Channel:  The Howard Hughes Medical Institute (HHMI)

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The Drosophila ovary produces three follicle waves similar to those in mice
Fu, W. Y., Spradling, A. C.
10.1101/2025.11.11.687893 — Posted: 2025-11-18
Imp1 acts as a dosage- and stage-dependent temporal rheostat orchestrating radial glial fate transitions and cortical morphogenesis
Azur, R. A. G., Feliciano, D., Espinosa-Medina, I., Adhikari, R., Lilao-Garzon, J., Jansen, E., Yang, C.-P., Lee, T.
10.1101/2025.11.18.688993 — Posted: 2025-11-18
Structure and mechanism of microtubule stabilization and motor regulation by MAP9
Cetin, B., Taheri, A., Golcuk, M., Monroy, B. Y., Fernandes, J., Ori-McKenney, K. M., Gur, M., Nogales, E., Yildiz, A.
10.1101/2025.11.17.688911 — Posted: 2025-11-17
Structural Basis for Iterative Methylation by a Cobalamin-dependent Radical S-Adenosylmethionine Enzyme in Cystobactamids Biosynthesis
Cui, J., Wang, B., Maurya, R., Booker, S. J.
10.1101/2025.11.17.688841 — Posted: 2025-11-17
Near-atomistic simulations reveal the molecular principles that control chromatin structure and phase separation
Russell, K., Chen, Y., Espinosa, J. R., Gil, D. F., Zhou, H., Maristany, M. J., Lopez, J. I. P., Huertas, J., Orozco, M., Rosen, M. K., Collepardo-Guevara, R.
10.1101/2025.11.17.688899 — Posted: 2025-11-17
ecDNA-driven oncogene super-expressors shape immunoevasive tumor microenvironment
Qiao, K., Yang, Q.-L., Li, T., Chen, X., Yazgan, Z., Kim, Y. J., Gilbreath, C., Lim, J. Y. S., Xie, Y., Sun, X., Liu, Y., Jia, Y., Chen, Z. J., Huang, H., Wu, S.
10.1101/2025.11.15.688565 — Posted: 2025-11-16
Predicting Future Development of Stress-Induced Anhedonia From Cortical Dynamics and Facial Expression
Coley, A., Batra, K., Delahanty, J., Keyes, L., Pamintuan, R., Ramot, A., Hagemann, J., Lee, C., Liu, V., Adivikolanu, H., Cressy, J., Jia, C., Massa, F., LeDuke, D., Gabir, M., Durubeh, B., linderhof, L., Patel, R., Wichmann, R., Li, H., Fischer, K., Pereira, T., Tye, K.
10.1101/2024.12.18.629202 — Posted: 2025-11-15
FOXA1 mutations co-opt nascent transcription factor networks in partnership with androgen receptor to enhance prostate tumorigenicity
Ladewig, E., Nazir, A., Park, T., Fan, V. B., Cao, Z., Hawk, J., Kelly, L., Tjian, R., Leslie, C. S., Sawyers, C.
10.1101/2025.11.13.688263 — Posted: 2025-11-14
Modulating MyoD1 dosage activates alternate cell fate beyond myogenic differentiation
Whitney, O. N., Dailey, G. M., McKenna, J. K., Darzacq, X., Tjian, R.
10.1101/2025.11.13.688391 — Posted: 2025-11-14
Massively parallel reporter assay for mapping gene-specific regulatory regions at single nucleotide resolution
Tulloch, A. J., Delgado, R. N., Catta-Preta, R., Cepko, C. L.
10.1101/2025.05.13.653746 — Posted: 2025-11-14

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