Channel:  Aligning Science Across Parkinson's (ASAP)

390 Articles

Impact of 100 LRRK2 variants linked to Parkinsons Disease on kinase activity and microtubule binding
Kalogeropulou, A. F., Purlyte, E., Tonelli, F., Lange, S. M., Wightman, M., Prescott, A. R., Padmanabhan, S., Sammler, E., Alessi, D. R.
10.1101/2022.04.01.486724 — Posted: 2022-08-10
Is Tau the Initial Pathology in Dopaminergic Nigrostriatal Degeneration? Studies in Parkinsonism and Parkinson ' Disease
Chu, Y., Hirst, W. D., Federoff, H. J., Harms, A. S., Stoessl, A. J., Kordower, J. H.
10.1101/2022.08.04.502831 — Posted: 2022-08-06
Multi-ancestry genome-wide meta-analysis in Parkinson's disease
Kim, J. J., Vitale, D., Veliz-Otani, D., Lian, M., Heilbron, K., the 23andMe Research Team, , Iwaki, H., Lake, J., Solsberg, C. W., Leonard, H., Makarious, M. B., Tan, E.-K., Singleton, A. B., Bandres-Ciga, S., Noyce, A. J., Blauwendraat, C., Nalls, M. A., Foo, J. N., Mata, I.
10.1101/2022.08.04.22278432 — Posted: 2022-08-06
Large-scale biophysically detailed model of somatosensory thalamocortical circuits in NetPyNE
Borges, F. d. S., Moreira, J. V. S., Takarabe, L. M., Lytton, W. W., Dura-Bernal, S.
10.1101/2022.02.03.479029 — Posted: 2022-07-28
Nicotine-mediated rescue of α-synuclein toxicity requires synaptic vesicle glycoprotein 2
Olsen, A. L., Clemens, S. G., Feany, M. B.
10.1101/2022.07.26.501592 — Posted: 2022-07-28
Cell type directed design of synthetic enhancers
Taskiran, I. I., Spanier, K. I., Christiaens, V., Mauduit, D., Aerts, S.
10.1101/2022.07.26.501466 — Posted: 2022-07-27
Integrated multi-cohort analysis of the Parkinson's disease gut metagenome
Boktor, J. C., Sharon, G., Verhagen Metman, L. A., Hall, D. A., Engen, P. A., Zreloff, Z., Hakim, D. J., Bostick, J. W., Ousey, J., Lange, D., Humphrey, G., Ackermann, G., Carlin, M., Knight, R., Keshavarzian, A., Mazmanian, S. K.
10.1101/2022.07.20.500694 — Posted: 2022-07-21
Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation
Ren, X., Nguyen, T. N., Lam, W. K., Buffalo, C. Z., Lazarou, M., Yokom, A. L., Hurley, J. H.
10.1101/2022.07.12.499634 — Posted: 2022-07-13
Structural and functional landscape of α-synuclein fibril conformations amplified from cerebrospinal fluid
Sokratian, A., Zhou, Y., Xu, E., Viverette, E., Dillard, L., Yuan, Y., Li, J., Matarangas, A., Bouvette, J., Borgnia, M. J., Bartesaghi, A., West, A.
10.1101/2022.07.13.499896 — Posted: 2022-07-13
Mitoguardin-2 is a lipid transporter and its lipid transfer ability is required for function
Hong, Z., Adlakha, J., Guinn, E., Giska, F., Gupta, K., Melia, T., Reinisch, K. M.
10.1101/2022.07.08.499339 — Posted: 2022-07-09

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