Channel:  Aligning Science Across Parkinson's (ASAP)

514 Articles

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Lysosomal TBK1 Responds to Amino Acid Availability to Relieve Rab7-Dependent mTORC1 Inhibition
Talaia, G., Bentley-DeSousa, A., Ferguson, S.
10.1101/2023.12.16.571979 — Posted: 2023-12-17
Isolation and Lipidomic Profiling of Neuronal Lipid Droplets: Unveiling the Lipid Landscape for insights into Neurodegenerative Disorders
Kumar, M., Knapp, J., Gupta, K., Ryan, T. A.
10.1101/2023.12.13.571527 — Posted: 2023-12-14
Proteomics analysis of autophagy cargos reveals distinct adaptations in PINK1 and LRRK2 models of Parkinson disease
Goldsmith, J., Ordureau, A., Boecker, C. A., Arany, M., Harper, J. W., Holzbaur, E. L.
10.1101/2022.10.03.510717 — Posted: 2023-12-13
Alpha-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinsons disease
Geibl, F. F., Henrich, M. T., Xie, Z., Zampese, E., Tkatch, T., Wokosin, D. L., Nasiri, E., Grotmann, C. A., Dawson, V. L., Dawson, T. M., Chandel, N. S., Oertel, W. H., Surmeier, D. J.
10.1101/2023.12.11.571045 — Posted: 2023-12-11
Synapsin E-domain is essential for α-synuclein function
Stavsky, A., Parra-Rivas, L. A., Tal, S., Riba, J., Madhivanan, K., Roy, S., Gitler, D.
10.1101/2023.06.24.546170 — Posted: 2023-12-07
Single cell spatial transcriptomic and translatomic profiling of dopaminergic neurons in health, aging and disease
Kilfeather, P., Khoo, J. H., Wagner, K., Liang, H., Caiazza, M.-C., An, Y., Zhang, X., Chen, X., Connor-Robson, N., Shang, Z., Wade-Martins, R.
10.1101/2023.04.20.537553 — Posted: 2023-12-04
Single-cell somatic copy number variants in brain using different amplification methods and reference genomes
Kalef-Ezra, E., Turan, Z. G., Perez-Rodriguez, D., Bomann, I., Behera, S., Morley, C., Scholz, S. W., Jaunmuktane, Z., Demeulemeester, J., Sedlazeck, F., Proukakis, C.
10.1101/2023.08.07.552289 — Posted: 2023-11-21
Dynamic refinement of behavioural structure mediates dopamine-dependent credit assignment
Tang, J. C. Y., Paixao, V., Carvalho, F., Silva, A., Klaus, A., Alves da Silva, J., Costa, R. M.
10.1101/2022.09.22.507905 — Posted: 2023-11-21
Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behavior
Vu, M.-A. T., Brown, E. H., Wen, M. J., Noggle, C. A., Zhang, Z., Monk, K. J., Bouabid, S., Mroz, L., Graham, B. M., Zhuo, Y., Li, Y., Otchy, T. M., Tian, L., Davison, I. G., Boas, D. A., Howe, M. W.
10.1101/2023.11.17.567425 — Posted: 2023-11-17
Development of LRRK2 designed ankyrin-repeat proteins
Dederer, V., Sanz Murillo, M., Karasmanis, E. P., Hatch, K. S., Chatterjee, D., Preuss, F., Abdul Azeez, K. R., Nguyen, L. V., Galicia, C., Dreier, B., Pluckthun, A., Versees, W., Mathea, S., Leschziner, A. E., Reck-Peterson, S. L., Knapp, S.
10.1101/2023.11.14.567123 — Posted: 2023-11-15

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