Channel:  Francis Crick Institute

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

925 Articles

Alpha-synuclein aggregates trigger anti-viral immune pathways and RNA editing in human astrocytes
D'Sa, K., Choi, M. L., Wagen, A. Z., Seto-Salvia, N., Kopach, O., Evans, J. R., Rodrigues, M., Lopez-Garcia, P., Ghareeb, A., Bayne, J., Grant-Peters, M., Garcia-Ruiz, S., Chen, Z., Rodriques, S., Athauda, D., Gustavsson, E., Gagliano Taliun, S. A., Reynolds, R. H., Young, G., Strohbuecker, S., Warner, T., Rusakov, D. A., Patani, R., Bryant, C., Klenerman, D. A., Gandhi, S., Ryten, M.
10.1101/2024.02.26.582055 — Posted: 2024-02-28
Evolution and inhibition of the FIKK effector kinase family in P. falciparum
Belda, H., Bradley, D., Christodoulou, E., Nofal, S. D., Broncel, M., Jones, D. A., Davies, H., Bertran, M. T., Purkiss, A. G., Ogrodowicz, R. W., Joshi, D., O'Reilly, N., Walport, L., Claessens, A., Powell, A., House, D., Kjaer, S., Landry, C. R., Treeck, M.
10.1101/2024.02.22.581535 — Posted: 2024-02-23
Large-scale visualisation of α-synuclein oligomers in Parkinson's disease brain tissue
Andrews, R., Fu, B., Toomey, C. E., Breiter, J. C., Lachica, J., Tian, R., Beckwith, J. S., Needham, L.-M., Chant, G. J., Loiseau, C., Deconfin, A., Baspin, K., Magill, P. J., Jaunmuktane, Z., Freeman, O. J., Taylor, B. J. M., Hardy, J., Lashley, T., Ryten, M., Vendruscolo, M., Wood, N. W., Weiss, L. E., Gandhi, S., Lee, S. F.
10.1101/2024.02.17.580698 — Posted: 2024-02-19
A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory target gene expression
Gaggioli, M. R., Jones, A. G., Panagi, I., Washington, E. J., Loney, R. E., Muench, J. H., Brennan, R. G., Thurston, T. L. M., Ko, D. C.
10.1101/2024.02.14.580367 — Posted: 2024-02-14
Optical tweezers reveal that PfEBA and PfRH ligands, not PfMSP1, play a central role in Plasmodium-falciparum merozoite-erythrocyte attachment
Kals, E., Kals, M., Lees, R. A., Introini, V., Kemp, A., Silvester, E., Collins, C. R., Umrekar, T., Kotar, J., Cicuta, P., Rayner, J. C.
10.1101/2024.02.13.580055 — Posted: 2024-02-13
Micromolar fluoride contamination arising from glass NMR tubes and a simple solution for biomolecular applications
Matwani, K., Cornish, J., DeBenedictis, E. A., Heller, G. T.
10.1101/2024.02.12.579991 — Posted: 2024-02-12
Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response
Jones, R. A., Cooper, F., Kelly, G., Barry, D., Renshaw, M. J., Sapkota, G., Smith, J. C.
10.1101/2024.02.10.579757 — Posted: 2024-02-12
Focal Deletions of a Promoter Tether Activate the IRX3 Oncogene in T Cell Acute Lymphoblastic Leukemia
Rahman, S., Bloye, G., Farah, N., Demeulemeester, J., Costa, J. R., O'Connor, D., Pocock, R., Turna, A., Wang, L., Lee, S., Fielding, A. K., Roels, J., Jaksik, R., Dawidowska, M., Vlierberghe, P. V., Hadjur, S., Hughes, J. R., Davies, J. O. J., Gutierrez, A., Kelliher, M. A., Loo, P. V., Dawson, M. A., Mansour, M. R.
10.1101/2024.02.06.579027 — Posted: 2024-02-08
Preservation of memory B cell homeostasis in an individual producing broadly neutralising antibodies against HIV-1
Griffith, S., Muir, L., Suchanek, O., Hope, J., Pade, C., Gibbons, J. M., Tuong, Z. K., Fung, A., Touizer, E., Rees-Spear, C., Nans, A., Roustan, C., Alguel, Y., Fink, D., Orkin, C., Deayton, J., Anderson, J., Gupta, R. K., Doores, K. J., Cherepanov, P., McKnight, A., Clatworthy, M., McCoy, L. E.
10.1101/2024.02.05.578789 — Posted: 2024-02-06
Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation
Zeeshan, M., Rashpa, R., Ferguson, D. J., Mckeown, G., Nugmanova, R., Subodhi, A. K., Beyeler, R., Pashley, S. L., Markus, R., Brady, D., Roques, M., Bottrill, A. R., Fry, A. M., Pain, A., vaughan, s., Holder, A. A., Tromer, E. C., Brochet, M., Tewari, R.
10.1101/2024.02.05.578160 — Posted: 2024-02-05

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