Channel:  Aligning Science Across Parkinson's (ASAP)

507 Articles

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Mitochondrial oxidant stress promotes alpha-synuclein aggregation and spreading in mice with mutated glucocerebrosidase
La Vitola, P., Szego, E. M., Pinto-Costa, R., Rollar, A., Harbachova, E., Schapira, A. H. V., Ulusoy, A., Di Monte, D. A.
10.1101/2024.06.13.598820 — Posted: 2024-06-13
Mitochondrial damage triggers concerted degradation of negative regulators of neuronal autophagy
Basak, B., Holzbaur, E. L. F.
10.1101/2024.06.12.598718 — Posted: 2024-06-13
Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain
Bagnoli, E., Lin, Y.-E., Burel, S., Jaimon, E., Antico, O., Themistokleous, C., Nikoloff, J., Morella, I., Watzlawik, J., Fiesel, F., Springer, W., Tonelli, F., Brooks, S., Dunnett, S., Brambilla, R., Alessi, D. R., Pfeffer, S. R., Muqit, M.
10.1101/2024.06.11.598416 — Posted: 2024-06-11
Impaired Functional Connectivity of Cortico-Amygdala Pathway Can Drive Social Behavior Deficits in Synucleinopathies
Zhou, W., Daniels, S., Singh, V., Menard, M., Galvis, M. E., Chu, H.-Y.
10.1101/2024.05.20.594995 — Posted: 2024-06-10
α-Synuclein Overexpression and the Microbiome Shape the Gut and Brain Metabolome in Mice
Morais, L. H., Boktor, J. C., MahmoudianDehkordi, S., Kaddurah-Daouk, R., Mazmanian, S. K.
10.1101/2024.06.07.597975 — Posted: 2024-06-10
LRRK2 mediates haloperidol-induced changes in indirect pathway striatal projection neurons
Chen, C., Masotti, M., Shepard, N., Promes, V., Tombesi, G., Arango, D., Manzoni, C., Greggio, E., Hilfiker, S., Kozorovitskiy, Y., Parisiadou, L.
10.1101/2024.06.06.597594 — Posted: 2024-06-08
Refinement of efficient encodings of movement in the dorsolateral striatum throughout learning
Jaidar, O., Albarran, E., Albarran, E., Wu, Y.-W., Ding, J. B.
10.1101/2024.06.06.596654 — Posted: 2024-06-06
A staged screening protocol identifies people with biomarkers related to neuronal alpha-synuclein disease
Brown, E. G., Chahine, L. M., Siderowf, A., Gochanour, C., Kurth, R., Marshall, M. J., Caspell-Garcia, C., Brumm, M. C., Coffey, C. S., Stanley, C. E., Korell, M., McMahon, B., Kuhl, M., Fabrizio, K., Heathers, L., Foroud, T. M., Concha-Marambio, L., Soto, C., Chowdhury, S., Simuni, T., Marek, K., Tanner, C. M., the Parkinson's Progression Markers Initiative
10.1101/2024.06.03.24308229 — Posted: 2024-06-04
The diversity of SNCA transcripts in neurons, and its impact on antisense oligonucleotide therapeutics
Evans, J. R., Gustavsson, E. K., Doykov, I., Murphy, D., Virdi, G., Lachica, J., Rontgen, A., Murtada, M. H., Pang, C. W., Macpherson, H., Wernick, A. I., Toomey, C. E., Athauda, D., Choi, M., Hardy, J., Wood, N. W., Vendruscolo, M., Mills, K., Heywood, W., Ryten, M., Gandhi, S.
10.1101/2024.05.30.596437 — Posted: 2024-05-31
Microbiome-based biomarkers to guide personalized microbiome-based therapies for Parkinson's disease
Payami, H., Sampson, T. R., Murchison, C. F., Wallen, Z. D.
10.1101/2024.04.03.24305273 — Posted: 2024-05-30

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