Channel:  Francis Crick Institute

1,302 Articles

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A DNA foundation model predicts osteoporosis risk genes without proximity bias
Regep, C., Kapourani, C.-A., Sofyali, E., Dobrowolska, A., Loukas, G., Anighoro, A., Canale, E., Gross, T., Licciardello, M., Gupta, R., Maciuca, S., Desai, T., Del Vecchio, A., Field, C., Gemayel, K., Javer, A., Zhang, Z., Tsujikawa, R., Inoue, F., Hessel, E., Taylor-King, J., Whittaker, J., Roblin, D., McIntyre, R., Edwards, L.
10.64898/2026.03.09.707383 — Posted: 2026-03-12
A divergent Plasmodium NEK4 acts as a key regulator driving the early events of meiosis
Yanase, R., Hair, M., Zeeshan, M., Ferguson, D. J. P., Brady, D., Pasquarello, C., Bottrill, A., Bhanvadia, S., Neal, A., Tromer, E. C., Le Roch, K. G., Hainard, A., Holder, A. A., Vaughan, S., Guttery, D. S., Tewari, R.
10.1101/2025.11.21.689802 — Posted: 2026-03-12
Inferring state-dependent functional circuit motifs using higher-order interactions analysis
Rashid Shomali, S., Rasuli, S. N., Shimazaki, H., Sadeh, S.
10.64898/2026.03.09.710501 — Posted: 2026-03-11
Balanced contractility and adhesion drive polarization in a minimal elastic actomyosin network
Messi, Z., Raynaud, F., Goehring, N. W., Verkhovsky, A. B.
10.1101/2025.08.26.672435 — Posted: 2026-03-10
Control of cellular cortical tension and shape by RhoGTPase signalling
Bohec, P., Khoromskaia, D., Kelkar, M., Ferber, E., Duprez, G., Lavoie, G., Valon, L., Roux, P. P., Salbreux, G., Charras, G.
10.64898/2025.12.15.694413 — Posted: 2026-03-10
Meiotic cohesin Rec8 imposes fitness costs on fission yeast gametesfavoring the evolution of parental bias in gene expression
Martins, C., Booth, H., Salat Canela, C., Hadjivasiliou, Z., Vjestica, A.
10.64898/2026.03.07.710300 — Posted: 2026-03-08
A stable subgenomic reporter coronavirus enables transcriptional profiling of bystander cells.
Gilbride, C., Hemsley-Taylor, J., Nunes, C., Penn, R., Boot, J., Pieris, N., Tripathy, R., Yang, Z., Hutchinson, M., Platt, O. K., Ulferts, R., Mitter, R., Strom, M., Santos, N. B., Bauer, D. L., Mears, H. V.
10.64898/2026.02.27.708290 — Posted: 2026-03-03
Bacterial whole-cell biosensors illuminate spatially variable sialic acid availability within the inflamed mammalian gut
Carreno, D., Robinson, C. M., Jackson, R., Li, P., Nunes, V., Palma-Duran, S. A., Nye, E., MacRae, J. I., Riglar, D. T.
10.1101/2024.10.23.619804 — Posted: 2026-02-28
Glucose concentration of neuronal media formulations influences PINK1-dependent mitophagy in human iNeurons
O'Callaghan, B., Melandri, D., Soltic, D., Cosker, K., Soutar, M. P. M., Evans, J. R., Lucas-Clarke, H., Robin, J., Gandhi, S., Birsa, N., Arber, C., Wray, S., Plun-Favreau, H.
10.1101/2025.04.01.646648 — Posted: 2026-02-26
An injectable soft implant for long-acting, reversible, ultra-stable release of therapeutics
Stevens, M. M., Kütahya, C., Panariello, L., Najer, A., Rizou, T., Shamsabadi, A., Brachi, G., Peeler, D. J., Zharova, L., Fernandez Debets, T. F. F., Peschke, P., Constantinou, A. P., Xie, R., Cheng, Y., Burdis, R., Suarez-Bonnet, A., Cihova, M., Yeow, J., Schaufelberger, F., Malanchi, I.
10.64898/2026.02.25.707913 — Posted: 2026-02-26

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