Channel:  The Howard Hughes Medical Institute (HHMI)

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Influence of phosphate activation chemistry on the selection of the primordial genetic alphabet
Boskovic, F., Zhang, J., Swatiputra, A. A., Szostak, J. W.
10.64898/2025.12.23.696203 — Posted: 2025-12-25
Rapid fluorescence lifetime sensor development of LifeCamp enables transient and baseline absolute calcium measurements
Lodder, B., Raghubardayal, M., Ganesh, S., Cai, X., Stern, J., Sherman, M., Rosen, P., Kamath, T., Hartman, I., Siegel, M., Timmins, J., Adan, R., Andermann, M. L., Sabatini, B. L.
10.64898/2025.12.23.696288 — Posted: 2025-12-25
Genetically engineered ESC-derived embryos reveal Vinculin-dependent force responses required for mammalian neural tube closure
Prudhomme, I. S., Brooks, E. R., Taneja, N., Bhattacharya, B., LaFleche, B. J., Furuta, Y., Zallen, J. A.
10.64898/2025.12.22.696028 — Posted: 2025-12-25
Oxidative Peptide Backbone Cleavage by a HEXXH Enzyme During RiPP Biosynthesis
Ouyang, Y., Yu, Y., Zhu, L., Nguyen, D., van der Donk, W.
10.1101/2025.10.30.685615 — Posted: 2025-12-25
Mechanisms of HSV-1 helicase-primase inhibition and replication fork complex assembly
Yu, Z., Sathyanarayana, P., Lui, C., Yang, P., Weller, S. K., Shekhar, M., Coen, D. M., Loparo, J., Abraham, J.
10.64898/2025.12.23.696259 — Posted: 2025-12-24
Vibrio cholerae serotype impacts pathogenicity
Zingl, F. G., Leitner, D. R., Fakoya, B., Morano, A. A., Waldor, M. K.
10.64898/2025.12.23.696279 — Posted: 2025-12-24
A SNP panel for co-analysis of capture and shotgun ancient DNA data
Fournier, R., Pearson Fulton, A., Reich, D. E.
10.1101/2025.07.30.667733 — Posted: 2025-12-23
Gut microbiota gate host exposure to cholinesterase inhibitors from dietary Solanums
Liou, C. S., Louwies, T., Iakiviak, M., Rajniak, J., Murugkar, P. P., Higginbottom, S. K., Weakley, A., Meng, X., Htet, P., Cabrera, A. V., Jasper, M., Dimas, A., Schulman, E. A., Fischbach, M. A., Kashyap, P., Sattely, E. S.
10.1101/2024.03.20.584512 — Posted: 2025-12-23
A silent Kv channel subunit shapes PV neuron action potential waveform and short-term synaptic plasticity during high-frequency firing
Ganesh, S., Canty, T. M., Sabatini, B. L.
10.1101/2025.11.06.686832 — Posted: 2025-12-22
Mitochondrial control of fuel switching via carnitine biosynthesis
Auger, C., Nishida, H., Yuan, B., Silva, G. M., Fujimoto, M., Li, M., Katoh, D., Wang, D., Granath-Panelo, M., Shin, J., Verkerke, A., Banks, A., Hui, S. T., Sun, L., Yook, J.-S., Witte, R., Kajimura, S.
10.64898/2025.12.16.694762 — Posted: 2025-12-20

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