Channel:  The Howard Hughes Medical Institute (HHMI)

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RNA Polymerase II is a Polar Roadblock to a Progressing DNA Fork
Kay, T. M., Inman, J. T., Lubkowska, L., Le, T. T., Qian, J., Hall, P. M., Wang, D., Kashlev, M., Wang, M. D.
10.1101/2024.10.11.617674 — Posted: 2024-10-13
Polyserine peptides are toxic and exacerbate tau pathology in mice
Van Alstyne, M., Nguyen, V. L., Hoeffer, C. A., Parker, R.
10.1101/2024.10.10.616100 — Posted: 2024-10-12
Intranasal hemagglutinin protein boosters induce robust mucosal immunity and cross-protection against influenza A viral challenge
Moriyama, M., Rodrigues, G., Wang, J., Hudak, A., Dong, H., Homer, R. J., Weissman, D., Ma, S., Iwasaki, A.
10.1101/2024.10.10.616291 — Posted: 2024-10-12
Bond-centric modular design of protein assemblies
Wang, S., Favor, A., Kibler, R. D., Lubner, J. M., Borst, A. J., Coudray, N., Redler, R., Chiang, H. T., Sheffler, W., Hsia, Y., Li, Z., Ekiert, D. C., Bhabha, G., Pozzo, L. D., Baker, D.
10.1101/2024.10.11.617872 — Posted: 2024-10-12
GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes
Sivadasan Bindu, D., Savage, J. T., Brose, N., Bradley, L., Dimond, K., Tan, C. X., Eroglu, C.
10.1101/2023.01.17.524433 — Posted: 2024-10-11
Tuning Insulin Receptor Signaling Using De Novo Designed Agonists
Wang, X., Cardoso, S., Cai, K., Venkatesh, P., Hung, A., Ng, M., Hall, C., Coventry, B., Lee, D., Chowhan, R., Gerben, S., Li, J., An, W., Hon, M., Accili, D., Bai, X., Choi, E., Baker, D.
10.1101/2024.10.07.617068 — Posted: 2024-10-11
Value construction through sequential sampling explains serial dependencies in decision making
Zylberberg, A., Bakkour, A., Shohamy, D., Shadlen, M. N.
10.1101/2024.01.13.575363 — Posted: 2024-10-11
A collection of split-Gal4 drivers targeting conserved signaling ligands in Drosophila
Ewen-Campen, B., Joshi, N., Herman, A. S., Thakkar, T., Zirin, J., Perrimon, N.
10.1101/2024.10.10.617664 — Posted: 2024-10-11
2.6-A resolution cryo-EM structure of a class Ia ribonucleotide reductase trapped with mechanism-based inhibitor N3CDP
Westmoreland, D. E., Feliciano, P. R., Kang, G., Cui, C., Kim, A., Stubbe, J., Nocera, D. G., Drennan, C. L.
10.1101/2024.10.09.617422 — Posted: 2024-10-10
Deep mutational scanning identifies variants of Cas1 and Cas2 that increase spacer acquisition in type II-A CRISPR-Cas systems
Hofmann, R., Herman, C., Mo, C., Mathai, J., Marraffini, L. A.
10.1101/2024.10.10.617623 — Posted: 2024-10-10

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