Channel:  The Howard Hughes Medical Institute (HHMI)

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Reconstitution of SPO11-dependent double-strand break formation
Zheng, Z., Zheng, L., Arter, M., Liu, K., Yamada, S., Ontoso, D., Kim, S., Keeney, S.
10.1101/2024.11.20.624382 — Posted: 2024-11-21
The transcription factor GABPA is a master regulator of naive pluripotency
Zhou, C., Wang, M., Zhang, C., Zhang, Y.
10.1101/2024.11.11.623003 — Posted: 2024-11-21
Cellular behavior analysis from live-cell imaging of TCR T cell-cancer cell interactions
Verma, A., Yu, C., Bachl, S., Lopez, I., Schwartz, M. S., Moen, E., Kale, N., Ching, C., Miller, G., Dougherty, T., Pao, E., Graf, W., Ward, C., Jena, S. G., Marson, A., Carnevale, J., Van Valen, D. A., Engelhardt, B. E.
10.1101/2024.11.19.624390 — Posted: 2024-11-21
Recurrent hyper-motif circuits in developmental programs
Adler, M., Medzhitov, R.
10.1101/2024.11.20.624466 — Posted: 2024-11-20
Structures of vertebrate R2 retrotransposon complexes during target-primed reverse transcription and after second strand nicking
Thawani, A., Rodriguez-Vargas, A., Treeck, B. V., Hassan, N. T., Adelson, D. L., Nogales, E., Collins, K.
10.1101/2024.11.11.623112 — Posted: 2024-11-20
Improved protein binder design using -pairing targeted RFdiffusion
Sappington, I., Toul, M., Lee, D. S., Robinson, S. A., Goreshnik, I., McCurdy, C., Chan, T. C., Buchholz, N., Huang, B., Vafeados, D., Roullier, N., Garcia-Sanchez, M., Glögl, M., Kim, C., Watson, J. L., Torres, S. V., Verschueren, K. H. G., Verstraete, K., Hinck, C. S., Bernard-Valle, M., Coventry, B., Sims, J. N., Ahn, G., Wang, X., Hinck, A. P., Jenkins, T. P., Ruohola-Baker, H., Banik, S., Savvides, S. N., Baker, D.
10.1101/2024.10.11.617496 — Posted: 2024-11-19
ELAVL3 regulates splicing of RNAs encoding synaptic signaling proteins in D1 and D2 striatal medium spiny neurons.
Irmady, K., Scheckel, C., Singer, R. A., Carroll, T., Darnell, R. B.
10.1101/2024.11.18.622571 — Posted: 2024-11-19
A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation
Wang, Y., Zhang, Y., Leung, V., Heydari-Seradj, S., Sonmez, U., Servin-Vences, R., Lipomi, D. J., Ye, L., Patapoutian, A.
10.1101/2024.11.18.624210 — Posted: 2024-11-19
Accurate de novo design of high-affinity protein binding macrocycles using deep learning
Rettie, S., Juergens, D., Adebomi, V., Bueso, Y. F., Zhao, Q., Leveille, A., Liu, A., Bera, A., Wilms, J., Üffing, A., Kang, A., Brackenbrough, E., Lamb, M., Gerben, S., Murray, A., Levine, P., Schneider, M., Vasireddy, V., Ovchinnikov, S., Weiergräber, O., Willbold, D., Kritzer, J., Mougous, J., Baker, D., DiMaio, F., Bhardwaj, G.
10.1101/2024.11.18.622547 — Posted: 2024-11-18
Reducing functionally defective old HSCs alleviates aging-related phenotypes in old recipient mice
Wang, Y., Zhang, W., Zhang, C., Van, H. T., Seino, T., Zhang, Y.
10.1101/2024.11.09.622774 — Posted: 2024-11-17

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