Channel:  Francis Crick Institute

1,327 Articles

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Distinct functions of PBRM1 and BAP1 reconcile the course of kidney cancer evolution and disease progression
Deng, D., Feng, H., Fendler, A., Dovga, Y., Byrne, F., Spencer, C., Martin, A., Sanroman, A. F., Bouricha, O., Shepherd, S. T. C., Fu, H., Pallikonda, H., Lobon, I., Mulder, K., Guo, Q., Elphick, M., Wang, J., Franz, A., Ben-Akinduro, S., Cattin, A.-L., Tippu, Z., Ibarzo Yus, B., Barber, T., Hepworth, S., Symons, I., Edmonds, K., Carlyle, E., Modi, A., Korteweg, J., Schneider-Santos, A., Bickley, L., Larkin, J., Rudman, S., Bex, A., Turajlic, S.
10.64898/2026.04.30.721837 — Posted: 2026-05-03
In situ cryo-ET defines the ultrastructure of ER exit sites in human cells
Downes, K. W., Flood, J. R., Nans, A., Van der Verren, S. E., Audhya, A., Zanetti, G.
10.1101/2025.07.29.667472 — Posted: 2026-04-29
Extrafollicular plasma cells disable dendritic cell-T-cell priming in tumor-draining lymph nodes
Alberts, E., Boulat, V., Hung, M. S., Xu, A. Q., Quist, J., Li, M., Liu, F., Wall, I., Verghese, G., Brundin, C. A., Bhalla, A., Jonsson, M., Castellanos, C., Rosekilly, J., GILLETT, C., Staaf, J., e Sousa, C. R., Karagiannis, S., Grigoriadis, A., Calado, D. P.
10.64898/2026.04.20.719651 — Posted: 2026-04-22
Lack of effect of physiological oxidative stress on N-terminal cysteine dependent proteolysis
Tian, Y.-M., Kim, H., Ratcliffe, P., Keeley, T. P.
10.64898/2026.04.20.719627 — Posted: 2026-04-22
Booster vaccination improves the durability of antibody-secreting plasma cells
Xu, A. Q., Hung, M. S., Chen, B., Sopena, M. L., Chakravarty, P., Camara, A., Calado, D. P.
10.64898/2026.04.18.719387 — Posted: 2026-04-22
Molecular determinants of cotranslational chaperone recruitment to nascent p53
Karpauskaite, L., Voisin, T. B., Maslen, S. L., Kent, L., Pellowe, G. A., Skehel, M., Balchin, D.
10.64898/2026.04.17.719227 — Posted: 2026-04-21
Histidine exchange sustains LAT1 activity and proliferation in glutamine-addicted breast cancers.
Gjelaj, E., Driscoll, P., Mahmood, A., Tarrago-Celada, J., Kossifos, M., Sesay, S., MacRae, J. I., Yuneva, M.
10.64898/2026.04.15.716193 — Posted: 2026-04-19
Phosphoregulated SMCR8-FIP200 interaction connects the ALS/FTD-linked C9orf72 complex to autophagy initiation and mitochondrial quality control
Wang, J., Davis, C., Kunzelmann, S., Maslen, S., Kelly, G., Skehel, M., Schreiber, A.
10.64898/2026.04.16.718395 — Posted: 2026-04-18
Pathogenic Keratinocyte States and Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa
Du-Harpur, X., Ganier, C., Mazin, P., Cheshire, C., Gabriel, J. A., Rashidghamat, E., Luscombe, N. M., Lynch, M. D., Watt, F. M.
10.1101/2025.11.11.682326 — Posted: 2026-04-17
The Alzheimer's disease neurodegenerative cascade reconstructed in human L2/3 excitatory neurons
Zielonka, M., Mallach, A., De Strooper, B., Fiers, M.
10.64898/2026.04.14.718430 — Posted: 2026-04-15

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