Channel:  The Howard Hughes Medical Institute (HHMI)

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Contrasting patterns of somatic mutations in neurons and glia reveal differential predisposition to disease in the aging human brain
Ganz, J., Luquette, L. J., Bizzotto, S., Bohrson, C., Jin, H., Miller, M. B., Zhou, Z., Galor, A., Park, P. J., Walsh, C. A.
10.1101/2023.01.14.523958 — Posted: 2023-01-14
A nanoparticle priming agent reduces cellular uptake of cell-free DNA and enhances the sensitivity of liquid biopsies
Martin Alonso, C., Tabrizi, S., Xiong, K., Blewett, T., Patel, S., An, Z., Sridhar, S., Bekdemir, A., Shea, D., Amini, A. P., Wang, S.-T., Kirkpatrick, J., Rhoades, J., Golub, T., Love, J. C., Adalsteinsson, V., Bhatia, S.
10.1101/2023.01.13.524003 — Posted: 2023-01-14
Transplantation-based screen uncovers inducers of muscle progenitor cell engraftment across vertebrate species
Tavakoli, S., Garcia, V., Gahwiler, E., Adatto, I., Rangan, A., Messemer, K., Ashrafi Kakhki, S., Yang, S., Chan, V., Manning, M., Fotowat, H., Wagers, A., Zon, L.
10.1101/2023.01.13.523942 — Posted: 2023-01-14
An intravenous DNA-binding priming agent protects cell-free DNA and improves the sensitivity of liquid biopsies
Tabrizi, S., Martin-Alonso, C., Xiong, K., Blewett, T., Sridhar, S., An, Z., Patel, S., Rodriguez-Aponte, S. A., Naranjo, C. A., Wang, S.-T., Shea, D., Golub, T., Bhatia, S., Adalsteinsson, V., Love, J. C.
10.1101/2023.01.13.523947 — Posted: 2023-01-14
Design of amyloidogenic peptide traps
Sahtoe, D. D., Andrzejewska, E. A., Han, H. L., Rennella, E., Schneider, M. M., Meisl, G., Ahlrichs, M., Decarreau, J., Nguyen, H., Kang, A., Levine, P. M., Lamb, M., Li, X., Bera, A. K., Kay, L. E., Knowles, T., Baker, D.
10.1101/2023.01.13.523785 — Posted: 2023-01-13
Bacterial meningitis in the early postnatal mouse studied at single-cell resolution
Wang, J., Rattner, A., Nathans, J.
10.1101/2023.01.11.523597 — Posted: 2023-01-11
Aclarubicin stimulates RNA polymerase II elongation at closely spaced divergent promoters
Wooten, M., Takushi, B., Ahmad, K., Henikoff, S.
10.1101/2023.01.09.523323 — Posted: 2023-01-10
Arabidopsis TRB proteins function in H3K4me3 demethylation by recruiting JMJ14
Wang, M., Zhong, Z., Gallego-Bartolome, J., Feng, S., Shih, Y.-H., Liu, M., Zhou, J., Richey, J. C., Ng, C., Jami-Alahmadi, Y., Wohlschlegel, J., Wu, K., Jacobsen, S. E.
10.1101/2023.01.10.523456 — Posted: 2023-01-10
Spatial transcriptomics reveals a conserved segment polarity program that governs muscle patterning in Nematostella vectensis
He, S., Shao, W., Chen, S., Wang, T., Gibson, M.
10.1101/2023.01.09.523347 — Posted: 2023-01-10
The MOM1 complex recruits the RdDM machinery via MORC6 to establish de novo DNA methylation.
Li, Z., Wang, M., Zhong, Z., Gallego-Bartolome, J., Feng, S., Jami-Alahmadi, Y., Wang, X., Wohlschlegel, J., Bischof, S., Long, J. A., Jacobsen, S. E.
10.1101/2023.01.10.523455 — Posted: 2023-01-10

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