Channel: Francis Crick Institute

1103 Articles

A human induced pluripotent stem cell toolbox for studying sex chromosome effects

Meleckyte, R., Varsally, W., Zohren, J., Eriksson, J., Incitti, T., Starnes, L., Pointon, A., Hicks, R., Powell, B. E., Turner, J.

10.1101/2025.02.28.640277 — Posted: 2025-03-03

Salmonella effector kinase SteC is activated by host-mediated phosphorylation

Pillay, T. D., Lemetais, B., Huber, J., Diaz Del Olmo, I., Li, Y., Masino, L., Maslen, S., Liu, M., Esposito, D., Hinton, J. C. D., Yu, X.-J., Thurston, T. L. M., Rittinger, K.

10.1101/2025.03.01.640964 — Posted: 2025-03-02

Biochemical reconstitution of sister chromatid cohesion establishment during DNA replication

Minamino, M., Diffley, J., Uhlmann, F.

10.1101/2025.02.25.640040 — Posted: 2025-02-28

RAS-PI3K Pathway in CAFs Shapes Physicochemical Properties of Tumor ECM to Impact Tumor progression

Cuesta, C., Alcon-Perez, M., Zheng, J., Procel, N., Cota, R. R., Fennema, D., Rosell, A., Meson, D. L., Martinez-Castedo, B., Arafat, Y., Sanz-Fraile, H., Rajeeve, V., Alonso, D., Hynds, R. E., Swanton, C., Alcaraz, J., Cutillas, P., Reyes-Aldasoro, C. C., Wang, H., Castellano, E.

10.1101/2025.01.20.633776 — Posted: 2025-02-28

Charting the liver and lung metastatic niche in breast cancer

Sznurkowska, M. K., Castro-Giner, F., Krol, I., Zhang, Y., Ozimski, L. L., D'Anna, I., Ring, A., Schwab, F. D., Zhang, Y. W., Zhou, J., Saini, M., Strittmatter, K., Budinjas, S., Vujanovic, M., Kontarakis, Z., Pontecorvi, G., Albrecht, F., Mertz, K. D., Auray, G., Giachino, C., Taylor, V., Gvozdenovic, A., Kovacs, W., Malanchi, I., Frauchiger-Heuer, H., Wicki, A., Vetter, M., Ligorio, M., Aceto, N.

10.1101/2024.10.04.616491 — Posted: 2025-02-28

Retroelement co-option disrupts the cancer transcriptional programme

Loong, J., Thompson, R., Hall, C., Doglio, L., Pape, J., Kassiotis, G.

10.1101/2025.02.21.639580 — Posted: 2025-02-27

Dynamic Modeling of Cell Cycle Arrest Through Integrated Single-Cell and Mathematical Modelling Approaches

Cortes-Rios, J., Rodriguez-Fernandez, M., Sorger, P. K., Fröhlich, F.

10.1101/2025.02.20.639240 — Posted: 2025-02-26

Cryptosporidium modifies intestinal microvilli through an exported virulence factor

Rodrigues, E., Pallett, M. A., Straker, L. C., Mkandawire, T. T., Sala, K., Collinson, L., Sateriale, A.

10.1101/2025.02.25.639898 — Posted: 2025-02-25

Spatiotemporal mapping of the contractile and adhesive forces sculpting early C. elegans embryos

Yamamoto, K., Ichbiah, S., Perez, M., Borrego-Pinto, J., Delbary, F., Goehring, N., Turlier, H., Charras, G.