Channel:  The Howard Hughes Medical Institute (HHMI)

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Persistence of backtracking by human RNA polymerase II
Yang, K. B., Rasouly, A., Epshtein, V., Martinez, C., Nguyen, T., Shamovsky, I., Nudler, E.
10.1101/2023.12.13.571520 — Posted: 2023-12-19
Cell type specific enrichment of somatic aneuploidy in the mammalian brain
Mukamel, E. A., Liu, H., Behrens, M. M., Ecker, J. R.
10.1101/2023.12.18.572285 — Posted: 2023-12-19
VPS13B is localized at the cis-trans Golgi complex interface and is a functional partner of FAM177A1
Ugur, B., Schueder, F., Shin, J., Hanna, M. G., Wu, Y., Leonzino, M., Su, M., McAdow, A. R., Wilson, C. A., Postlethwait, J., Solnica-Krezel, L., Bewersdorf, J., De Camilli, P.
10.1101/2023.12.18.572081 — Posted: 2023-12-18
Imaging the voltage of neurons distributed across entire brains of larval zebrafish
Wang, Z., Zhang, J., Symvoulidis, P., Guo, W., Zhang, L., Wilson, M. A., Boyden, E. S.
10.1101/2023.12.15.571964 — Posted: 2023-12-16
Substrate-interacting pore loops of two ATPase subunits determine the degradation efficiency of the 26S proteasome
Martin, A., Lopez-Alfonzo, E. M., Saurabh, A., Zarafshan, S., Presse, S.
10.1101/2023.12.14.571752 — Posted: 2023-12-15
Connectivity underlying motor cortex activity during naturalistic goal-directed behavior
Finkelstein, A., Daie, K., Rozsa, M., Darshan, R., Svoboda, K.
10.1101/2023.11.25.568673 — Posted: 2023-12-15
Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9
Eggers, A. R., Chen, K., Soczek, K. M., Tuck, O. T., Doherty, E. E., Thornton, B. W., Xu, B., Trinidad, M. I., Doudna, J. A.
10.1101/2023.12.14.571777 — Posted: 2023-12-15
A translation-independent directed evolution strategy to engineer aminoacyl-tRNA synthetases
Soni, C., Prywes, N., Hall, M., Savage, D. F., Schepartz, A., Chatterjee, A.
10.1101/2023.12.13.571473 — Posted: 2023-12-14
MBD2 couples DNA methylation to Transposable Elements silencing during male gametogenesis.
Wang, S., Wang, M., Ichino, L., Boone, B. A., Zhong, Z., Papareddy, R. K., Lin, E. K., Yun, J., Feng, S., Jacobsen, S. E.
10.1101/2023.12.12.571353 — Posted: 2023-12-13
The juxtamembrane linker of synaptotagmin 1 regulates Ca2+ binding via liquid-liquid phase separation
Mehta, N., Mondal, S., Watson, E. T., Cui, Q., Chapman, E. R.
10.1101/2023.08.11.551903 — Posted: 2023-12-13

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