Channel:  The Howard Hughes Medical Institute (HHMI)

2,312 Articles

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Flow-field inference from neural data using deep recurrent networks
Kim, T. D., Luo, T. Z., Can, T., Krishnamurthy, K., Pillow, J. W., Brody, C. D.
10.1101/2023.11.14.567136 — Posted: 2023-11-16
Engineering self-deliverable ribonucleoproteins for genome editing in the brain
Chen, K., Stahl, E. C., Kang, M. H., Xu, B., Allen, R., Trinidad, M., Doudna, J. A.
10.1101/2023.11.15.567251 — Posted: 2023-11-15
Cell type-specific effects of age and sex on human cortical neurons
Chien, J.-F., Liu, H., Wang, B.-A., Luo, C., Bartlett, A., Castanon, R., Johnson, N. D., Nery, J. R., Osteen, J., Li, J., Altshul, J., Kenworthy, M., Valadon, C., Liem, M., Claffey, N., O'Connor, C., Seeker, L. A., Ecker, J. R., Behrens, M. M., Mukamel, E. A.
10.1101/2023.11.11.566717 — Posted: 2023-11-15
Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 RNP
Chen, K., Han, H., Zhao, S., Xu, B., Yin, B., Trinidad, M., Burgstone, B. W., Murthy, N., Doudna, J. A.
10.1101/2023.11.15.566339 — Posted: 2023-11-15
Expansion of human centromeric arrays in cells undergoing break-induced replication
Showman, S., Talbert, P. B., Xu, Y., Adeyemi, R. O., Henikoff, S.
10.1101/2023.11.11.566714 — Posted: 2023-11-15
Directed Evolution of Genetically Encoded LYTACs for Cell-Mediated Delivery
Yang, J. L., Yamada-Hunter, S. A., Labanieh, L., Sotillo, E., Cheah, J. S., Roberts, D. S., Mackall, C., Ting, A. Y., Bertozzi, C.
10.1101/2023.11.14.567117 — Posted: 2023-11-15
Development of LRRK2 designed ankyrin-repeat proteins
Dederer, V., Sanz Murillo, M., Karasmanis, E. P., Hatch, K. S., Chatterjee, D., Preuss, F., Abdul Azeez, K. R., Nguyen, L. V., Galicia, C., Dreier, B., Pluckthun, A., Versees, W., Mathea, S., Leschziner, A. E., Reck-Peterson, S. L., Knapp, S.
10.1101/2023.11.14.567123 — Posted: 2023-11-15
Full-spike deep mutational scanning helps predict the evolutionary success of SARS-CoV-2 clades
Dadonaite, B., Brown, J., McMahon, T. E., Farrell, A. G., Asarnow, D., Stewart, C., Logue, J., Murrell, B., Chu, H. Y., Veesler, D., Bloom, J. D.
10.1101/2023.11.13.566961 — Posted: 2023-11-14
Structural basis for VLDLR recognition by eastern equine encephalitis virus
Yang, P., Li, W., Fan, X., Pan, J., Mann, C. J., Varnum, H., Clark, L. E., Clark, S. A., Coscia, A., Smith, K. N., Brusic, V., Abraham, J.
10.1101/2023.11.14.567065 — Posted: 2023-11-14
Serotonin transporter-dependent histone serotonylation in placenta contributes to the neurodevelopmental transcriptome
Chan, J. C., Alenina, N., Cunningham, A. M., Ramakrishnan, A., Shen, L., Bader, M., Maze, I.
10.1101/2023.11.14.567020 — Posted: 2023-11-14

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