Channel:  The Howard Hughes Medical Institute (HHMI)

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Geometric Tuning of Cytokine Receptor Association Modulates Synthetic Agonist Signaling
Exposit, M., Abedi, M., Krishnakumar, A., Jain, S., Yu, T.-Y., Hercus, T. R., Mathew, D., Gray-Gaillard, S., Chen, Z., Grubbe, W. S., Favor, A., Kan, W. L., Schlichthaerle, T., Chen, W., Parker, M. W., Mendoza, J. L., Lopez, A. F., Wherry, E. J., Baker, D.
10.1101/2025.10.12.681819 — Posted: 2025-10-13
Multiplex design and discovery of proximity handles for programmable proteome editing
Suiter, C. C., Ahn, G., Chiu, M., Fu, Y., Sadre, S., Simon, J. J., Lee, D. S., Fowler, D. M., Maly, D. J., Baker, D., Shendure, J.
10.1101/2025.10.13.681693 — Posted: 2025-10-13
Ultra-mild bisulfite outperforms existing methods for 5-methylcytosine detection with low input DNA
He, C., Dai, Q., Baldwin, T., Lyu, R., Daniels, B., Ye, C., Cao, C., Zhu, C., Fan, D., Lin, L., Liu, Y., Wang, Y.
10.1101/2025.10.09.681456 — Posted: 2025-10-11
A family of lethal exotoxins defined by cell entry via the Attractin receptor
Viswanatha, R., Lee, D., Robins, W. P., Mameli, E., Hu, Y., Kim, A.-R., Hashmi, Y., Nishida, H., Prakash, G., Butnaru, M., Churchman, L. S., Mohr, S., Mekalanos, J., Perrimon, N.
10.1101/2025.10.08.681221 — Posted: 2025-10-11
Kinase KEY1 controls pyrenoid condensate size throughout the cell cycle by disrupting phase separation interactions
He, S., Lemma, L. M., Martinez-Calvo, A., He, G., Hennacy, J. H., Wang, L., Ergun, S. L., Rai, A. K., Wang, C., Bunday, L., Kayser-Browne, A., Wang, Q., Brangwynne, C. P., Wingreen, N. S., Jonikas, M. C.
10.1101/2025.10.09.681382 — Posted: 2025-10-10
Cell type- and chromosome-specific chromatin landscapes and DNA replication programs of Drosophila testis tumor stem-cell like cells
Urban, J., Ringwalt, D., Urban, J., Xue, W., Gleason, R., Zhao, K., Chen, X.
10.1101/2025.04.19.649648 — Posted: 2025-10-10
Vascular endothelial-specific loss of TGF-beta signaling as a model for choroidal neovascularization and central nervous system vascular inflammation
Wang, Y., Rattner, A., Li, Z., Smallwood, P. M., Nathans, J.
10.1101/2025.04.11.648449 — Posted: 2025-10-09
Induction of menstruation in mice reveals the regulation of menstrual shedding
Cevrim, C., Hilgert, N. J., Kaage, A. M., Russell, A. J. C., Goldstein, A. E., Ang, C. J., Gable, J. L. R., Bagamery, L. E., Breznik, A., Di Bella, D. J., Talay, M., Peng, J., O'Neill, K. E., Chen, F., Eddy, S. R., McKinley, K. L.
10.1101/2025.10.08.681007 — Posted: 2025-10-09
GMCL1 Controls 53BP1 Stability and Modulates Taxane Sensitivity
Kito, Y., Gonzalez-Robles, T. J., Kaisari, S., Pae, J., Garcia, S. F., Ortiz-Pacheco, J., Ueberheide, B., Marzio, A., Rona, G., Pagano, M.
10.1101/2025.03.18.643855 — Posted: 2025-10-08
RNA sequence design and protein-DNA specificity prediction with NA-MPNN
Kubaney, A., Favor, A. H., McHugh, L., Mitra, R., Pecoraro, R., Dauparas, J., Glasscock, C., Baker, D.
10.1101/2025.10.03.679414 — Posted: 2025-10-08

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