Channel:  The Howard Hughes Medical Institute (HHMI)

2,326 Articles

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Discovery of the metalloenzyme IsmB revises a pathway for coprostanol formation by the human gut microbiome
Tinoco, A., Li, C., Khurana, J., Banuelos Jara, B., Plichta, D. R., Kenny, D., Xavier, R. J., Balskus, E. P.
10.64898/2025.12.29.696961 — Posted: 2025-12-30
PtdIns(3,5)P2 Is an Endogenous Ligand of STING in Innate Immune Signaling
Tan, J. X., Lv, B., Li, J., Li, T., Du, F., Chen, X., Zhang, X., Bai, X.-c., Chen, Z. J.
10.64898/2025.12.29.696917 — Posted: 2025-12-29
Structural basis for non-AUG translation regulation by 5MPs
Zottig, X., Huang, C.-Y., Seraj, Z., Grigorieff, N., Korostelev, A. A.
10.64898/2025.12.28.696766 — Posted: 2025-12-29
Human genetics implicates a BACH2-NRF2 axis in fetal hemoglobin activation
Guo, C.-J., Arora, U. P., Xu, W., Cheng, X., Cato, L. D., Li, R., Lu, H. Y., Lee, A. J., Yu, F., Agarwal, G., Lyu, P., Ye, T., Antoszewski, M., Wissman, M., Mkumbe, B. S., Ekwattanakit, S., Deelen, P., Mwita, L., Sangeda, R. Z., Suksangpleng, T., Riolueang, S., Bronson, P. G., Paul, D. S., Kawabata, E., Astle, W. J., Aguet, F., Ardlie, K., Lopez de Lapuente Portilla, A., Kang, G., Zhang, Y., Nouraie, S. M., Gordeuk, V. R., Gladwin, M. T., Garrett, M. E., Ashley-Koch, A., Telen, M. J., Custer, B., Kelly, S., DINARDO, C., Sabino, E. C., Loureiro, P., Carneiro-Proietti, A. B., Maximo, C., NHLBI T
10.1101/2023.03.24.23287659 — Posted: 2025-12-27
The organization of visual pathways in the Drosophila brain
Hoeller, J., Zhao, A., Nern, A., Rogers, E. M., Romani, S., Reiser, M. B.
10.64898/2025.12.22.696097 — Posted: 2025-12-26
Chromatin profiling for everyone: FFPE-CUTAC for the theory and practice of modern molecular biology
Xu, Y., Henikoff, S., Ahmad, K.
10.64898/2025.12.24.696395 — Posted: 2025-12-26
Influence of phosphate activation chemistry on the selection of the primordial genetic alphabet
Boskovic, F., Zhang, J., Swatiputra, A. A., Szostak, J. W.
10.64898/2025.12.23.696203 — Posted: 2025-12-25
An unusual ring pattern in the Rosβ lanthipeptide of the two-component lantibiotic roseocin
Desormeaux, E. K., Zhu, L., Luo, Y., Sareen, D., van der Donk, W. A.
10.1101/2025.10.27.684949 — Posted: 2025-12-25
Rapid fluorescence lifetime sensor development of LifeCamp enables transient and baseline absolute calcium measurements
Lodder, B., Raghubardayal, M., Ganesh, S., Cai, X., Stern, J., Sherman, M., Rosen, P., Kamath, T., Hartman, I., Siegel, M., Timmins, J., Adan, R., Andermann, M. L., Sabatini, B. L.
10.64898/2025.12.23.696288 — Posted: 2025-12-25
Genetically engineered ESC-derived embryos reveal Vinculin-dependent force responses required for mammalian neural tube closure
Prudhomme, I. S., Brooks, E. R., Taneja, N., Bhattacharya, B., LaFleche, B. J., Furuta, Y., Zallen, J. A.
10.64898/2025.12.22.696028 — Posted: 2025-12-25

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