Channel:  Francis Crick Institute

1,348 Articles

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iSBEM: An Open-Source Workflow for Automated ROI Targeting in Volume Electron Microscopy
Ronchi, P., Ross, G., Burrell, A., de Folter, J., Klenz, Y., Darif, N., Young, F., Lawson, M., Albers, J., Pietz, T., Frischknecht, F., Duke, E., Roufosse, C., Collinson, L., Strange, A., Schwab, Y.
10.64898/2026.06.05.730298 — Posted: 2026-06-06
FIKK1, a member of the FIKK kinase family, phosphorylates VAR2CSA and regulates adhesion of Plasmodium falciparum-infected erythrocytes to the placental receptor CSA
Gamain, B., Semblat, J.-P., Eavis, H., Belda, H., Hamelin, R., Paquereau, C.-E., Doerig, C., Treeck, M., Dorin-Semblat, D.
10.64898/2026.03.23.713582 — Posted: 2026-06-05
Topology-aware reconstruction of cellular state landscapes from microscopy using self-supervised learning
Messori, E., Taha, D. M., Fournier, L., Foix Romero, A., Uhlmann, V., Frossard, P., Vincent-Cuaz, C., Patani, R., Luisier, R.
10.64898/2026.05.30.728966 — Posted: 2026-06-03
HKDC1 contributes to aberrant lysosome-mitochondria contact in Niemann-Pick disease type C
Pastore, R., Stanley, J., Kiraly, S., Dubois, C., Monfregola, J., de Luca, A., Guerra, G., Skehel, M., Ballabio, A., Platt, F. M., Eden, E. R.
10.64898/2026.06.01.729255 — Posted: 2026-06-02
GROQ-seq Datasets Across Transcription Factors (LacI, RamR, VanR), T7 RNA Polymerase and TEV Protease
Spinner, A., Sreenivasan, S., McLellan, J. R., Ikonomova, S. P., Cortade, D. L., dOelsnitz, S., Sheldon, K., Vasilyeva, O. B., Alperovich, N. Y., Chadha, A., Nematollahi, L., Dhroso, A., Sisson, Z., Densmore, D., Hudson, C. M., DeBenedictis, E., Kelly, P. J., Reider Apel, A., Ross, D., Baranowski, C.
10.64898/2026.04.15.718744 — Posted: 2026-05-29
CDKL5 phosphorylates neuronal ELAVL proteins to promote mRNA binding, protein synthesis and visual cortex development
Mihaylov, S. R., Lopes, A. T., Silvestre, M., Bianchini, G., Flynn, H. R., Huseynova, A., Strohbuecker, S., Griffith, L., Militti, C., Baltussen, L. L., Yuan, X., Morel, G., Claxton, S., Dempster, K., Lee, F. C. Y., Kanca, O., Köhn, M., Skehel, M., Ule, J., Iacaruso, F., Ultanir, S. K.
10.64898/2026.04.07.716766 — Posted: 2026-05-29
Lineage-specific retrotransposon co-option reveals a conserved ASH2L isoform as an epigenetic primer of developmental gene promoters
Elgood Hunt, E., Vivori, C., Mitter, R., Hannah Johnkingsly Jebaraj, J., Agnadottir, V., Delas, J., Serna Morales, E., Frith, T., Skehel, M., Elosegui-Artola, A., Briscoe, J., van Werven, F.
10.64898/2026.02.25.707914 — Posted: 2026-05-27
Endolysosomal damage promotes intraluminal protein condensate formation that limits cytosolic leakage
LI, X., Zhang, Y., ZHAO, K., Chen, G., Cui, D., Nikan, M., Young, S., Bennett, F., Seth, P. P., Ni, T., Gutierrez, M. G., Jiang, H.
10.64898/2026.05.25.726725 — Posted: 2026-05-25
Asymmetric Contrastive Objectives for Efficient Phenotypic Screening
Nightingale, L., Tuersley, J., Warchal, S., Cairoli, A., Howes, J., Shand, C., Powell, A., Green, D., Strange, A., Howell, M.
10.1101/2024.04.19.590313 — Posted: 2026-05-22
Discovery of a sulfotyrosine-motif in the human TrkB extracellular domain required for agonist activation
Briggs, D. C., Duffy, R. T., Ateaque, S., Maslen, S., Naharaj, H., Barde, Y.-A., DiStefano, P. S., Lindsay, R. M., Armstrong, P. C., Peach, C. J., McDonald, N. Q.
10.64898/2026.05.19.725324 — Posted: 2026-05-21

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