Channel:  The Howard Hughes Medical Institute (HHMI)

2,582 Articles

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Phenotypic screening of covalent compound libraries identifies chloromethyl ketone antibiotics and MiaA as a new target
Jin, Y., Jana, S., Abbasov, M., Lin, H.
10.1101/2024.01.22.576576 — Posted: 2024-01-23
FicD Sensitizes Cellular Response to Glucose Fluctuations in Mouse Embryonic Fibroblasts
Gulen, B., Kinch, L. N., Servage, K. A., Blevins, A., Stewart, N. M., Gray, H. F., Casey, A. K., Orth, K.
10.1101/2024.01.22.576705 — Posted: 2024-01-23
Sensory Input, Sex, and Function Shape Hypothalamic Cell Type Development
Kaplan, H. S., Logeman, B. L., Zhang, K., Santiago, C., Sohail, N., Naumenko, S., Ho Sui, S. J., Ginty, D. D., Ren, B., Dulac, C.
10.1101/2024.01.23.576835 — Posted: 2024-01-23
Birth of new protein folds and functions in the virome
Nomburg, J., Price, N., Doudna, J. A.
10.1101/2024.01.22.576744 — Posted: 2024-01-23
Stepwise neofunctionalization of the NF-κB family member c-Rel during vertebrate evolution
Daly, A. E., Chang, A. B., Purbey, P., Williams, K. J., Yeh, G., Li, S., Pope, S. D., Venkatesh, B., Redelings, B. D., Li, S., Nguyen, K., Rodriguez, J., Jorgensen, K., Siggers, T., Chen, L., Smale, S. T.
10.1101/2024.01.23.575293 — Posted: 2024-01-23
Gene protein sequence evolution can predict the rapid divergence of ovariole numbers in Drosophila
Whittle, C., Extavour, C. G.
10.1101/2023.09.03.556080 — Posted: 2024-01-22
Constraints on the Emergence of RNA through Non-Templated Primer Extension with Mixtures of Potentially Prebiotic Nucleotides
Jia, X., Zhang, S. J., Zhou, L., Szostak, J. W.
10.1101/2024.01.21.576316 — Posted: 2024-01-22
Accurate inference of population history in the presence of background selection
Cousins, T., Tabin, D., Patterson, N., Reich, D., Durvasula, A.
10.1101/2024.01.18.576291 — Posted: 2024-01-20
Structural Insights into the DNA-Binding Mechanism of BCL11A: The Integral Role of ZnF6
Viennet, T., Yin, M., Jayaraj, A., Kim, W., Sun, Z.-Y. J., Fujiwara, Y., Zhang, K., Seruggia, D., Seo, H.-S., Dhe-Paganon, S., Orkin, S. H., Arthanari, H.
10.1101/2024.01.17.576058 — Posted: 2024-01-20
Discovery of biaryl macrocyclic peptides with C-terminal β-amino-α-keto acid groups
Nguyen, D. T., Zhu, L., Gray, D. L., Woods, T., Padhi, C., Flatt, K. M., Mitchell, D. A., van der Donk, W. A.
10.1101/2023.10.30.564719 — Posted: 2024-01-17

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