Channel:  Aligning Science Across Parkinson's (ASAP)

535 Articles

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The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds
Saha, I., Yuste-Checa, P., da Silva Padilha, M., Guo, Q., Körner, R., Holthusen, H., Trinkaus, V. A., Dudanova, I., Fernandez-Busnadiego, R., Baumeister, W., Sanders, D. W., Gautam, S., Diamond, M. I., Hartl, F.-U., Hipp, M. S.
10.1101/2022.02.18.481043 — Posted: 2022-02-19
Highly efficient generation of isogenic pluripotent stem cell models using prime editing
Li, H., Busquets, O., Verma, Y., Syed, K. M., Kutnowski, N., Pangilinan, G. R., Gilbert, L., Bateup, H., Rio, D. C., Hockemeyer, D., Soldner, F.
10.1101/2022.02.15.480601 — Posted: 2022-02-15
Single-cell transcriptomic and proteomic analysis of Parkinson's disease Brains
Zhu, B., Park, J.-M., Coffey, S., Hsu, I.-U., Lam, T. T., Gopal, P. P., Ginsberg, S. D., Wang, J., Su, C., Zhao, H., Hafler, D. A., Chandra, S., Zhang, L.
10.1101/2022.02.14.480397 — Posted: 2022-02-14
Dopamine transporter and synaptic vesicle sorting defects initiate auxilin-linked Parkinson's disease
Vidyadhara, D. J., Somayaji, M., Wade, N., Yücel, B., Zhao, H., Shashaank, N., Ribaudo, J., Gupta, J., Lam, T. T., Sames, D., Greene, L. E., Sulzer, D. L., Chandra, S. S.
10.1101/2022.02.04.479203 — Posted: 2022-02-06
A mono- and intralink filter (mi-filter) to improve false-discovery rates in cross-linking mass spectrometry data
Chen, X., Sailer, C., Kammer, K.-M., Fuersch, J., Eisele, M. R., Sakata, E., Stengel, F.
10.1101/2022.02.03.478943 — Posted: 2022-02-03
Structural basis for Parkinson's Disease-linked LRRK2's binding to microtubules
Snead, D. M., Matyszewski, M., Dickey, A. M., Lin, Y. X., Leschziner, A. E., Reck-Peterson, S. L.
10.1101/2022.01.21.477284 — Posted: 2022-01-22
Intravenous gene transfer throughout the brain of infant Old World primates using AAV
Chuapoco, M. R., Flytzanis, N., Goeden, N., Octeau, J. C., Roxas, K. M., Chan, K. Y., Scherrer, J., Winchester, J., Blackburn, R. J., Campos, L. J., Arokiaraj, C. M., Miles, T. F., Jang, M. J., Vendemiatti, J., Deverman, B. E., Pickel, J., Fox, A. S., Gradinaru, V.
10.1101/2022.01.08.475342 — Posted: 2022-01-09
Diversity in Parkinson's disease genetics research: current landscape and future directions
Schumacher-Schuh, A. F., Bieger, A., Okunoye, O., Mok, K., Lim, S.-Y., Bardien, S., Annuar, A. A., Lopes-Santos, B., Strelow, M. Z., Salama, M., Rao, S., Zewde, Y. Z., Dindayal, S., Azar, J., Kukkle, P. L., Rajan, R., Noyce, A. J., Okubadejo, N., Rizig, M., Lesage, S., Mata, I., Global Parkinson's Genetic Program (GP2)
10.1101/2021.12.07.21266995 — Posted: 2021-12-08
Transient dopamine neuron activity precedes and encodes the vigor of contralateral movements
Mendonca, M. D., Alves da Silva, J., Hernandez, L. F., Castela, I., Obeso, J., Costa, R. M.
10.1101/2021.04.20.440527 — Posted: 2021-12-02
Therapeutic Deep Brain Stimulation Disrupts Subthalamic Nucleus Activity Dynamics in Parkinsonian Mice
Schor, J. S., Gonzalez Montalvo, I., Spratt, P. W. E., Brakaj, R. J., Stansil, J. A., Bender, K. J., Nelson, A. B.
10.1101/2021.11.12.468404 — Posted: 2021-11-13

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