Channel:  Aligning Science Across Parkinson's (ASAP)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

318 Articles

Structural and biochemical insights into lipid transport by VPS13 proteins.
Adlakha, J., Hong, Z., Li, P., Reinisch, k. M.
10.1101/2022.03.11.484024 — Posted: 2022-03-12
In situ architecture of the lipid transport protein VPS13C at ER-lysosomes membrane contacts
Cai, S., Wu, Y., Guillen-Samander, A., Hancock-Cerutti, W. F., Liu, J., De Camilli, P.
10.1101/2022.03.08.482579 — Posted: 2022-03-08
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds
Saha, I., Yuste-Checa, P., da Silva Padilha, M., Guo, Q., Körner, R., Holthusen, H., Trinkaus, V. A., Dudanova, I., Fernandez-Busnadiego, R., Baumeister, W., Sanders, D. W., Gautam, S., Diamond, M. I., Hartl, F.-U., Hipp, M. S.
10.1101/2022.02.18.481043 — Posted: 2022-02-19
Highly efficient generation of isogenic pluripotent stem cell models using prime editing
Li, H., Busquets, O., Verma, Y., Syed, K. M., Kutnowski, N., Pangilinan, G. R., Gilbert, L., Bateup, H., Rio, D. C., Hockemeyer, D., Soldner, F.
10.1101/2022.02.15.480601 — Posted: 2022-02-15
Single-cell transcriptomic and proteomic analysis of Parkinson's disease Brains
Zhu, B., Park, J.-M., Coffey, S., Hsu, I.-U., Lam, T. T., Gopal, P. P., Ginsberg, S. D., Wang, J., Su, C., Zhao, H., Hafler, D. A., Chandra, S., Zhang, L.
10.1101/2022.02.14.480397 — Posted: 2022-02-14
Global Structure of the Intrinsically Disordered Protein Tau Emerges from its Local Structure
Stelzl, L. S., Pietrek, L. M., Holla, A., Oroz, J. S., Sikora, M., Köfinger, J., Schuler, B., Zweckstetter, M., Hummer, G.
10.1101/2021.11.23.469691 — Posted: 2022-02-14
Dopamine transporter and synaptic vesicle sorting defects initiate auxilin-linked Parkinson's disease
Vidyadhara, D. J., Somayaji, M., Wade, N., Yücel, B., Zhao, H., Shashaank, N., Ribaudo, J., Gupta, J., Lam, T. T., Sames, D., Greene, L. E., Sulzer, D. L., Chandra, S. S.
10.1101/2022.02.04.479203 — Posted: 2022-02-06
A mono- and intralink filter (mi-filter) to improve false-discovery rates in cross-linking mass spectrometry data
Chen, X., Sailer, C., Kammer, K.-M., Fuersch, J., Eisele, M. R., Sakata, E., Stengel, F.
10.1101/2022.02.03.478943 — Posted: 2022-02-03
Toward a phenome-wide view of Parkinson's disease
Olsen, A. L., Locascio, J. J., Tuncali, I., Laroussi, N., Abatzis, E., Kamenskaya, P., Kuras, Y., Yi, T., Videnovic, A., Hayes, M. T., Ho, G. P. H., Paulson, J., Khurana, V., Herrington, T. M., Hyman, B. T., Selkoe, D. J., Growdon, J. H., Gomperts, S. N., Riise, T., Schwarzschild, M. A., Hung, A. Y., Wills, A.-M., Scherzer, C. R.
10.1101/2022.02.01.22270276 — Posted: 2022-02-02
Structural basis for Parkinson's Disease-linked LRRK2's binding to microtubules
Snead, D. M., Matyszewski, M., Dickey, A. M., Lin, Y. X., Leschziner, A. E., Reck-Peterson, S. L.
10.1101/2022.01.21.477284 — Posted: 2022-01-22

RSS  Channel RSS