Channel:  The Howard Hughes Medical Institute (HHMI)

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Therapeutic and vaccine-induced cross-reactive antibodies with effector function against emerging Omicron variants
Addetia, A., Piccoli, L., Case, J. B., Park, Y.-J., Beltramello, M., Guarino, B., Dang, H., Pinto, D., Scheaffer, S., Sprouse, K., Bassi, J., Silacci-Fregni, C., Muoio, F., Dini, M., Vincenzetti, L., Acosta, R., Johnson, D., Subramanian, S., Saliba, C., Giurdanella, M., Lombardo, G., Leoni, G., Culap, K., McAlister, C., Rajesh, A., Dellota, E., Zhou, J., Farhat, N., Bohan, D., Noack, J., Lempp, F. A., Cameroni, E., Whitener, B., Giannini, O., Ceschi, A., Ferrari, P., Franzetti-Pellanda, A., Biggiogero, M., Garzoni, C., Zappi, S., Bernasconi, L., Kim, M. J., Schnell, G., Czudnochowski, N., Fran
10.1101/2023.01.17.523798 — Posted: 2023-02-27
Rapid resistance profiling of SARS-CoV-2 protease inhibitors
Moghadasi, S. A., Biswas, R., Harki, D. A., Harris, R.
10.1101/2023.02.25.530000 — Posted: 2023-02-27
Human APOBEC3B promotes tumor heterogeneity in vivo including signature mutations and metastases
Durfee, C., Temiz, N. A., Levin-Klein, R., Argyris, P., Alsoe, L., Carracedo, S., Alonso, A., Proehl, J., Holzhauer, A., Seeman, Z., Lin, Y.-H. T., Vogel, R. I., Sotillo, R., Nilsen, H., Harris, R.
10.1101/2023.02.24.529970 — Posted: 2023-02-25
O-GlcNAcylation regulates neurofilament-light assembly and function and is perturbed by Charcot-Marie-Tooth disease mutations
Huynh, D. T., Hu, J., Schneider, J. R., Tsolova, K. N., Soderblom, E. J., Watson, A. J., Chi, J.-T. A., Evans, C. S., Boyce, M.
10.1101/2023.02.22.529563 — Posted: 2023-02-22
Enterovirus Evolution Reveals the Mechanism of an RNA-Targeted Antiviral and Determinants of Viral Replication
Davila-Calderon, J., Li, M.-L., Penumutchu, S., Haddad, C., Malcolm, L., Hargrove, A. E., Brewer, G., Tolbert, B. S.
10.1101/2023.02.20.529064 — Posted: 2023-02-20
Marginal specificity in protein interactions constrains evolution
Ghose, D. A., Przydzial, K. E., Mahoney, E. M., Keating, A. E., Laub, M. T.
10.1101/2023.02.18.529082 — Posted: 2023-02-19
Membrane free-energy landscapes derived from atomistic dynamics explain nonuniversal cholesterol-induced stiffening
Fiorin, G., Forrest, L. R., Faraldo-Gomez, J. D.
10.1101/2023.02.02.525347 — Posted: 2023-02-17
Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A
Harjes, S., Kurup, H. M., Rieffer, A. E., Bayarjagal, M., Filitcheva, J., Su, Y., Hale, T. K., Filichev, V. V., Harjes, E., Harris, R. S., Jameson, G. B.
10.1101/2023.02.17.528918 — Posted: 2023-02-17
Redox Regulation of m6A Methyltransferase METTL3 in Human β-cells Controls the Innate Immune Response in Type 1 Diabetes
De Jesus, D. F., Zhang, Z., Brown, N. K., Li, X., Gaffrey, M. J., Kahraman, S., Wei, J., Hu, J., Basile, G., Xiao, L., Rana, T. M., Mathews, C. E., Powers, A. C., Atkinson, M. A., Eizirik, D. L., Dhe-Paganon, S., Parent, A. V., Qian, W.-J., He, C., Kulkarni, R. N.
10.1101/2023.02.16.528701 — Posted: 2023-02-16
Regulated assembly and neurosteroid modulation constrain GABAA receptor pharmacology in vivo
Sun, C., Zhu, H., Clark, S. A., Gouaux, E.
10.1101/2023.02.16.528867 — Posted: 2023-02-16

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