Channel:  Babraham Institute

157 Articles

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Chemical conversion of human conventional Pluripotent Stem Cells to Trophoblast Stem Cells
Zorzan, I., Betto, R. M., Rossignoli, G., Arboit, M., Drusin, A., Martini, P., Martello, G.
10.1101/2022.04.07.487453 — Posted: 2022-04-08
The AppNL-G-F mouse model of Alzheimer's disease is refractory to regulatory T cell treatment
Yshii, L., Mascali, L., Kouser, L., Lemaitre, P., Marino, M., Dooley, J., Burton, O., Haughton, J., Callaerts-Vegh, Z., de Strooper, B., Holt, M., Pasciuto, E., Liston, A.
10.1101/2022.03.11.483903 — Posted: 2022-03-14
The timing of differentiation and potency of CD8 effector function is set by RNA binding proteins
Petkau, G., Mitchell, T. J., Chakraborty, K., Bell, S. E., DAngeli, V., Matheson, L., Turner, D. J., Saveliev, A., Gizlenci, O., Salerno, F., Katsikis, P. D., Turner, M.
10.1101/2021.06.03.446738 — Posted: 2022-03-14
Polypyrimidine Tract Binding Protein 1 regulates the activation of mouse CD8 T cells
D'Angeli, V., Monzon-Casanova, E., Matheson, L. S., Gizlenci, O., Petkau, G., Gooding, C., Berrens, R. V., Smith, C. W. J., Turner, M.
10.1101/2022.03.03.482829 — Posted: 2022-03-04
Molecular and cognitive signatures of ageing partially restored through synthetic delivery of IL2 to the brain
Lemaitre, P., Tareen, S., Pasciuto, E., Mascali, L., Martirosyan, A., Callaerts-Vegh, Z., Dooley, J., Holt, M., Yshii, L., Liston, A.
10.1101/2022.03.01.482519 — Posted: 2022-03-04
Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation
Yshii, L., Pasciuto, E., Bielefeld, P., Mascali, L., Lemaitre, P., Marino, M., Dooley, J., Kouser, L., Verschoren, S., Lagou, V., Kemps, H., Gervois, P., de Boer, A., Burton, O., Wahis, J., Tareen, S., Roca, C., Singh, K., Whyte, C., Kerstens, A., Callaerts-Vegh, Z., Poovathingal, S., Prezzemolo, T., Wierda, K., Dashwood, A., Xie, J., Van Wonterghem, E., Creemers, E., Aloulou, M., Gsell, W., Abiega, O., Munck, S., Vandenbroucke, R., Lemmens, R., De Strooper, B., Van Den Bosch, L., Himmelreich, U., Fitzsimons, C. P., Holt, M., Liston, A.
10.1101/2022.02.28.482297 — Posted: 2022-03-02
Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming
Chondronasiou, D., Gill, D., Mosteiro, L., Urdinguio, R. G., Berenguer, A., Aguilera, M., Durand, S., Aprahamian, F., Nirmalathasan, N., Abad, M., Martin-Herranz, D. E., Stephan-Otto Attolini, C., Prats, N., Kroemer, G., Fraga, M. F., Reik, W., Serrano, M.
10.1101/2022.01.20.477063 — Posted: 2022-01-21
H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeller function
Li, J., Bergmann, L., Rafael de Almeida, A., Webb, K. M., Gogol, M. M., Voigt, P., Liu, Y., Liang, H., Smolle, M. M.
10.1101/2021.02.26.432832 — Posted: 2022-01-20
Plasma cell maintenance and antibody secretion are under the control of Sec22b-mediated regulation of organelle dynamics
Bonaud, A., Gargowitsch, L., Gilbert, S., Rajan, E., Canales-Herrerias, P., Stockholm, D., Rahman, N., Collins, M., Hill, D. L., Alloatti, A., Alouche, N., Balor, S., Soldan, V., Gillet, D., Barbier, J., Bachelerie, F., Smith, K. G. C., Bruhns, P., Amigorena, S., Balabanian, K., Linterman, M. A., Peden, A., Espeli, M.
10.1101/2022.01.14.476154 — Posted: 2022-01-15
Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function
Ravichandran, M., Rafalski, D., Ortega-Recalde, O., Davies, C. I., Glanfield, C. R., Kotter, A., Misztal, K., Wang, A. H., Wojciechowski, M., Razew, M., Mayyas, I. M., Kardailsky, O., Schwarz, U., Zembrzycki, K., Morison, I. M., Helm, M., Weichenhan, D., Jurkowska, R. Z., Krueger, F., Plass, C., Zacharias, M., Hore, T. A., Bochtler, M., Jurkowski, T. P.
10.1101/2021.12.29.474486 — Posted: 2021-12-30

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