Channel:  Aligning Science Across Parkinson's (ASAP)

458 Articles

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Novel green fluorescent polyamines to analyze ATP13A2 and ATP13A3 activity in the mammalian polyamine transport system
Houdou, M. C., Jacobs, N., Coene, J., Azfar, M., Vanhoutte, R., Van den Haute, C., Eggermont, J., Daniels, V., Verhelst, S. H. L., Vangheluwe, P.
10.1101/2022.12.15.520427 — Posted: 2022-12-15
Quantitative mapping of autophagic cargo during nutrient stress reveals YIPF3-YIPF4 as membrane receptors for Golgiphagy
Hickey, K. L., Swarup, S., Smith, I. R., Paoli, J. C., Paulo, J. A., Harper, J. W.
10.1101/2022.12.06.519342 — Posted: 2022-12-07
Sex-specific microglial responses to glucocerebrosidase inhibition: relevance to GBA1-linked Parkinson disease
Ciana, P., Brunialti, E., Villa, A., Toffoli, M., Lucas Del Pozo, S., Rizzi, N., Meda, C., Maggi, A. C., Schapira, A. H. V.
10.1101/2022.12.05.519143 — Posted: 2022-12-05
Rapid iPSC inclusionopathy models shed light on formation, consequence and molecular subtype of alpha-synuclein inclusions
Lam, I., Ndayisaba, A., Lewis, A. J., Fu, Y., Sagredo, G. T., Zaccagnini, L., Sandoe, J., Sanz, R. L., Vahdatshoar, A., Martin, T. D., Morshed, N., Ichihashi, T., Tripathi, A., Ramalingam, N., Oettgen-Suazo, C., Bartels, T., Schabinger, M., Hallacli, E., Jiang, X., Verma, A., Tea, C., Wang, Z., Hakozaki, H., Yu, X., Hyles, K., Park, C., Theunissen, T. W., Wang, H., Jaenisch, R., Lindquist, S., Stevens, B., Stefanova, N., Wenning, G., Luk, K. C., Sanchez Pernaute, R., Gomez-Esteban, J. C., Felsky, D., Kiyota, Y., Sahni, N., Yi, S. S., Chung, C.-Y., Stahlberg, H., Ferrer, I., Schoneberg, J., Ell
10.1101/2022.11.08.515615 — Posted: 2022-12-02
Structure of LRRK1 and mechanisms of autoinhibition and activation
Reimer, J. M., Dickey, A. M., Lin, Y. X., Abrisch, R. G., Mathea, S., Chatterjee, D., Fay, E. J., Daugherty, M. D., Reck-Peterson, S. L., Leschziner, A. E.
10.1101/2022.11.22.517582 — Posted: 2022-12-02
Temporal landscape of mitochondrial proteostasis governed by the UPRmt
Uoselis, L., Lindblom, R., Skulsuppaisarn, M., Khuu, G., Nguyen, T. N., Rudler, D. L., Filipovska, A., Schittenhelm, R. B., Lazarou, M.
10.1101/2022.11.30.518286 — Posted: 2022-11-30
Golgi-IP, a novel tool for multimodal analysis of Golgi molecular content
Fasimoye, R., Dong, W., Nirujogi, R. S., Rawat, E. S., Iguchi, M., Nyame, K., Phung, T. K., Bagnoli, E., Prescott, A. R., Alessi, D. R., Abu-remaileh, M.
10.1101/2022.11.22.517583 — Posted: 2022-11-23
Mutations in Parkinsonism-linked endocytic proteins synaptojanin1 and auxilin have synergistic effects on dopaminergic axonal pathology
Ng, X. Y., Wu, Y., Lin, Y., Yaqoob, S. M., Greene, L. E., De Camilli, P., Cao, M.
10.1101/2022.02.28.482419 — Posted: 2022-11-20
Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes
Dou, D., Smith, E. M., Evans, C. S., Boecker, C. A., Holzbaur, E. L. F.
10.1101/2022.11.14.516471 — Posted: 2022-11-14
Excessive Firing of Dyskinesia-Associated Striatal Direct Pathway Neurons is Gated By Dopamine and Excitatory Synaptic Input
Ryan, M. B., Girasole, A. E., McGregor, M. M., Brakaj, R., Paletzki, R. F., Gerfen, C. R., Nelson, A. B.
10.1101/2022.10.31.514594 — Posted: 2022-11-01

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