Channel:  The Howard Hughes Medical Institute (HHMI)

1,923 Articles

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Designed Endocytosis-Triggering Proteins mediate Targeted Degradation and amplify signaling
Huang, B., Abedi, M., Ahn, G., Coventry, B., Sappington, I., Wang, R., Schlichthaerle, T., Zhang, J. Z., Wang, Y., Goreshnik, I., Chiu, C. W., Chazin-Gray, A., Chan, S., Gerben, S., Murray, A., Wang, S., O'Neill, J., Yeh, R., Misquith, A., Wolf, A., Tomasovic, L. M., Piraner, D. I., Gonzalez, M. J. D., Bennett, N. R., Venkatesh, P., Satoe, D., Ahlrichs, M., Dobbins, C., Yang, W., Wang, X., Vafeados, D., Mout, R., Shivaei, S., Cao, L., Carter, L., Stewart, L., Spangler, J. B., Bernardes, G. J. L., Roybal, K. T., Greisen, P., Li, X., Bertozzi, C., Baker, D.
10.1101/2023.08.19.553321 — Posted: 2023-09-20
Model-directed generation of CRISPR-Cas13a guide RNAs designs artificial sequences that improve nucleic acid detection
Mantena, S., Pillai, P. P., Petros, B. A., Welch, N. L., Myhrvold, C., Sabeti, P. C., Metsky, H. C.
10.1101/2023.09.20.557569 — Posted: 2023-09-20
De novo designed Hsp70 activator dissolves intracellular condensates
Zhang, J. Z., Greenwood, N., Hernandez, J., Cuperus, J. T., Huang, B., Ryder, B. D., Queitsch, C., Gestwicki, J. E., Baker, D.
10.1101/2023.09.18.558356 — Posted: 2023-09-19
Double-Strand Break Repair Pathways Differentially Affect Processing and Transduction by Dual AAV Vectors
Maurer, A. C., Benyamini, B., Fan, V. B., Whitney, O. N., Dailey, G. M., Darzacq, X., Weitzman, M. D., Tjian, R.
10.1101/2023.09.19.558438 — Posted: 2023-09-19
Structural basis of TRPV1 modulation by endogenous bioactive lipids
Arnold, W. R., Mancino, A. S., Moss, F. R., Frost, A., Julius, D., Cheng, Y.
10.1101/2023.05.11.540281 — Posted: 2023-09-19
Genome-wide Characterization of Diverse Bacteriophages Enabled by RNA-Binding CRISPRi
Adler, B. A., Al-Shimary, M. J., Patel, J. R., Ambruster, E., Colognori, D., Charles, E. J., Miller, K. V., Lahiri, A., Trinidad, M., Boger, R., Nomburg, J., Beurnier, S., Cui, M. L., Barrangou, R., Mutalik, V. K., Schoeniger, J. S., Pogliano, J. A., Savage, D. F., Doudna, J. A., Cress, B. F.
10.1101/2023.09.18.558157 — Posted: 2023-09-18
A proposed function for the red body of Nannochloropsis in the formation of the recalcitrant cell wall polymer, algaenan
Gee, C. W., Andersen-Ranberg, J., Rosen, R. Z., Jorgens, D., Grob, P., Holman, H.-Y., Niyogi, K. K.
10.1101/2023.09.17.558137 — Posted: 2023-09-17
Structure-Activity Relationship Studies of Novel Gut-derived Lantibiotics Against Human Gut Commensals
Zhang, Z. J., Wu, C., Dorantes, D., Pappas, T., Sundararajan, A., Lin, H., Pamer, E. G., van der Donk, W. A.
10.1101/2023.09.15.557961 — Posted: 2023-09-17
The diverse evolutionary histories of domesticated metaviral capsid genes in mammals
Henriques, W. S., Young, J. M., Nemudryi, A., Nemudraia, A., Wiedenheft, B., Malik, H. S.
10.1101/2023.09.17.558119 — Posted: 2023-09-17
General Transcription Factor from E. coli with a Distinct Mechanism of Action
Nudler, E., Vasilyev, N., Liu, M., Epshtein, V., Shamovsky, I.
10.1101/2023.09.17.558134 — Posted: 2023-09-17

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