Channel: Aligning Science Across Parkinson's (ASAP)

390 Articles

Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse

Roosen, D. A., Landeck, N., Bonet-Ponce, L., Kluss, J., Conti, M., Smith, N., Saez-Atienzar, S., Ding, J., Beilina, A., Kumaran, R., Kaganovich, A., du Hoffmann, J., Williamson, C., Gershlick, D. C., Sampieri, L., Bleck, C. K. E., Liu, C., Bonifacino, J. S., Li, Y., Lewis, P. A., Cookson, M. R.

10.1101/830802 — Posted: 2021-09-16

Structural basis for the specificity of PPM1H phosphatase for Rab GTPases

Waschbüsch, D., Berndsen, K., Lis, P., Knebel, A., Lam, Y. P., Alessi, D. R., Khan, A. R.

10.1101/2021.02.17.431620 — Posted: 2021-08-22

Subcellular and regional localization of mRNA translation in midbrain dopamine neurons

Hobson, B. D., Kong, L., Angelo, M. F., Lieberman, O. J., Mosharov, E. V., Herzog, E., Sulzer, D., Sims, P. A.

10.1101/2021.07.30.454065 — Posted: 2021-08-01

Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at Chr16q11.2 and on the MAPT H1 allele

Soutar, M., Melandri, D., O'Callaghan, B., Annuario, E., Monaghan, A., Welsh, N., D'Sa, K., Guelfi, S., Zhang, D., Pittman, A., Trabzuni, D., Pan, K., Kia, D. A., Bictash, M., Gandhi, S., Houlden, H., Cookson, M. R., Wood, N., Singleton, A., Hardy, J., Whiting, P., Blauwendraat, C., Whitworth, A., Manzoni, C., Ryten, M., Lewis, P., Plun-Favreau, H.

10.1101/2020.01.06.896241 — Posted: 2021-07-30

Evaluation Of The Rims2 Locus As A Risk Locus For Parkinson's Disease Dementia

Tan, M., Real, R., Lawton, M., Bresner, C., Kanavou, S., Fotynie, T., Wood, N., Nalls, M. A., Williams, N., Ben-Shlomo, Y., Huw, M., Grosset, D., Hardy, J., Shoai, M., Morris, H. R.

10.1101/2021.07.26.21261131 — Posted: 2021-07-29

The Remote Assessment of Parkinsonism Supporting Ongoing Development of Interventions in Gaucher Disease - Study Protocol

Higgins, A. L., Toffoli, M., Mullin, S., Lee, C.-Y., Koletsi, S., Avenali, M., Blandini, F., Schapira, A. H. V.

10.1101/2021.07.21.21260533 — Posted: 2021-07-22

Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy

Eapen, V. V., Swarup, S., Hoyer, M. J., Paulo, J. A., Harper, J. W.

10.1101/2021.07.19.452535 — Posted: 2021-07-21

The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model

Yuste-Checa, P., Trinkaus, V. A., Riera-Tur, I., Imamoglu, R., Schaller, T., Wang, H., Dudanova, I., Hipp, M. S., Bracher, A., Hartl, F. U.

10.1101/2021.07.16.452659 — Posted: 2021-07-16

Chemically Induced Senescence in Human Stem Cell-Derived Neurons Promotes Phenotypic Presentation of Neurodegeneration

Fathi, A., Mathivanan, S., Kong, L., Petersen, A. J., Harder, C. R. K., Block, J., Miller, J. M., Bhattacharyya, A., Wang, D., Zhang, S.-C.