bioRxiv is receiving many new papers on coronavirus SARS-CoV-2.   A reminder: these are preliminary reports that have not been peer-reviewed. They should not be regarded as conclusive, guide clinical practice/health-related behavior, or be reported in news media as established information.

Channel : Francis Crick Institute

475 Articles

A suite of activity-based probes to dissect the KLK activome in drug-resistant prostate cancer
Lovell, S., Zhang, L., Kryza, T., Neodo, A., Bock, N., Williams, E. D., Engelsberger, E., Xu, C., Bakker, A. T., De Vita, E., Maneiro, M., Tanaka, R. J., Bevan, C. L., Clements, J. A., Tate, E. W.
10.1101/2021.04.15.439906 — Posted: 2021-04-15
Single-shot phase contrast microscopy using polarisation-resolved differential phase contrast
Kalita, R., Flanagan, W., Lightley, J., Kumar, S., Alexandrov, Y., Garcia, E., Hintze, M., Barkoulas, M., Dunsby, C., French, P. M. W.
10.1101/2021.04.14.437846 — Posted: 2021-04-14
Chromatin-contact atlas reveals disorder-mediated protein interactions
Rafiee, M.-r., Zagalak, J., Sidorov, S., Ule, J., Luscombe, N. M.
10.1101/2020.07.13.200212 — Posted: 2021-04-13
Single cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human specific features
Rayon, T., Maizels, R. J., Barrington, C., Briscoe, J.
10.1101/2021.04.12.439474 — Posted: 2021-04-12
Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation
McClure, A. W., Diffley, J.
10.1101/2021.04.09.439171 — Posted: 2021-04-10
Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis
Pereira, C., Arroyo-Martinez, G. A., Guo, M. Z., Kelly, E. R., Grive, K. J., Mahadevaiah, S. K., Sims, J., Faca, V. M., Tsai, C., Schiltz, C. J., Wit, N., Jacobs, H., Clark, N. L., Freire, R., Turner, J., Lyndaker, A. M., Brieno-Enriquez, M. A., Cohen, P. E., Smolka, M. B., Weiss, R. S.
10.1101/2021.04.09.439198 — Posted: 2021-04-10
Image-based deep learning reveals the responses of human motor neurons to stress and ALS
Verzat, C., Harley, J., Patani, R., Luisier, R.
10.1101/2021.04.08.439054 — Posted: 2021-04-09
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp14/nsp10 Exoribonuclease
Basier, C., Basu, S., Beale, R., Bertolin, A. P., Canal, B., Curran, J. F., Deegan, T. D., Diffley, J. F., Drury, L. S., Fujisawa, R., Howell, M., Labib, K., McClure, A. W., Milligan, J., Roberts, E., Ulferts, R., Weissmann, F., Wu, M., Zeng, J.
10.1101/2021.04.07.438812 — Posted: 2021-04-08
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp15 Endoribonuclease
Beale, R., Bertolin, A. P., Canal, B., Deegan, T. D., Diffley, J. F., Drury, L. S., Fujisawa, R., Howell, M., Labib, K., McClure, A. W., Ulferts, R., Weissmann, F., Wu, M., Zeng, J.
10.1101/2021.04.07.438811 — Posted: 2021-04-08
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp3 Papain-like Protease
Armstrong, L. A., Beale, R., Bineva-Todd, G., Canal, B., Diffley, J. F., Drury, L. S., Howell, M., Kulathu, Y., Labib, K., Lim, C. T., Milligan, J., O'Reilly, N., Ozono, E., Tan, K. W., Ulferts, R., Weissmann, F., Wu, M., Zeisner, T. U., Zeng, J.
10.1101/2021.04.07.438804 — Posted: 2021-04-08

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