Channel:  Francis Crick Institute

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

1024 Articles

PDZ-directed substrate recruitment is the primary determinant of specific 4E-BP1dephosphorylation by PP1-Neurabin
Fedoryshchak, R. O., El-Bouri, K., Joshi, D., Mouilleron, S., Treisman, R.
10.1101/2024.09.23.614477 — Posted: 2024-09-23
Divergent Plasmodium protein kinases drive MTOC, kinetochore and axoneme organisation in male gametogenesis
Yanase, R., Zeeshan, M., Ferguson, D. J., Markus, R., Brady, D., Bottrill, A. R., Holder, A. A., Guttery, D. S., Tewari, R.
10.1101/2024.09.22.613647 — Posted: 2024-09-22
An intrinsically disordered RNA-binding region provides local target selectivity and is essential for LARP6 function.
Capraro, F., Abis, G., Karimzadeh, M., Masino, L., Barley, A., Bui, T. T. T., Goodarzi, H., Conte, M. R., Mardakheh, F. K.
10.1101/2024.09.20.614075 — Posted: 2024-09-20
Gonadotrophs have a dual origin, with most derived from pituitary stem cells during minipuberty.
Sheridan, D., Chakravarty, P., Golan, G., Shiakola, Y., Olsen, J., Burnett, E., Galichet, C., Mollard, P., Melamed, P., Lovell-Badge, R., Rizzoti, K.
10.1101/2024.09.09.610834 — Posted: 2024-09-20
SIRPalpha+ PD-L1+ bone marrow macrophages aid AML growth by modulating T cell function
Birch, F., Gonzalez-Anton, S., Haltalli, M. L. R., Chakravarty, P., Bruno, F., Georgiou, C., Mai, C., Todd, Y., Payne, E., Blum, S., Pospori, C., Arber, C., Burt, R., Tissot, F. S., Celso, C. L.
10.1101/2024.09.15.613123 — Posted: 2024-09-19
The human ribosome modulates multidomain protein biogenesis by delaying cotranslational domain docking
Pellowe, G. A., Voisin, T. B., Karpauskaite, L., Maslen, S. L., Roeselova, A., Skehel, M., Roustan, C., George, R., Nans, A., Kjaer, S., Taylor, I. A., Balchin, D.
10.1101/2024.09.19.613857 — Posted: 2024-09-19
Asparagine availability controls B cell homeostasis
Yazicioglu, Y. F., Marin, E., Bentkowska, K., Andrew, H., Mitchell, R., Wong, Z. Y., Fergusson, J., Borsa, M., Johnstone, J. C., Ali, M., Kronsteiner, B., Furlani, I. L., MacRae, J. I., Devine, M. J., Coles, M., Buckley, C., Dunachie, S., Clarke, A.
10.1101/2023.04.03.535433 — Posted: 2024-09-17
SOX2 drives fetal reprogramming and reversible dormancy in colorectal cancer
Baulies, A., Moncho-Amor, V., Drago-Garcia, D., Kucharska, A., Chakravarty, P., Moreno-Valladares, M., Cruces-Salguero, S., Hubl, F., Hutton, C., Kim, H., Matheu, A., Lovell-Badge, R., Li, V. S. W.
10.1101/2024.09.11.612412 — Posted: 2024-09-16
An integrated stress response-independent role of GCN2 prevents excessive ribosome biogenesis and mRNA translation
Roman-Trufero, M., Kleijn, I. T., Blighe, K., Zhou, J., Saavedra-Garcia, P., Gaffar, A., Christoforou, M., Bellotti, A., Abrahams, J., Atrih, A., Lamont, D. J., Gierlinski, M., Jayaprakash, P., Michel, A. M., Aboagye, E., Yuneva, M., Masson, G. R., Shahrezaei, V., Auner, H. W.
10.1101/2024.09.10.611650 — Posted: 2024-09-13
Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer's disease through disrupted regulated intramembrane proteolysis
Ziff, O. J., Jolly, S., Casey, J. M., Granat, L., Samra, S., Seto-Salvia, N., Alatza, A., Phadke, L., Galet, B., Ravassard, P., Potier, M.-C., Fox, N. C., Hardy, J., Salih, D., Whiting, P., Ducotterd, F., Patani, R., Wray, S., Arber, C.
10.1101/2024.09.09.611621 — Posted: 2024-09-13

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