Channel:  The Howard Hughes Medical Institute (HHMI)

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PNPLA3(148M) Promotes Hepatic Steatosis by Interfering with Triglyceride Hydrolysis Through a Gain-of-Function Mechanism
Wang, Y., Hong, S., Hudson, H., Kory, N., Kinch, L. N., Kozlitina, J., Cohen, J. C., Hobbs, H. H.
10.1101/2024.08.02.606015 — Posted: 2024-08-04
Members of an array of zinc finger proteins specify distinct Hox chromatin boundaries
Ortabozkoyun, H., Huang, P.-Y., Gonzalez-Buendia, E., Cho, H., Kim, S. Y., Tsirigos, A., Mazzoni, E. O., Reinberg, D.
10.1101/2023.04.25.538167 — Posted: 2024-08-04
Conservation of dichromatin organization along regional centromeres
Dubocanin, D., Hartley, G. A., Cortes, A. E. S., Mao, Y., Hedouin, S., Ranchalis, J. E., Agarwal, A., Logsdon, G., Munson, K. M., Real, T. D., Mallory, B. J., Eichler, E. E., Biggins, S., O'Neill, R. J., Stergachis, A. B.
10.1101/2023.04.20.537689 — Posted: 2024-08-04
Dose-dependent regulation of immune memory responses against HIV by saponin monophosphoryl lipid A nanoparticle adjuvant
Ramezani-Rad, P., Marina-Zarate, E., Maiorino, L., Myers, A., Michaels, K. K., Pires, I. S., Bloom, N. I., Lopez, P. G., Cottrell, C. A., Burton, I., Groschel, B., Pradhan, A., Stiegler, G., Budai, M., Kumar, D., Pallerla, S., Sayeed, E., Sagar, S. L., Kasturi, S. P., Van Rompay, K. K. A., Hangartner, L., Wagner, A., Burton, D. R., Schief, W. R., Crotty, S., Irvine, D. J.
10.1101/2024.07.31.604373 — Posted: 2024-08-03
Amortized template-matching of molecular conformations from cryo-electron microscopy images using simulation-based inference
Dingeldein, L., Silva-Sanchez, D., Evans, L., D'Imprima, E., Grigorieff, N., Covino, R., Cossio, P.
10.1101/2024.07.23.604154 — Posted: 2024-07-31
Nonlinear sound-sheet microscopy: imaging opaque organs at the capillary and cellular scale
Heiles, B., Nelissen, F., Terwiel, D., Park, B. M., Munoz Ibarra, E., Matalliotakis, A., Waasdorp, R., Ara, T., Barturen-Larrea, P., Duan, M., Shapiro, M. G., Gazzola, V., Maresca, D.
10.1101/2024.07.31.605825 — Posted: 2024-07-31
The big tau splice isoform resists Alzheimer's-related pathological changes
Chung, D.-e. C., Deng, X., Yalamanchili, H. K., Revelli, J.-P., Han, A. L., Tadros, B., Richman, R., Dias, M., Alavi Naini, F., Boeynaems, S., Hyman, B. T., Zoghbi, H. Y.
10.1101/2024.07.30.605685 — Posted: 2024-07-31
Diversity in Notch ligand-receptor signaling interactions
Kuintzle, R., Santat, L. A., Elowitz, M. B.
10.1101/2023.08.24.554677 — Posted: 2024-07-31
Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance
Dadonaite, B., Ahn, J. J., Ort, J. T., Yu, J., Furey, C., Dosey, A., Hannon, W. W., Baker, A. V., Webby, R. J., King, N. P., Liu, Y., Hensley, S. E., Peacock, T. P., Moncla, L. H., Bloom, J. D.
10.1101/2024.05.23.595634 — Posted: 2024-07-31
CRISPR-Cas12a bends DNA to destabilize base pairs during target interrogation
Soczek, K. M., Cofsky, J. C., Tuck, O. T., Shi, H., Doudna, J. A.
10.1101/2024.07.31.606079 — Posted: 2024-07-31

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