Channel:  Arc Institute

45 Articles

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Systematic mapping of the prokaryotic noncoding sequence space with a genomic language model
Sun, G., Hudelmaier, T., Gilligan, J. C., Gonzalez, G. A., Yin, P., Wan, F., Ma, Z., Durrant, M. G., Ricci-Tam, C., Pawluk, A., Puschnik, A. S., Konermann, S., Hsu, P. D.
10.64898/2026.10.21.760802 — Posted: 2026-10-22
Predicting cell-state-specific gene regulation from DNA across species
Liu, H., Mao, S., Gallent, T., Chen, Y., Yan, Z., Vogel, I., Traunmuller, L., Zhang, R., Buenrostro, J. D., Zhou, J., Greenberg, M. E.
10.64898/2026.10.19.760026 — Posted: 2026-10-20
The adaptive architecture of tRNA dependencies across physiological tumor environments
Chen, S., Charbonneau, T., Yousefi, K., Zirak, B., Lee, S., Joshi, T., Pawluk, A., Ramani, V., Goodarzi, H.
10.64898/2026.10.08.757597 — Posted: 2026-10-09
PIE: Generalizing perturbation effects across unseen perturbations, contexts and datasets
Verma, R., Adduri, A., Bevilacqua, B., Eraslan, B., Burke, D., Goodarzi, H., Roohani, Y.
10.64898/2026.10.02.756297 — Posted: 2026-10-05
Extracellular cGAMP transmission exacerbates neuroinflammation in aging and multiple sclerosis
R. Carvalho, D., Wang, R., Liu, N., Li, Y., Younis, T., Sclip, A., Muthusamy, A., Shin, S., Pawluk, A., Goodarzi, H., Thaiss, C., Konermann, S., Li, L.
10.64898/2026.09.30.754737 — Posted: 2026-10-03
Forecasting viral evolution from phylogenetic trees
Specht, I., Park, S., Chithrananda, S., Driscoll, C. L., Brixi, G., Palacios, J. A., Hie, B. L.
10.64898/2026.08.27.741102 — Posted: 2026-09-05
Branched-chain amino acid fermentation as an alternative mammalian electron sink
Midha, A. D., Chew, B. T. L., Marti-Mateos, Y., Blume, S. Y., Flanigan, W. R., Desousa, B. R., Haribowo, A. G., Poddar, A., Chadha, S., Queliconi, B. B., Barrios, A. M., Traglia, M., Thomas, R., Suzuki, J., Kuroda, M., Altschuler, S. J., Wu, L. F., Paredes, M. F., Anthony, T. G., Lishko, P. V., Jain, I. H.
10.64898/2026.08.24.746737 — Posted: 2026-08-25
BioReason-Pro: Advancing Protein Function Prediction with Multimodal Biological Reasoning
Fallahpour, A., Seyed-Ahmadi, A., Idehpour, P., Ibrahim, O., Choi, B. M. H., Gupta, P., Naimer, J., Zhu, K., Shah, A., Ma, S., Adduri, A., Güloglu, T., Liu, N., Cui, H., Jain, A., de Castro, M., Fallahpour, A., Cembellin-Prieto, A., Stiles, J. S., Nemcko, F., Nevue, A. A., Moon, H. C., Sosnick, L., Markham, O., Duan, H., Lee, M. Y. Y., Salvador, A. F. M., Maddison, C. J., Thaiss, C. A., Ricci-Tam, C., Plosky, B. S., Burke, D. P., Hsu, P. D., Goodarzi, H., Wang, B.
10.64898/2026.03.19.712954 — Posted: 2026-07-19
The Disease Gene THAP12 is a Transcriptional Regulator of Mitochondrial ETC Complex I
Desousa, B. R., Abe, Y., Kampmann, M., Jain, I. H.
10.64898/2026.07.16.738975 — Posted: 2026-07-17
A high-level programming language for generative biology with Proto
Merchant, A., Guo, D., Viggiano, B., Brennan-Almaraz, L., Hurr, E., Mai, T., Yin, P., King, S., Ashley, E., Hie, B.
10.64898/2026.06.22.733870 — Posted: 2026-06-23

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