Channel:  Francis Crick Institute

1,165 Articles

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Streptococcus pneumoniae accessory capsular genes modulate fitness, pathogenicity and immune evasion
Chan, J. M., Flynn, H. R., Kim, S., Demetriou, H., Ramos-Sevillano, E., Alsari, A., Roalfe, L., Ercoli, G., Kalizang'oma, A., Brown, C., Chaguza, C., French, N., Brown, J. S., Goldblatt, D., de Carvalho, L. P. S., Heyderman, R.
10.1101/2025.09.11.675585 — Posted: 2025-09-15
Investigations into fission yeast chromosome size determinants
Wu, P.-S., Fallesen, T., Uhlmann, F.
10.1101/2025.09.15.676266 — Posted: 2025-09-15
Immunogenicity and Efficacy of Digitally Immune Optimised H1N1 Vaccine Candidates in Swine and Murine Animal Models
Del Rosario, J. M. M., van Diemen, P. M., Frost, S., vishwanath, s., Sujit, S. B., Ashokan, S. K., Mollett, B. C., Ramsay, A. M., Simpson, B., Asbach, B., Carnell, G. W., Chan, A., Tonks, P., Temperton, N. J., Davies, M., McCauley, J. W., Kinsley, R., Wagner, R., Everett, H. E., Heeney, J. L.
10.1101/2025.09.12.675937 — Posted: 2025-09-14
SLFN11 restricts escape from telomere crisis to prevent alternative lengthening of telomeres
Segura-Bayona, S., Borel, V., Stanage, T. H., Maric, M., Walter, M., Oliveira, R. A., Li, S., Idilli, A. I., Peritore, M., Hewitt, G., Hekkelman, M., Snell, D. M., Jones, S. T., Cheshire, C., Elezi, A., Chakravarty, P., Mitter, R., Mikolajczak, A., Gee, H. E., Nye, E., O'Sullivan, R. J., Singhi, A. D., Brummelkamp, T. R., Cesare, A. J., Boulton, S. J.
10.1101/2025.09.10.675313 — Posted: 2025-09-10
TDP-43 loss of function drives aberrant splicing in Parkinson's disease
Brenton, J. W., Follett, J., Nirujogi, R., Toomey, C. E., Lopez-Garcia, P., Evans, J. R., Lee, Y. J., Syed, K. M., Rocamora Perez, G., Fairbrother-Browne, A., D'Sa, K., Grant-Peters, M., Lachica, J., Hicks, A. R., Wagen, A. Z., O'Callaghan, B., Macpherson, H., Montgomery, K.-a., Busquets, O., Reynolds, R. H., Garcia Ruiz, S., Cao, T., Chen, Z., Plun-Favreau, H., Wong, P. C., Farrer, M., Lashley, T., Soldner, F., Hockemeyer, D., Alessi, D., Wood, N. W., Hardy, J., Rio, D. C., Jaunmuktane, Z., Gustavsson, E. K., Gandhi, S., Ryten, M.
10.1101/2025.09.04.673943 — Posted: 2025-09-09
Critical point drying of brain tissue for X-ray phase contrast imaging
Khan, S., Albers, J., Vorobyev, A., Zhang, Y., Reichmann, J., Svetlove, A., de Marco, F., Denisova, K., Yang, Y., Seichepine, F., Douglas, J. O., Duke, E., Cloetens, P., Pacureanu, A., Schaefer, A., Bosch, C.
10.1101/2025.09.02.673701 — Posted: 2025-09-09
Near real-time data on the human neutralizing antibody landscape to influenza virus to inform vaccine-strain selection in September 2025
Kikawa, C., Huddleston, J., Loes, A. N., Turner, S. A., Lee, J., Barr, I. G., Cowling, B. J., Englund, J. A., Greninger, A. L., Harvey, R., Hasegawa, H., Ho, F., Lacombe, K., Leung, N. H., Lewis, N. S., Peck, H., Watanabe, S., Smith, D. J., Bedford, T., Bloom, J. D.
10.1101/2025.09.06.674661 — Posted: 2025-09-06
Pregranulosa cells engage a distinct transcriptional programme prior to cell-cycle dependent primordial follicle activation
Taylor, G., Frost, E. R., Crow, B. N., Radley, A., Boeing, S., Galichet, C., Bucinskaite, B., Baker, M. A., Sutherland, J. M., Lovell-Badge, R.
10.1101/2022.10.24.513438 — Posted: 2025-09-05
Lactate Blocks Tertiary Lymphoid Structure Formation by Inhibiting B Cell Chemotaxis
Calado, D. P., Boulat, V., Alberts, E., Driscoll, P. C., Hung, M. S., Cunha, A., Quist, J., Liu, F., Brundin, C. A., Bhalla, A., Avalle, L., Rosekilly, J., Ryan, L., Gillett, C., Strom, M., Poli, V., MacRae, J. I., Grigoriadis, A.
10.1101/2025.08.30.673054 — Posted: 2025-09-04
Brain-derived neurotrophic factor amplifies neuron-intrinsic programs to enhance axonal regeneration in human motor neurons
Vargas, J. N. S., Brown, A.-L., Sun, K., Hagemann, C., Geary, B., Villarroel-Campos, D., Bryce-Smith, S., Zanovello, M., Lombardo, M., Majewski, S., Tosolini, A., Secrier, M., Keuss, M. J., Serio, A., Sleigh, J. N., Fratta, P., Schiavo, G.
10.1101/2023.11.06.565775 — Posted: 2025-09-04

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