Channel:  Aligning Science Across Parkinson's (ASAP)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

376 Articles

State-dependent modulation of spiny projection neurons controls levodopa-induced dyskinesia in a mouse model of Parkinson's disease
Zhai, S., Cui, Q., Wokosin, D., Sun, L., Tkatch, T., Crittenden, J. R., Graybiel, A. M., Surmeier, D. J.
10.1101/2025.01.02.631090 — Posted: 2025-01-07
GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis
Bogacki, E. C., Longmore, G., Lewis, P. A., Herbst, S.
10.1101/2025.01.01.630988 — Posted: 2025-01-01
Sub-second characterization of locomotor activities of mouse models of Parkinsonism
Berezhnoi, D., Chehade, H. D., Simms, G., Chen, L., Chu, H.-Y.
10.1101/2024.12.26.630411 — Posted: 2024-12-26
Neuronal alpha-Synuclein Disease stage progression over five years
Simuni, T., Gochanour, C., Nair, A. R., Brumm, M. C., Coffey, C., Poston, K. L., Chahine, L. M., Weintraub, D., Tanner, C. M., Gonzalez-Latapi, P., Kopil, C. M., Xiao, Y., Chowdhury, S., Dam, T., Pagano, G., Stephenson, D., Siderowf, A., Dunn, B., Marek, K., on behalf of the Parkinsons Progression Markers Initiative
10.1101/2024.12.17.24319172 — Posted: 2024-12-23
Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson's disease
Gaertner, Z., Oram, C., Schneeweis, A., Schonfeld, E., Bolduc, C., Chen, C., Dombeck, D. A., Parisiadou, L., Poulin, J. F., Awatramani, R.
10.1101/2024.06.06.597807 — Posted: 2024-12-22
Anxa1+ dopamine neuron vulnerability defines prodromal Parkinson's disease bradykinesia and procedural motor learning impairment
Mantas, I., Contestabile, A., Skara, V., Loiseau, C., Santos, I., Cramb, K., Filograna, R., Wade-Martins, R., Magill, P., Meletis, K.
10.1101/2024.12.22.629963 — Posted: 2024-12-22
A Vulnerable Subtype of Dopaminergic Neurons Drives Early Motor Deficits in Parkinson's Disease
Fushiki, A., Ng, D., Lewis, Z. R., Yadav, A., Saraiva, T., Hammand, L. A., Wirblich, C., Tasic, B., Menon, V., Silva, J. A. d., Costa, R. M.
10.1101/2024.12.20.629776 — Posted: 2024-12-21
The gut microbiome promotes mitochondrial respiration in the brain of a Parkinson's disease mouse model
Morais, L. H., Stiles, L., Freeman, M., Oguienko, A. D., Hoang, J. D., Jones, J., Quan, B., Devine, J., Bois, J. S., Chou, T.-F., Trinh, J., Picard, M., Gradinaru, V., Mazmanian, S. K.
10.1101/2024.12.18.629251 — Posted: 2024-12-21
Parkinson's Disease Pathogenic Variants: Cross-Ancestry Analysis and Microarray Data Validation
Hong, S., Koretsky, M. J., Lichtenberge, J., Leonard, H., Pitz, V., Global Parkinson's Genetics Program (GP2)
10.1101/2024.12.16.24319097 — Posted: 2024-12-17
The pyrethroid insecticide deltamethrin disrupts neuropeptide and monoamine signaling pathways in the gastrointestinal tract
White, A. C., Krout, I. N., Mouhi, S., Chang, J., Kelly, S. D., Caudle, W. M., Sampson, T.
10.1101/2024.12.14.628386 — Posted: 2024-12-17

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