2025.09.10.674993 — Posted: 2025-09-12
Atlas of innate immune responses to experimental cholera and IL22 treatment demonstrates protection by mucus-secreting cells
Suzuki, M., Hasegawa, Y., Zhang, H., Waldor, M. K.
10.1101/2025.09.12.675873 — Posted: 2025-09-12
HIF2-driven PTHrP Causes Cachexia and Hypercalcemia in Kidney Cancer: Treatment with HIF2 Inhibitors
Abu-Remaileh, M., Stransky, L. A., Bhalerao, N., Shirole, N. H., Jiang, Q., Saad, E., Machaalani, M., Vigeant, S. H., Woldemichael, H., Xu, C., Lu, J., Wei, H., Liu, Z., Sun, W., Enomoto, K., Choueiri, T. K., Pitarresi, J. R., Carr, S. A., Udeshi, N. D., Kaelin, W. G.
10.1101/2025.09.09.675147 — Posted: 2025-09-11
The gut microbiota directs vitamin A flux to regulate intestinal T cell development
Srinivasan, T., Dende, C., Ruhn, K. A., Moye, S. L., Johnson, A., Behrendt, C. L., Hassell, B., Vale, G., Kim, J., Lichterman, J. N., Liang, C., Arana, C., Raj, P., Zhan, X., McDonald, J. G., Koh, A. Y., Hooper, L. V.
10.1101/2025.09.08.674524 — Posted: 2025-09-10
Mammalian ZAP and KHNYN can independently restrict CpG-enriched avian viruses
Becker, J. T., Mickelson, C. K., Pross, L. M., Sanders, A. E., Vogt, E. R., Shepherd, F. K., Wick, C., Barkhymer, A. J., Aron, S. L., Fay, E. J., Harris, R. S., Langlois, R. A.
10.1101/2024.12.23.629495 — Posted: 2025-09-10
A green lifetime biosensor for calcium that remains bright over its full dynamic range
van der Linden, F. H., Thornquist, S. C., ter Beek, R. M., Huijts, J. Y., Hink, M. A., Gadella, T. W. J., Maimon, G., Goedhart, J.
10.1101/2024.11.05.622032 — Posted: 2025-09-10

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