Channel:  The Howard Hughes Medical Institute (HHMI)

1,977 Articles

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TAK1 integrates the NLRP1 inflammasome into the innate immune response to double-stranded RNA
Corley, M. R., Hyodo, A., Toyoda, H. C., Yonemitsu, M. A., Chantharath, A., Hyde, J. L., Mitchell, P. S.
10.64898/2026.01.23.701331 — Posted: 2026-01-25
Kinetochore clustering is mediated by Mps1 phosphorylation of conserved MELT motifs in Stu1
Mallet, D. R., Jiang, M., Minnuto, G. M., Biggins, S.
10.64898/2026.01.23.701336 — Posted: 2026-01-25
Nuclear envelope budding is a non-canonical mechanism to export large transcripts in muscle cells
Zaganelli, S., Meehl, J., Abrisch, R. G., Voeltz, G. K.
10.1101/2025.04.18.649598 — Posted: 2026-01-24
Long-term post-ovariectomy mouse model recapitulates hypothalamic transcriptomic changes observed during the menopausal transition in women
Bloom, J. C. B., Torres, E., Pereira, S. A., Arvizu-Sanchez, L., Fontes, A. N., Joffe, H., Page, D. C., Navarro, V. M.
10.1101/2024.10.05.616758 — Posted: 2026-01-24
New methods for epigenetic characterization and manipulation of rare fly brain neurons
Ojha, P., Berglund, G., Yu, A. D., Rosbash, M.
10.64898/2026.01.21.700891 — Posted: 2026-01-23
Engaging Unstabilized Alkyl Radicals with Pyridoxal Radical Biocatalysis: Enantiodivergent Synthesis of Aliphatic Non-Canonical Amino Acids
Cheng, L., Chen, J., Bo, Z., Zhang, X., Liu, P., Yang, Y.
10.64898/2026.01.21.700944 — Posted: 2026-01-23
Inference of germinal center evolutionary dynamics via simulation-based deep learning
Ralph, D. K., Bakis, A. G., Galloway, J., Vora, A. A., Araki, T., Song, Y. S., DeWitt, W. S., Matsen, F. A.
10.1101/2025.08.12.669950 — Posted: 2026-01-22
Sciphy: A Bayesian phylogenetic framework using sequential genetic lineage tracing data.
Seidel, S., Zwaans, A., Regalado, S., Choi, J., Shendure, J., Stadler, T.
10.1101/2024.10.01.615771 — Posted: 2026-01-22
Strong sustained type I IFN signaling acts cell intrinsically to impair IFNγ responses and cause tuberculosis susceptibility
Fattinger, S. A., Chavez, R. A., Witt, K. C., Parisi, B., Rodriguez, J. J., Turcotte, E. A., Brydon, E. C., Fairgrieve, M. R., Dhaliwal, H., Lee, A. Y., Kotov, D. I., Vance, R. E.
10.64898/2026.01.19.700487 — Posted: 2026-01-22
High-efficiency targeted integration of extrachromosomal arrays in C. elegans using PhiC31 integrase
Rich, M. S., Pellow, R., Hefel, A., Rog, O., Jorgensen, E. M.
10.1101/2025.11.11.687718 — Posted: 2026-01-21

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