Channel:  Francis Crick Institute

1,121 Articles

The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism
Xu, R., Jones, W., Wilcz-Villega, E., Costa, S., Rajeeve, V., Bentham, R. B., Bryson, K., Nagano, A., Yaman, B., Olendo Barasa, S., Wang, Y., Chelala, C., Cutillas, P., Szabadkai, G., Frezza, C., Bianchi, K.
10.1101/855361 — Posted: 2019-11-26
Engineering transplantable jejunal mucosal grafts using primary patient-derived organoids from children with intestinal failure
Meran, L., Massie, I., Weston, A., Gaifulina, R., Faull, P., Orford, M., Kucharska, A., Baulies, A., Hirst, E., Konig, J., Tedeschi, A. M., Pellegata, A. F., Eli, S., Snijders, A. P., Collinson, L., Thapar, N., Thomas, G., Eaton, S., Bonfanti, P., De Coppi, P., Li, V. S. W.
10.1101/854083 — Posted: 2019-11-25
Microtubule Nucleation by Single Human γTuRC in a Partly Open Asymmetric Conformation
Consolati, T., Locke, J., Roostalu, J., Asthana, J., Lim, W. M., Gannon, J., Martino, F., Costa, A., Surrey, T.
10.1101/853218 — Posted: 2019-11-23
Cyclic peptides can engage a single binding pocket through multiple, entirely divergent modes
Patel, K., Walport, L. J., Walshe, J. L., Solomon, P., Low, J. K. K., Tran, D. H., Mouradian, K. S., Silva, A. P. G., Wilkinson-White, L., Matthews, J. M., Guss, J. M., Payne, R. J., Passioura, T., Suga, H., Mackay, J. P.
10.1101/850321 — Posted: 2019-11-21
RNA modifications detection by comparative Nanopore direct RNA sequencing
Leger, A., Amaral, P. P., Pandolfini, L., Capitanchik, C., Capraro, F., Barbieri, I., Migliori, V., Luscombe, N. M., Enright, A. J., Tzelepis, K., Ule, J., Fitzgerald, T., Birney, E., Leonardi, T., Kouzarides, T.
10.1101/843136 — Posted: 2019-11-15
Integrated Genomic Analysis Reveals Key Features of Long Undecoded Transcript Isoform (LUTI)-based Gene Repression
Tresenrider, A., Jorgensen, V., Chia, M., Liao, H., van Werven, F., Unal, E.
10.1101/843458 — Posted: 2019-11-15
Escape from nonsense mediated decay associates with anti-tumor immunogenicity
Litchfield, K., Reading, J., Lim, E., Xu, H., Liu, P., Al-Bakir, M., Wong, S., Rowan, A., Funt, S., Merghoub, T., Lauss, M., Svane, I. M., Jonsson, G., Herrero, J., Larkin, J., Quezada, S. A., Hellmann, M. D., Turajlic, S., Swanton, C.
10.1101/823716 — Posted: 2019-11-14
Single-Cell Signalling Analysis of Heterocellular Organoids
Qin, X., Sufi, J., Vlckova, P., Kyriakidou, P., Acton, S. E., Li, V. S. W., Nitz, M., Tape, C. J.
10.1101/659896 — Posted: 2019-11-11
Missense variants in health and disease affect distinct functional pathways and proteomics features
Laddach, A., Ng, J. C.-F., Fraternali, F.
10.1101/512764 — Posted: 2019-11-10
Immune surveillance in clinical regression of pre-invasive squamous cell lung cancer
Pennycuick, A., Teixeira, V. H., AbdulJabbar, K., Raza, S. E. A., Lund, T., Akarca, A., Rosenthal, R., Pipinikas, C. P., Lee-Six, H., Chandrasekharan, D. P., Hynds, R. E., Gowers, K. H. C., Henry, J. Y., Denais, C., Falzon, M., Antoniou, S., Durrenberger, P. F., Furness, A., Carroll, B., Thakrar, R. M., George, P. J., Marafioti, T., Swanton, C., Thirlwell, C., Campbell, P. J., Yuan, Y., Quezada, S. A., McGranahan, N., Janes, S. M.
10.1101/833004 — Posted: 2019-11-10

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