Channel:  Arc Institute

45 Articles

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Stack: In-Context Learning of Single-Cell Biology
Dong, M., Adduri, A., Gautam, D., Wu, L., Kernick, C., Coons, M. M., Chih, Y.-C., Carpenter, C., Shah, R., Ricci-Tam, C., Tung, P.-Y., Li, N., Dobin, A., Kluger, Y., Burke, D. P., Roth, T., Roohani, Y. H.
10.64898/2026.01.09.698608 — Posted: 2026-06-08
An image-based CRISPR screen reveals splicing-mediated control of HP1α condensates
Wong, M. M.-K., Zhou, S., Carpenter, C., Valbuena, R., Priyadarshini, M., Arya, A., Rizvi, A., Carswell-Crumpton, C., Wileveau, A., Lopez-Lopez, G., Tycko, J., Yao, D., Spees, K., Maynard, J., Bassik, M. C., Goodarzi, H., Sanulli, S.
10.1101/2025.09.21.676939 — Posted: 2026-05-28
A long context RNA foundation model for predicting transcriptome architecture
Saberi, A., Choi, B., Wang, S., Hernandez-Corchado, A., Naghipourfar, M., Namini, A., Ramani, V., Emad, A., Najafabadi, H. S., Goodarzi, H.
10.1101/2024.08.26.609813 — Posted: 2026-04-21
Efficient generation of epitope-targeted de novo antibodies with Germinal
Mille-Fragoso, L. S., Driscoll, C. L., Wang, J. N., Dai, H., Widatalla, T. M., Zhang, J. L., Zhang, X., Rao, B., Feng, L., Hie, B. L., Gao, X. J.
10.1101/2025.09.19.677421 — Posted: 2026-04-15
ENPP1 buffers extracellular cGAMP in brown adipose tissue to limit insulin resistance
Wang, S., Guo, Y., An, W., Lee, M., Li, Y., Sudaryo, V., Grenot, G., Skariah, G., Reghupaty, S. C., Young, S., Bai, X., Svensson, K. J., Li, L.
10.64898/2026.04.12.718013 — Posted: 2026-04-14
Systemic hypoxia suppresses solid tumor growth
Midha, A. D., Chew, B. T. L., Choi, B. M. H., Suh, J. M., Carpenter, C., Baik, A. H., Joshi, T., Blume, S. Y., Haribowo, A. G., Ruivo, P., Flanigan, W. R., Garg, A., Zhang, D. D., Subramanyam, V., Shuere, R., Seo, Y., VanBrocklin, H., Goodarzi, H., Jain, I. H.
10.64898/2026.02.09.704975 — Posted: 2026-02-10
Structure-guided design of a targeted autoantibody degrader for neurologic disease
Zimanyi, M., Dayao, M., Asencor, A. I., Kondapavulur, S., Asaki, J., McCutcheon, K., Dabaco, C., Bodansky, A., Craik, C., Pleasure, S., DeRisi, J. L., Cheng, Y., Wilson, M., Pluvinage, J. V.
10.64898/2026.02.01.703132 — Posted: 2026-02-03
Genome-wide CRISPRi screen identifies basigin loss as protective in cardiac hypoxia
Flanigan, W. R., Midha, A. D., Blume, S. Y., Marti-Mateos, Y., Costa, M. W., Huang, Y., Baik, A. H., Huynh, H., Susarla, G., Bennett, N. K., Nowak, R. A., Srivastava, D., Nakamura, K., Jain, I. H.
10.64898/2026.01.26.701810 — Posted: 2026-01-27
cyto: ultra high-throughput processing of 10x-flex single cell sequencing
Teyssier, N., Dobin, A.
10.64898/2026.01.21.700936 — Posted: 2026-01-22
scBaseCount: an AI agent-curated, uniformly processed, and autonomously updated single cell data repository
Youngblut, N. D., Carpenter, C., Nayebnazar, A., Adduri, A., Shah, R., Ricci-Tam, C., Prashar, J., Ilango, R., Teyssier, N., Konermann, S., Hsu, P., Dobin, A., Burke, D. P., Goodarzi, H., Roohani, Y. H.
10.1101/2025.02.27.640494 — Posted: 2025-11-02

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