Channel:  Aligning Science Across Parkinson's (ASAP)

392 Articles

Cholesterol-mediated Lysosomal Dysfunction in APOE4 Astrocytes Promotes α-Synuclein Pathology in Human Brain Tissue
Mesentier-Louro, L. A., Goldman, C., Ndayisaba, A., Buonfiglioli, A., Rooklin, R. B., Schuldt, B. R., Uchitelev, A., Khurana, V., Blanchard, J. W.
10.1101/2025.02.09.637107 — Posted: 2025-02-14
Type-II kinase inhibitors that target Parkinson's Disease-associated LRRK2
Raig, N. D., Surridge, K. J., Sanz-Murillo, M., Dederer, V., Kramer, A., Schwalm, M. P., Elson, L., Chatterjee, D., Mathea, S., Hanke, T., Leschziner, A. E., Reck-Peterson, S. L., Knapp, S.
10.1101/2024.09.17.613365 — Posted: 2025-02-13
Molecularly-guided spatial proteomics captures single-cell identity and heterogeneity of the nervous system
Dutta, S., Pang, M., Coughlin, G. M., Gudavalli, S., Roukes, M. L., Chou, T.-F., Gradinaru, V.
10.1101/2025.02.10.637505 — Posted: 2025-02-11
Specific cell states underlie complex tissue regeneration in spiny mice
Rivadeneira, E. O., Allen, R. S., Adam, M., Seifert, A. W.
10.1101/2025.02.10.637521 — Posted: 2025-02-11
Aseptic, semi-sealed cranial chamber implants for chronic multi-channel neurochemical and electrophysiological neural recording in nonhuman primates
Choi, J., Amjad, U., Murray, R., Shrivastav, R., Teichert, T., Goodell, B., Schaeffer, D. J., Oluoch, J. K., Schwerdt, H. N.
10.1101/2025.02.10.636943 — Posted: 2025-02-11
EndoMAPV1, a Structural Protein Complex Landscape of Human Endosomes
Gonzalez-Lozano, M., Schmid, E. W., Whelan, E. M., Jiang, Y., Paulo, J. A., Walter, J., Harper, J. W.
10.1101/2025.02.07.636106 — Posted: 2025-02-09
A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological features
Brücke, C., Al-Azzani, M., Ramalingam, N., Ramon, M., Sousa, R. L., Buratti, F., Zech, M., Sicking, K., Amaral, L., Gelpi, E., Chandran, A., Agarwal, A., Chaves, S. R., Fernandez, C. O., Dettmer, U., Lautenschläger, J., Zweckstetter, M., Busnadiego, R. F., Zimprich, A., Outeiro, T. F.
10.1101/2024.09.23.24313864 — Posted: 2025-02-07
Micro-invasive probes for monitoring electrical and chemical neural activity in nonhuman primates
Amjad, U., Mahajan, S., Choi, J., Shrivastav, R., Murray, R., Somich, A., Coyne, O., Schwerdt, H. N.
10.1101/2025.01.30.635139 — Posted: 2025-02-05
Lysosomal Glucocerebrosidase is needed for ciliary Hedgehog signaling: A convergent pathway to Parkinsons disease
Nair, S. V., Jaimon, E., Adhikari, A., Nikoloff, J., Pfeffer, S. R.
10.1101/2025.01.20.633968 — Posted: 2025-01-21
Distinct spatially organized striatum-wide acetylcholine dynamics for the learning and extinction of Pavlovian associations
Bouabid, S., Zhang, L., Vu, M.-A. T., Tang, K., Graham, B. M., Noggle, C. A., Howe, M. W.
10.1101/2024.07.10.602947 — Posted: 2025-01-21

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