Channel:  Francis Crick Institute

1103 Articles

Molecular and cellular signatures differentiate Parkinson's disease from Parkinson's disease with dementia
Fairbrother-Browne, A., Grant-Peters, M., Brenton, J. W., Nelvagal, H., Reynolds, R. H., Lim, Y. M., Gustavsson, E. K., Macpherson, H., Montgomery, K., Evans, J. R., Hicks, A. R., Chiraki, N., Curless, T., Real, R., Xenakis, T., Houlden, H., Morris, H. R., Gandhi, S., Wood, N. W., Hardy, J., Jaunmuktane, Z., Ryten, M.
10.1101/2025.03.04.641379 — Posted: 2025-03-11
PRMT activity promotes global 3' UTR shortening in proliferating cells
Griffith, L., Capitanchik, C., Moore, S., Farcas, A., Gwynne, M., Pedna, M., Jones, D. M., Chakrabarti, A. M., Lagos, D., Urosevic, J., Lynch, J. T., Ule, J.
10.1101/2025.03.06.641848 — Posted: 2025-03-10
Engineering Cortical Networks: An Open Platform for Controlled Human Circuit Formation and Synaptic Analysis In vitro
Suklai, P., Minckley, T. F., Hagemann, C., Faber, K., Norkett, R., Guetta, L., OToole, K., Geary, B., Devine, M. J., Serio, A.
10.1101/2025.03.07.642064 — Posted: 2025-03-10
Granulocyte Derived Resistin Inhibits Monocyte Maturation and Induces Immune Suppression in CMML
Hull, N. J., Cant, R., Guest, L. A., Wang, Y.-H., Gurashi, K., Paredes, R., Huerga Encabo, H., Lin, C.-C., Tien, H.-F., Sellers, R., Sahoo, S., Bonnet, D., Selimoglu-Buet, D., Solary, E., Wiseman, D. H., Batta, K.
10.1101/2025.03.03.640303 — Posted: 2025-03-07
Mechanical fracturing of the extracellular matrix patterns the vertebrate heart
Jin Ji, C. C., Santos-Olivan, D., Ramel, M.-C., Sanchez-Posada, J., Paizakis, P., Andrews, T. G., Noel, E. S., Torres-Sanchez, A., Priya, R.
10.1101/2025.03.07.641942 — Posted: 2025-03-07
DEK::NUP214 acts as an XPO1-dependent transcriptional activator of essential leukemia genes
Kaya, F., Bewicke-Copley, F., Miettinen, J. J., Casado, P., Leddy, E., Deniz, O., Lavallee, V.-P., Philippe, C., Zheng, J., Grebien, F., Khan, N., Krizsan, S., Saad, J., Nolin-Lapalme, A., Lemieux, S., Audemard, E. O., Matthews, J., Grantham, M., Di Bella, D., Wennerberg, K., Parsons, A., Rio-Machin, A., Gribben, J., Cavenagh, J. D., Freeman, S. D., Bodor, C., Sauvageau, G., Wang, J., Llamas-Sillero, P., Cazier, J.-B., Taussig, D. C., Bonnet, D., Cutillas, P. R., Heckman, C., Fitzgibbon, J., Rouault-Pierre, K.
10.1101/2025.03.05.641116 — Posted: 2025-03-07
Predictable Engineering of Signal-DependentCis-Regulatory Elements
Cornwall-Scoones, J., Benzinger, D., Yu, T., Pezzotta, A., Sagner, A., Gerontogianni, L., Bernadet, S., Finnie, E., Boezio, G. L. M., Stuart, H. T., Melchionda, M., Inge, O. C. K., Dumitrascu, B., Briscoe, J., Delas, M. J.
10.1101/2025.03.07.642002 — Posted: 2025-03-07
Mechanism of DNA-protein crosslink bypass by CMG helicase
Kyaw, M. T., Xie, S., de Lamo Peitz, E., Yardimci, H.
10.1101/2025.03.06.641852 — Posted: 2025-03-06
CAR-SPLASH identifies nascent pre-mRNA structures implicated in kinetic coupling and alternative splicing
Shenasa, H., Fong, N., Erickson, B., Iosub, I., Ule, J., Bentley, D.
10.1101/2025.03.02.641068 — Posted: 2025-03-06
Astrocytic RNA editing regulates the host immune response to alpha-synuclein
D'Sa, K., Choi, M. L., Wagen, A. Z., Seto-Salvia, N., Kopach, O., Evans, J. R., Rodrigues, M., Lopez-Garcia, P., Lachica, J., Singh, J., Ghareeb, A., Bayne, J., Grant-Peters, M., Garcia-Ruiz, S., Chen, Z., Rodriques, S., Athauda, D., Gustavsson, E. K., Gagliano Taliun, S. A., Toomey, C., Reynolds, R. H., Young, G., Strohbuecker, S., Warner, T., Rusakov, D. A., Patani, R., Bryant, C., Klenerman, D. A., Gandhi, S., Ryten, M.
10.1101/2024.02.26.582055 — Posted: 2025-03-03

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