Channel:  Francis Crick Institute

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Survival of the frequent at finite population size and mutation rate: bridging the gap between quasispecies and monomorphic regimes with a simple model
Khatri, B. S.
10.1101/375147 — Posted: 2020-02-04
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene-dose-sensitive AD-suppressor in human brain
Alic, I., Goh, P. A., Murray, A., Portelius, E., Gkanatsiou, E., Gough, G., Mok, K. Y., Koschut, D., Brunmeir, R., Yeap, Y. J., O'Brien, N. L., Groet, J., Shao, X., Havlicek, S., Dunn, N. R., Kvartsberg, H., Brinkmalm, G., Hithersay, R., Startin, C., Hamburg, S., Phillips, M., Pervushin, K., Turmaine, M., Wallon, D., Rovelet-Lecrux, A., Soininen, H., Volpi, E., Martin, J. E., Foo, J. N., Becker, D. L., Rostagno, A., Ghiso, J., Krsnik, Z., Simic, G., Kostovic, I., Mitrecic, D., LonDownS Consortium, , Francis, P. T., Blennow, K., Strydom, A., Hardy, J., Zetterberg, H., Nizetic, D.
10.1101/2020.01.29.918037 — Posted: 2020-01-31
Pyphe: A python toolbox for assessing microbial growth and cell viability in high-throughput colony screens
Kamrad, S., Rodriguez-Lopez, M., Cotobal, C., Correia-Melo, C., Ralser, M., Bahler, J.
10.1101/2020.01.22.915363 — Posted: 2020-01-23
KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity
Fournier, M., Bleuyard, J.-Y., Couturier, A. M., Ellins, J., Hester, S., Smerdon, S. J., Tora, L., Esashi, F.
10.1101/735811 — Posted: 2020-01-21
Human AKTIP interacts with ESCRT proteins and functions at the midbody in cytokinesis
Merigliano, C., Burla, R., La Torre, M., Del Giudice, S., Teo, H. L., Liew, C. W., Goh, W. I., Chojnowski, A., Olmos, Y., Chiolo, I. E., Carlton, J. G., Raimondo, D., Stewart, C. L., Rhodes, D., Wright, G. D., Burke, B., Saggio, I.
10.1101/2020.01.19.911891 — Posted: 2020-01-20
Local retinoic acid directs emergence of the extraocular muscle functional unit
Comai, G. E., Tesarova, M., Dupe, V., Rhinn, M., Vallecillo Garcia, P., da Silva, F., Feret, B., Exelby, K., Dolle, P., Carlsson, L., Pryce, B., Spitz, F., Stricker, S., Zikmund, T., Kaiser, J., Briscoe, J., Schedl, A., Ghyselinck, N. B., Schweitzer, R., Tajbakhsh, S.
10.1101/2020.01.07.897694 — Posted: 2020-01-20
Regulated repression, and not activation, governs the cell fate promoter controlling yeast meiosis
Tam, J., van Werven, F.
10.1101/2020.01.13.904912 — Posted: 2020-01-14
ARID2 deficiency promotes tumor progression and is associated with higher sensitivity to PARP inhibition in lung cancer
Moreno, T., Gonzalez-Silva, L., Monterde, B., Betancor-Fernandez, I., Revilla, C., Agraz-Doblas, A., Freire, J., Isidro, P., Quevedo, L., Montes-Moreno, S., Cereceda, L., Astudillo, A., Casar, B., Crespo, P., Morales Torres, C., Scaffidi, P., Gomez-Roman, J., Salido, E., Varela, I.
10.1101/2020.01.10.898726 — Posted: 2020-01-10
Intergenic RNA mainly derives from nascent transcripts of known genes
Agostini, F., Zagalak, J. A., Attig, J., Ule, J., Luscombe, N. M.
10.1101/2020.01.08.898478 — Posted: 2020-01-09
Identifying strategies to target the metabolic flexibility of tumours.
Mendez-Lucas, A., Lin, W., Driscoll, P. C., Legrave, N., Novellasdemunt Vilaseca, L., Xie, C., Charles, M., Wilson, Z., Jones, N. P., Rayport, S. G., Rodriguez-Justo, M., Li, V. S. W., MacRae, J. I., Hay, N., Chen, X., Yuneva, M.
10.1101/2020.01.06.896571 — Posted: 2020-01-08

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