Channel:  Aligning Science Across Parkinson's (ASAP)

426 Articles

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The chromatin modulating NSL complex regulates genes and pathways genetically linked to Parkinsons disease
Hicks, A. R., Reynolds, R. H., O'Callaghan, B., Garcia Ruiz, S., Gil Martinez, A. L., Botia, J. A., Plun-Favreau, H., Ryten, M.
10.1101/2023.01.16.523926 — Posted: 2023-01-18
Unconventional secretion of α-synuclein mediated by palmitoylated DNAJC5 oligomers
Wu, S., Sirkis, D. W., Thomas-Wright, I., Wade-Martins, R., Schekman, R.
10.1101/2022.01.27.477991 — Posted: 2022-12-29
Serine-129 phosphorylation of α-synuclein is a trigger for physiologic protein-protein interactions and synaptic function
Parra-Rivas, L. A., Madhivanan, K., Wang, L., Boyer, N. P., Prakashchand, D. D., Aulston, B. D., Pizzo, D. P., Branes-Guerrero, K., Tang, Y., Das, U., Scott, D. A., Rangamani, P., Roy, S.
10.1101/2022.12.22.521485 — Posted: 2022-12-23
Polygenic Parkinson's disease genetic risk score as risk modifier of parkinsonism in Gaucher disease
Blauwendraat, C., Tayebi, N., Woo, G., Lopez, G., Fierro, L., Toffoli, M., Limbachiya, N., Hughes, D., Pitz, V., Patel, D., Vitale, D., Koretsky, M. J., Hernandez, D., Real, R., Alcalay, R. N., Nalls, M. A., Morris, H. R., Schapira, A. H., Balwani, M., Sidransky, E.
10.1101/2022.12.19.22280175 — Posted: 2022-12-20
Unique functional responses differentially map onto genetic subtypes of dopamine neurons
Azcorra, M., Gaertner, Z., Davidson, C., Hayes, C. K., Ramakrishnan, C., Fenno, L., Kim, Y. S., Deisseroth, K., Longnecker, R., Awatramani, R., Dombeck, D. A.
10.1101/2022.12.19.521076 — Posted: 2022-12-19
Conserved and cell type-specific transcriptional responses to IFN-γ in the ventral midbrain
Hobson, B., Stanley, A., De Los Santos, M., Culbertson, B., Mosharov, E., Sims, P., Sulzer, D.
10.1101/2022.12.14.520294 — Posted: 2022-12-17
Novel green fluorescent polyamines to analyze ATP13A2 and ATP13A3 activity in the mammalian polyamine transport system
Houdou, M. C., Jacobs, N., Coene, J., Azfar, M., Vanhoutte, R., Van den Haute, C., Eggermont, J., Daniels, V., Verhelst, S. H. L., Vangheluwe, P.
10.1101/2022.12.15.520427 — Posted: 2022-12-15
Quantitative mapping of autophagic cargo during nutrient stress reveals YIPF3-YIPF4 as membrane receptors for Golgiphagy
Hickey, K. L., Swarup, S., Smith, I. R., Paoli, J. C., Paulo, J. A., Harper, J. W.
10.1101/2022.12.06.519342 — Posted: 2022-12-07
Sex-specific microglial responses to glucocerebrosidase inhibition: relevance to GBA1-linked Parkinson disease
Ciana, P., Brunialti, E., Villa, A., Toffoli, M., Lucas Del Pozo, S., Rizzi, N., Meda, C., Maggi, A. C., Schapira, A. H. V.
10.1101/2022.12.05.519143 — Posted: 2022-12-05
Structure of LRRK1 and mechanisms of autoinhibition and activation
Reimer, J. M., Dickey, A. M., Lin, Y. X., Abrisch, R. G., Mathea, S., Chatterjee, D., Fay, E. J., Daugherty, M. D., Reck-Peterson, S. L., Leschziner, A. E.
10.1101/2022.11.22.517582 — Posted: 2022-12-02

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