Channel:  Aligning Science Across Parkinson's (ASAP)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

335 Articles

A STING-CASM-GABARAP Pathway Activates LRRK2 at Lysosomes
Bentley-DeSousa, A., Roczniak-Ferguson, A., Ferguson, S. M.
10.1101/2023.10.31.564602 — Posted: 2024-09-11
Neuronal alpha-Synuclein Disease Integrated Staging System performance in PPMI, PASADENA, and SPARK baseline cohorts.
Dam, T., Pagano, G., Brumm, M. C., Gochanour, C., Poston, K. L., Weintraub, D., Chahine, L. M., Coffey, C. S., Tanner, C. M., Kopil, C. M., Xiao, Y., Chowdhury, S., Concha-Marambio, L., DiBiaso, P., Foroud, T., Frasier, M., Jennings, D., Kieburtz, K., Merchant, K., Mollenhauer, B., Montine, T. J., Nudelman, K., Seibyl, J., Sherer, T., Singleton, A., Stephenson, D., Stern, M., Soto, C., Tolosa, E., Siderowf, A., Dunn, B., Simuni, T., Marek, K., and the Parkinson's Progression Markers Initiative
10.1101/2024.02.14.24302818 — Posted: 2024-09-10
Parkinson's Families Project: a UK-wide study of early onset and familial Parkinson's disease
Towns, C., Fang, Z.-H., Tan, M. M. X., Jasaityte, S., Schmaderer, T. M., Stafford, E. J., Pollard, M., Tilney, R., Hodgson, M., Wu, L., Labrum, R., Hehir, J., Polke, J., Lange, L. M., Schapira, A. H. V., Bhatia, K. P., Parkinsons Families Project (PFP) Study Group, , Global Parkinsons Genetics Program (GP2), , Singleton, A., Blauwendraat, C., Klein, C., Houlden, H., Wood, N. W., Jarman, P. R., Morris, H. R., Real, R.
10.1101/2023.12.05.23299397 — Posted: 2024-09-10
Presynapses are mitophagy pit stops that prevent axon degeneration
Lam, W. K., Lindblom, R. S. J., Milky, B., Mazzachi, P., Hadian-Jazi, M., Kung, C., Khuu, G., Uoselis, L., Nguyen, T. N., Skulsuppaisarn, M., Saunders, T. L., Schmidt, M. F., Dewson, G., Fogel, A. I., Bardy, C., Lazarou, M.
10.1101/2024.09.09.611943 — Posted: 2024-09-09
The mitochondrial unfolded protein response promotes senescence in human microglia by increasing S-adenosylmethionine availability for polyamine synthesis.
Perez Jimenez, M. J., Bertoli, F., Raji, H., Lam, A., Bosch, M., Weissleder, C., Nemazanyy, I., Kalb, S., Hirschberg, I., Brunetti, D., Heckenbach, I., Scheibye-Knudsen, M., Deleidi, M.
10.1101/2024.09.03.610925 — Posted: 2024-09-03
CHCHD2 mutant mice display mitochondrial protein accumulation and disrupted energy metabolism
Liao, S.-C., Kano, K., Phanse, S., Nguyen, M., Margolis, E. B., Fu, Y., Meng, J., Moutaoufik, M. T., Chatterton, Z., Aoki, H., Simms, J., Hsieh, I., Suteja, F., Sei, Y., Huang, E. J., McAvoy, K., Manfredi, G., Halliday, G., Babu, M., Nakamura, K.
10.1101/2024.08.30.610586 — Posted: 2024-09-01
Movement-related activity in the internal globus pallidus of the parkinsonian macaque
Kase, D., Zimnik, A. J., Han, Y., Harsch, D. R., Bacha, S., Cox, K. M., Bostan, A. C., Richardson, R. M., Turner, R. S.
10.1101/2024.08.29.610310 — Posted: 2024-08-30
Reconstitution of BNIP3/NIX-mediated autophagy reveals two pathways and hierarchical flexibility of the initiation machinery
Adriaenssens, E., Schaar, S., Cooke, A. S. I., Stuke, J. F. M., Sawa-Makarska, J., Nguyen, T. N., Ren, X., Schuschnig, M., Romanov, J., Khuu, G., Lazarou, M., Hummer, G., Hurley, J. H., Martens, S.
10.1101/2024.08.28.609967 — Posted: 2024-08-28
Astrocytic LRRK2 Controls Synaptic Connectivity via Regulation of ERM Phosphorylation
Wang, S., Baumert, R., Sejourne, G., Sivadasan Bindu, D., Dimond, K., Sakers, K., Vazquez, L., Moore, J. L., Tan, C. X., Takano, T., Rodriguez Salazar, M. P., Soderling, S. H., La Spada, A. R., Eroglu, C.
10.1101/2023.04.09.536178 — Posted: 2024-08-28
Behavioral screening defines three molecular Parkinsonism subgroups in Drosophila
Kaempf, N., Valadas, J. D. S., Robberechts, P., Schoovaerts, N., Praschberger, R., Ortega, A., Kilic, A., Chabot, D., Pech, U., Kuenen, S., Vilain, S., Baz, E.-S., Singh, J., Davis, J., Liu, S., Verstreken, P.
10.1101/2024.08.27.609924 — Posted: 2024-08-27

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