Channel:  Francis Crick Institute

1,341 Articles

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Mutations in severe human H5N1 cases facilitate evasion from human mucus and antivirals
Sukhova, K., Yang, J., Di Maio, A., Yu, J., Oliveira, M. R., Hens, H., Sadeyen, J.-R., Bagri, S., Jones, S., Hassard, J. A., Mettier, J., Zhou, J., Srivastava, A. D., Mathur, N., Schumann, B., Haslam, S. M., Iqbal, M., Liu, Y., Peacock, T. P., Barclay, W. S., Klim, H.
10.64898/2026.07.28.740943 — Posted: 2026-07-28
TRPML1 loss drives lysosomal calcium failure and astrocyte dysfunction across Alzheimer's Disease progression
Shah, D., Desai, P., Chertavian, C., Thackray, M., Demoulin, M., Mitchener, V., Strom, M., De Strooper, B., Arancibia Carcamo, L.
10.64898/2026.07.23.740052 — Posted: 2026-07-27
Epistasis facilitates the long-term antigenic evolution of the influenza B virus hemagglutinin
Schwab, L. S. U., XIE, R., Reilly, E., Aban, M., Spirason, N., Deng, Y.-M., Shu, H., Suryadinata, R., Galiano, M., Gartner, M., Subbarao, K., Laurie, K., Rockman, S., Wheatley, A. K., Kent, S. J., Barr, I. G., Dhanasekaran, V., Koutsakos, M.
10.64898/2026.07.22.739994 — Posted: 2026-07-22
Glycogen-Dependent Metabolic Reprogramming Regulates Microglial Activation and Dysfunction in Neurodegenerative Disease
McAlister, H., Merchant, H., Mitchener, V., Gatto, N., Thackray, M., Blackburn, E., Shackleton, L., Gentry, M. S., Arancibia Carcamo, L., Lloyd, A. F.
10.64898/2026.07.13.738226 — Posted: 2026-07-16
RAS-PI3K signaling promotes myofibroblastic CAF identity and restrains an immunomodulatory stromal program
Cuesta, C., Alcon-Perez, M., Cota, R. R., Coadour, S., Zheng, J., Procel, N., Fennema, D., Rosell, A., Meson, D. L., Martinez-Castedo, B., Arafat, Y., Sanz-Fraile, H., Rajeeve, V., Alonso, D., Hynds, R. E., Swanton, C., Alcaraz, J., Cutillas, P., Reyes-Aldasoro, C. C., Wang, H., Castellano, E.
10.1101/2025.01.20.633776 — Posted: 2026-07-14
Gene Regulatory Networks Mediate Pattern Scaling in Growing Tissues
Bowen, A. E., Hadjivasiliou, Z.
10.64898/2026.07.08.737218 — Posted: 2026-07-12
Mitochondrial Optic Atrophy (OPA)1 expression regulates the injury response to neonatal hypoxia-ischaemia.
Curel, C., Jones, A., Crawford, A. H., Goikolea Vives, A., Chabrier, G., Gil, G., Oregioni, A., Southworth, R., Eykyn, T. R., Stolp, H. B., Nobeli, I., Thornton, C.
10.64898/2026.05.21.726935 — Posted: 2026-07-10
Low-abundance αSyn-112 promotes αSyn-140 aggregation in vitro and forms immunoreactive deposits in Parkinson's disease brain tissue
Röntgen, A., Fusco, G., Breiter, J., Beckwith, J. S., Lachica, J., Toomey, C. E., Singh, J., Klementieva, O., Gandhi, S., Lee, S., De Simone, A., Toprakcioglu, Z., Vendruscolo, M.
10.64898/2026.07.05.736591 — Posted: 2026-07-09
Multi-Site Reproducibility Study of 3D High-Content Analysis with Dual-View Oblique Plane Microscopy
Alexandrov, Y., Arias-Garcia, M., Bakal, C., Batlle, E., Bousgouni, V., Carragher, N., Colombelli, J., Culley, J., Curry, N., Dent, L., Dunsby, C., Dvinskikh, L., Garcia, E., Giakoumakis, N. N., Gustafsson, N., Llanses, M., Lee, M., Mandke, K. N., Marks, D., McNeish, I., Ratcliffe, C., Sahai, E., Sparks, H., Suckert, T.
10.64898/2026.06.29.735376 — Posted: 2026-07-08
Genome editing of marsupial RSX reveals conserved and divergent principles in mammalian X-inactivation
Courtois, A., Menchero, S., Ogushi, S., Varsally, W., Wood, S., Decarpentrie, F., Yoshimi, R., Shiraishi, A., Inoue, K., Abe, T., VandeBerg, J. L., Snell, D. M., Kiyonari, H., Turner, J. M. A.
10.64898/2026.07.01.735830 — Posted: 2026-07-07

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