Channel:  Francis Crick Institute

1,177 Articles

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Multi-Omic Analysis Reveals Lipid Dysregulation Associated with Mitochondrial Dysfunction in Parkinson's Disease Brain
Hallqvist, J., Toomey, C. E., Pinto, R., Wernick, A., Shahrani, M., Heales, S., Eaton, S., Mills, K., Gandhi, S., Heywood, W. E.
10.1101/2024.07.18.604051 — Posted: 2024-07-22
STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair
van den Heuvel, D., Rodriguez-Martinez, M., van der Meer, P. J., Nieto Moreno, N., Park, J., Kim, H.-S., van Schie, J. J., Wondergem, A. P., D'Souza, A., Yakoub, G., Herlihy, A., Kashyap, K., Boissiere, T., Walker, J., Mitter, R., Apelt, K., de Lint, K., Kirdok, I., Ljungman, M., Wolthuis, R. M., Cramer, P., Scharer, O. D., Kokic, G., Svejstrup, J. Q., Luijsterburg, M. S.
10.1101/2024.07.22.604575 — Posted: 2024-07-22
Structures of TGF-beta with betaglycan and the signaling receptors reveal the mechanism whereby betaglycan potentiates receptor complex assembly and signaling
Wieteska, L., Taylor, A. B., Punch, E., Coleman, J. A., Conway, I. O., Lin, Y.-F., Byeon, C.-H., Hinck, C. S., Krzysiak, T., Ishima, R., Lopez-Casillas, F., Cherepanov, P., Bernard, D. J., Hill, C. S., Hinck, A. P.
10.1101/2024.07.19.604101 — Posted: 2024-07-22
Systematic identification of Y-chromosome gene functions in mouse spermatogenesis
Subrini, J., Varsally, W., Balaguer Balsells, I., Bensberg, M., Sioutas, G., Ojarikre, O., Maciulyte, V., Gylemo, B., Crawley, K., Courtis, K., de Rooij, D. G., Turner, J. M.
10.1101/2024.07.18.604063 — Posted: 2024-07-19
Ancient Borrelia genomes document the evolutionary history of louse-borne relapsing fever
Swali, P., Booth, T., Tan, C. C. S., McCabe, J., Anastasiadou, K., Barrington, C., Borrini, M., Bricking, A., Buckberry, J., Buster, L., Carlin, R., Gilardet, A., Glocke, I., Irish, J., Kelly, M., King, M., Petchey, F., Peto, J., Silva, M., Speidel, L., Tait, F., Teoaca, A., Valoriani, S., Williams, M., Madgwick, R., Mullan, G., Wilson, L., Cootes, K., Armit, I., Gutierrez, M. G., van Dorp, L., Skoglund, P.
10.1101/2024.07.18.603748 — Posted: 2024-07-19
Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin
Carver, A., Yu, T.-Y., Yates, L., White, T., Wang, R., Lister, K., Jasin, M., Zhang, X.
10.1101/2024.07.16.603765 — Posted: 2024-07-16
PP1 PNUTS binds the restrictor and dephosphorylates RNA pol II CTD Ser5 to stimulate transcription termination
Bentley, D., Treisman, R., Erickson, B., Fong, N., Hansen, K., Sheridan, R. M., Larson, K., Saviola, A., Fedoryshchak, R., Mouilleron, S.
10.1101/2024.07.12.603302 — Posted: 2024-07-13
The bat Influenza A virus subtype H18N11 induces nanoscale MHCII clustering upon host cell attachment
Osman, M. K., Robert, J., Broich, L., Frank, D., Grosse, R., Schwemmle, M., Wrobel, A., Ciminski, K., Sieben, C., Reuther, P.
10.1101/2024.07.12.603249 — Posted: 2024-07-12
Human Gastric Multi-Regional Assembloids Favour Functional Parietal Maturation and Allow Modelling of Antral Foveolar Hyperplasia
Jones, B. C., Benedetti, G., Cala, G., Tullie, L., Simcock, I., Lutman, R., Balys, M., Amiri, R., Sufi, J., Arthurs, O., Eaton, S., Anderson, G., Elvassore, N., Li, V. S., Jones, K. D., Tape, C. J., Luni, C., Giobbe, G. G., De Coppi, P.
10.1101/2024.07.08.602480 — Posted: 2024-07-11
Sympathetic neuron-derived NPY protects from obesity by sustaining the mural progenitors of thermogenic adipocytes.
Zhu, Y., Yao, L., Gallo-Ferraz, A. L., Bombassaro, B., Simoes, M. R., Abe, I., Chen, J., Sarker, G., Ciccarelli, A., Lee, C., Martinez-Sanchez, N., Dustin, M., Anderson, K., Zhan, C., Horvath, T., Velloso, L., Kajimura, S., Domingos, A. I.
10.1101/2024.05.18.594804 — Posted: 2024-07-02

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