Channel:  Aligning Science Across Parkinson's (ASAP)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

376 Articles

Proteostasis and lysosomal repair deficits in transdifferentiated neurons of Alzheimer's disease
Chou, C.-C., Vest, R., Prado, M. A., Wilson-Grady, J., Paulo, J. A., Shibuya, Y., Moran-Losada, P., Lee, T.-T., Luo, J., Gygi, S. P., Kelly, J. W., Finley, D., Wernig, M., Wyss-Coray, T., Frydman, J.
10.1101/2023.03.27.534444 — Posted: 2025-01-13
Transgenic A53T mice have astrocytic α-synuclein aggregates in dopamine and striatal regions
Peat, C., Prasad, A., Finkelstein, D. I., Sue, C., Johnston, J., Parish, C., Thompson, L., Kirik, D., Halliday, G.
10.1101/2025.01.09.632283 — Posted: 2025-01-12
State-dependent modulation of spiny projection neurons controls levodopa-induced dyskinesia in a mouse model of Parkinson's disease
Zhai, S., Cui, Q., Wokosin, D., Sun, L., Tkatch, T., Crittenden, J. R., Graybiel, A. M., Surmeier, D. J.
10.1101/2025.01.02.631090 — Posted: 2025-01-07
GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis
Bogacki, E. C., Longmore, G., Lewis, P. A., Herbst, S.
10.1101/2025.01.01.630988 — Posted: 2025-01-01
Sub-second characterization of locomotor activities of mouse models of Parkinsonism
Berezhnoi, D., Chehade, H. D., Simms, G., Chen, L., Chu, H.-Y.
10.1101/2024.12.26.630411 — Posted: 2024-12-26
Neuronal alpha-Synuclein Disease stage progression over five years
Simuni, T., Gochanour, C., Nair, A. R., Brumm, M. C., Coffey, C., Poston, K. L., Chahine, L. M., Weintraub, D., Tanner, C. M., Gonzalez-Latapi, P., Kopil, C. M., Xiao, Y., Chowdhury, S., Dam, T., Pagano, G., Stephenson, D., Siderowf, A., Dunn, B., Marek, K., on behalf of the Parkinsons Progression Markers Initiative
10.1101/2024.12.17.24319172 — Posted: 2024-12-23
Anxa1+ dopamine neuron vulnerability defines prodromal Parkinson's disease bradykinesia and procedural motor learning impairment
Mantas, I., Contestabile, A., Skara, V., Loiseau, C., Santos, I., Cramb, K., Filograna, R., Wade-Martins, R., Magill, P., Meletis, K.
10.1101/2024.12.22.629963 — Posted: 2024-12-22
Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson's disease
Gaertner, Z., Oram, C., Schneeweis, A., Schonfeld, E., Bolduc, C., Chen, C., Dombeck, D. A., Parisiadou, L., Poulin, J. F., Awatramani, R.
10.1101/2024.06.06.597807 — Posted: 2024-12-22
The gut microbiome promotes mitochondrial respiration in the brain of a Parkinson's disease mouse model
Morais, L. H., Stiles, L., Freeman, M., Oguienko, A. D., Hoang, J. D., Jones, J., Quan, B., Devine, J., Bois, J. S., Chou, T.-F., Trinh, J., Picard, M., Gradinaru, V., Mazmanian, S. K.
10.1101/2024.12.18.629251 — Posted: 2024-12-21
A Vulnerable Subtype of Dopaminergic Neurons Drives Early Motor Deficits in Parkinson's Disease
Fushiki, A., Ng, D., Lewis, Z. R., Yadav, A., Saraiva, T., Hammand, L. A., Wirblich, C., Tasic, B., Menon, V., Silva, J. A. d., Costa, R. M.
10.1101/2024.12.20.629776 — Posted: 2024-12-21

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