Channel:  The Howard Hughes Medical Institute (HHMI)

1,285 Articles

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Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs
Stahl, E. C., Sabo, J. K., Kang, M. H., Allen, R., Applegate, E., Kim, S. E., Kwon, Y., Seth, A., Lemus, N., Salinas-Rios, V., Soczek, K., Trinidad, M., Vo, L. T., Jeans, C., Wozniak, A., Morris, T., Kimberlin, A., Foti, T., Savage, D. F., Doudna, J. A.
10.1101/2023.04.13.536294 — Posted: 2023-05-17
Direct observation of coordinated assembly of individual native centromeric nucleosomes
Popchock, A., Larson, J., Dubrulle, J., Asbury, C. L., Biggins, S.
10.1101/2023.01.20.524981 — Posted: 2023-05-17
Overlapping representations of food and social stimuli in VTA dopamine neurons
Willmore, L., Minerva, A., Engelhard, B., McMannon, B., Oak, N., Thiberge, S., Murugan, M., Pena, C. J., Witten, I.
10.1101/2023.05.17.541104 — Posted: 2023-05-17
A developmental gradient reveals biosynthetic pathways to eukaryotic toxins in monocot geophytes
Mehta, N., Meng, Y., Zare, R. N., Kamenetsky, R., Sattely, E.
10.1101/2023.05.12.540595 — Posted: 2023-05-12
Structural snapshots of hyaluronan formation reveal principles of length control and secretion
Gorniak, I., Stephens, Z., Erramilli, S., Gawda, T., Kossiakoff, A., Zimmer, J.
10.1101/2023.05.11.540447 — Posted: 2023-05-12
Molecular features driving condensate formation and gene expression by the BRD4-NUT fusion oncoprotein are overlapping but distinct
Kosno, M., Currie, S. L., Kumar, A., Xing, C., Rosen, M. K.
10.1101/2023.05.11.540414 — Posted: 2023-05-12
Electron transport inhibition increases cellular dependence on purine transport and salvage
Wu, Z., Bezwada, D., Harris, R. C., Pan, C., Nguyen, P. T., Faubert, B., Cai, L., Cai, F., Vu, H. S., Chen, H., Martin-Sandoval, M., Do, D., Gu, W., Zhang, Y., Ko, B., Brooks, B., Kelekar, S., Zhang, Y., Zacharias, L. G., Oaxaca, K. C., Mathews, T. P., Garcia-Bermudez, J., Ni, M., DeBerardinis, R. J.
10.1101/2023.05.11.540429 — Posted: 2023-05-11
Immune-induced remodelling of mRNA structurome regulates uORF-mediated translation
Xiang, Y., Chen, T., Irving, P. S., Weeks, K., Dong, X.
10.1101/2023.05.09.540021 — Posted: 2023-05-11
Joint Generation of Protein Sequence and Structure with RoseTTAFold Sequence Space Diffusion
Lisanza, S. L., Gershon, J. M., Tipps, S. W. K., Arnoldt, L., Hendel, S., Sims, J. N., Li, X., Baker, D.
10.1101/2023.05.08.539766 — Posted: 2023-05-10
The developmental timing of spinal touch processing alterations and its relation to ASD-associated behaviors in mouse models
Tasnim, A., Alkislar, I., Hakim, R., Turecek, J., Abdelaziz, A., Orefice, L. L., Ginty, D. D.
10.1101/2023.05.09.539589 — Posted: 2023-05-09

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