Channel:  Francis Crick Institute

1,137 Articles

The penetrant chordoid glioma PRKCA mutation is an oncogenic gain-of-function kinase inactivation eliciting early onset chondrosarcoma in mice.
Calleja, v., Henry, J. C., Cobbaut, M., Sewell, J., Rizzoti, K., Houghton, F., Boeing, S., Anyanwu, N., Varsani-Brown, S., Snoeks, T., Suarez-Bonnet, A., Priestnall, S. L., McDonald, N. Q., Cameron, A. J., Parker, P. J.
10.1101/2025.05.28.656646 — Posted: 2025-05-29
Gene network architecture, mutation and selection collectively drive developmental pattern evolvability and predictability
Booth, H., Hadjivasiliou, Z.
10.1101/2024.12.23.630099 — Posted: 2025-05-29
Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data
Fontaine, M., Vives, M. J. D., Saez, M., Maizels, R., Finnie, E., Briscoe, J., Rand, D. A.
10.1101/2025.05.28.656648 — Posted: 2025-05-28
Disease-attenuated pneumococcal biosynthesis gene mutants invade the mucosal epithelium and induce innate immunity
Weight, C. M., Pollara, G. M., Betts, M., Ragazzini, R., Connor, M., Ramos-Sevillano, E., Reine, J., Whelan, M., Guerra-Assuncao, J. A., Bonfanti, P., Jolly, C., Noursadeghi, M., Ferreira, D., Brown, J., Heyderman, R. S.
10.1101/2023.06.15.545009 — Posted: 2025-05-26
RAD51AP1 is a versatile RAD51 modulator
Kuhlen, L., Argunhan, B., Liang, P., Zhong, J., Masino, L., Zhang, X.
10.1101/2025.05.24.655746 — Posted: 2025-05-24
Protein Kinase C δ: a critical hub regulating macrophage immunomodulatory functions during Mycobacterium tuberculosis infection
Hazra, R., Ozturk, M., Peton, N., Ganief, T., Poswayo, S. K., Rousseau, R. P., Naidoo, S., Jones, S.-S., Savulescu, A. F., Moseki, R., Abhimanyu, A., Plessis, N. D., Blackburn, J., Mhlanga, M. M., Kahn, C. R., Brombacher, F., Wilkinson, R. J., Parihar, S. P.
10.1101/2025.05.19.653976 — Posted: 2025-05-23
Substrate heterogeneity promotes cancer cell dissemination
Dunajova, Z., Tasciyan, S., Majek, J., Merrin, J., Sahai, E., Sixt, M., Hannezo, E.
10.1101/2025.05.20.655037 — Posted: 2025-05-23
CRITICAL ROLE OF ADULT-BORN DENTATE GRANULE NEURONS IN PATTERN COMPLETION
roullet, p., Koehl, M., Delage, P., Guillemot, F., Abrous, N.
10.1101/2025.05.15.654267 — Posted: 2025-05-20
Sex-dependent neural plasticity in response to damage
Recatala-Martinez, M., Bosch, M., Gaspar, P., Mineo, A., Rios, S., Miguel-Aliaga, I., Morey, M.
10.1101/2025.05.05.652027 — Posted: 2025-05-20
The blood-brain barrier regulates brain tumour growth specifically via the SLC36 amino acid transporter Pathetic in Drosophila
Dong, Q., AlvarezOchoa, E., Kosakamoto, H., Obata, F., Alexandre, C., Cheng, L.
10.1101/2025.05.15.654179 — Posted: 2025-05-20

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