Channel:  The Howard Hughes Medical Institute (HHMI)

2,583 Articles

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5-azacytosine induces cytotoxicity via 5-methylcytosine depletion on chromatin-associated RNA in leukemia
Gao, B., Li, Y., Zhao, L., Zou, Z., Ma, X., Hong, J., Xiang, J., Dou, X., Yang, F.-C., Xu, M., He, C.
10.1101/2025.06.24.661348 — Posted: 2025-06-27
Prioritizing replay when future goals are unknown
Sagiv, Y., Akam, T., Witten, I., Daw, N. D.
10.1101/2024.02.29.582822 — Posted: 2025-06-27
A cell-based scrambling assay reveals phospholipid headgroup preference of TMEM16F on the plasma membrane
Teo, C. F., Tuomivaara, S. T., van Hilten, N., Crottes, D., Jan, Y. N., Grabe, M., Jan, L. Y.
10.1101/2025.06.25.661602 — Posted: 2025-06-27
Histone diversity in the archaeal domain of life
Laursen, S. p., Luger, K.
10.1101/2025.06.26.661778 — Posted: 2025-06-27
Direct observation of interdependent and hierarchical kinetochore assembly on individual centromeres
Hu, C., Popchock, A. R., Latino, A. A., Asbury, C. L., Biggins, S.
10.1101/2025.06.25.661565 — Posted: 2025-06-26
Early transcriptional signatures of MeCP2 positive and negative cells in Rett syndrome
Li, Y., Anderson, A. G., Qi, G., Wu, S.-R., Revelli, J.-P., Liu, Z., Zoghbi, H. Y.
10.1101/2025.06.26.661761 — Posted: 2025-06-26
Magnesium depletion unleashes two unusual modes of colistin resistancewith different fitness costs
Hsieh, Y.-Y. P., O'Keefe, I. P., Sun, W., Wang, Z., Yang, H., Vu, L. M., Ernst, R. K., Dandekar, A. A., Malik, H. S.
10.1101/2024.10.15.618514 — Posted: 2025-06-25
Global Neuron Shape Reasoning with Point Affinity Transformers
Troidl, J., Knittel, J., Li, W., Zhan, F., Pfister, H., Turaga, S. C.
10.1101/2024.11.24.625067 — Posted: 2025-06-25
A global map for introgressed structural variation and selection in humans
Hsieh, P., Soisangwan, N., Gordon, D., Athef Javidh, A., Harvey, W., Porubsky, D., Hoekzema, K., Baker, C., Munson, K., Kinipi, C., Leavesley, M., Brucato, N., Cox, M., RICAUT, F.-X., Gallego Romero, I., Eichler, E.
10.1101/2025.06.24.661368 — Posted: 2025-06-24
L-2-hydroxyglutarate impairs neuronal differentiation through epigenetic activation of MYC expression
Gu, W., Wang, X., Solmonson, A., Cai, L., Xiao, Y., Tasdogan, A., Franklin, J., Zhang, Y., Zhang, H., Westfall, A. K., Rowe, A., Trivedi, H., Faubert, B., Wu, Z., Sudderth, J., Zacharias, L. G., Afroze, B., Bezprozvanny, I., Sudarshan, S., Cai, F., McBrayer, S. K., Mathews, T. P., DeBerardinis, R. J.
10.1101/2025.04.16.649033 — Posted: 2025-06-24

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