Channel:  The Howard Hughes Medical Institute (HHMI)

2,582 Articles

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Deconvolving SARS-CoV-2 mRNA vaccine impact on immunotherapy-related survival in a pandemic
Jee, J., Zhang, J., Lavery, J., Waters, M., Fong, C., Minn, A., Glickman, M., Panageas, K., Sawyers, C., Schultz, N.
10.1101/2025.11.21.25340753 — Posted: 2025-11-23
Nucleotide context models outperform protein language models for predicting antibody affinity maturation
Johnson, M. M., Sung, K., Haddox, H. K., Vora, A. A., Araki, T., Victora, G. D., Song, Y. S., Fukuyama, J., Matsen, F. A.
10.1101/2025.06.16.659977 — Posted: 2025-11-20
RNA switch model for localization and translation of the myelin basic protein mRNA
Topkar, V. V., Wu, V., Ho, L. T., Ambiel, N., Valenzuela, A., Yoshimura, K., Zuchero, J. B., Fu, M.-m., Das, R.
10.1101/2025.11.19.689361 — Posted: 2025-11-20
Targeting peptide-MHC complexes with designed T cell receptors and antibodies
Motmaen, A., Jude, K. M., Wang, N., Minervina, A., Feldman, D., Lichtenstein, M. A., Ebenezer, A., Correnti, C., Thomas, P. G., Garcia, K. C., Baker, D., Bradley, P.
10.1101/2025.11.19.689381 — Posted: 2025-11-20
Unconventional linkers facilitate potent stabilized coronavirus stem antibody responses following nanoparticle vaccination
Dzuvor, C. K. O., Moak, S. P., McManus, L. R., Dzordzorme, A. E., Evanson, L. R., Kim, T., Thomas, A., Adeyemi, O., Foley, V., Limaye, A., McNamara, R. P., Corbett-Helaire, K. S.
10.1101/2025.11.19.689216 — Posted: 2025-11-19
Rapid neocortical network modifications via dendritic plateau potential induced plasticity
Xiao, K., Li, Y., Sullivan, B. J., Li, G., Magee, J. C.
10.1101/2025.11.19.689338 — Posted: 2025-11-19
De novo Design of All-atom Biomolecular Interactions with RFdiffusion3
Butcher, J., Krishna, R., Mitra, R., Brent, R. I., Li, Y., Corley, N., Kim, P. T., Funk, J., Mathis, S. V., Salike, S., Muraishi, A., Eisenach, H., Thompson, T. R., Chen, J., Politanska, Y., Sehgal, E., Coventry, B., Zhang, O., Qiang, B., Didi, K., Kazman, M., DiMaio, F., Baker, D.
10.1101/2025.09.18.676967 — Posted: 2025-11-19
Imp1 acts as a dosage- and stage-dependent temporal rheostat orchestrating radial glial fate transitions and cortical morphogenesis
Azur, R. A. G., Feliciano, D., Espinosa-Medina, I., Adhikari, R., Lilao-Garzon, J., Jansen, E., Yang, C.-P., Lee, T.
10.1101/2025.11.18.688993 — Posted: 2025-11-18
Structural Basis for Iterative Methylation by a Cobalamin-dependent Radical S-Adenosylmethionine Enzyme in Cystobactamids Biosynthesis
Cui, J., Wang, B., Maurya, R., Booker, S. J.
10.1101/2025.11.17.688841 — Posted: 2025-11-17
ecDNA-driven oncogene super-expressors shape immunoevasive tumor microenvironment
Qiao, K., Yang, Q.-L., Li, T., Chen, X., Yazgan, Z., Kim, Y. J., Gilbreath, C., Lim, J. Y. S., Xie, Y., Sun, X., Liu, Y., Jia, Y., Chen, Z. J., Huang, H., Wu, S.
10.1101/2025.11.15.688565 — Posted: 2025-11-16

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