Channel:  Aligning Science Across Parkinson's (ASAP)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

335 Articles

Post-fibrillization nitration of alpha-synuclein abolishes its seeding activity and pathology formation in primary neurons and in vivo
Donzelli, S., OSullivan, S., Mahul-Mellier, A.-L., Ulusoy, A., Fusco, G., Kumar, S. T., Chiki, A., Burtscher, J., Boussouf, M. L. D., Rostami, I., De Simone, A. D. S., Di Monte, D. A., Lashuel, H. A.
10.1101/2023.03.24.534149 — Posted: 2023-03-25
Protein network analysis links the NSL complex to Parkinson's disease and mitochondrial biology
Kelly, K., Lewis, P., Plun-Favreau, H., Manzoni, C.
10.1101/2023.01.27.524249 — Posted: 2023-03-24
The annotation and function of the Parkinson's and Gaucher disease-linked gene GBA1 has been concealed by its protein-coding pseudogene GBAP1
Gustavsson, E. K., Sethi, S., Gao, Y., Brenton, J., Garcia Ruiz, S., Zhang, D., Garza, R., Reynolds, R. H., Evans, J. R., Chen, Z., Grant-Peters, M., MacPherson, H., Montgomery, K., Dore, R., Wernick, A. I., Arber, C., Wray, S., Gandhi, S., Esselborn, J., Blauwendraat, C., Douse, C. H., Adami, A., Atacho, D. A. M., Kouli, A., Quaegebeur, A., Barker, R. A., Englund, E., Platt, F. M., Jakobsson, J., Wood, N. W., Houlden, H., Saini, H., Bento, C. F., Hardy, J., Ryten, M.
10.1101/2022.10.21.513169 — Posted: 2023-03-21
State-dependent GABAergic regulation of striatal spiny projection neuron excitability
Day, M., Belal, M., Surmeier, C., Melendez-Zaidi, A., Tkatch, T., Clarke, V. R. J., Surmeier, D. J.
10.1101/2023.03.14.532627 — Posted: 2023-03-15
L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
Garza, R., Atacho, D., Adami, A., Gerdes, P., Vinod, M., Hsieh, P., Karlsson, O., Horvath, V., Johansson, P. A., Pandiloski, N., Matas, J., Quaegebeur, A., Kouli, A., Sharma, Y., Jonsson, M. E., Monni, E., Englund, E., Eichler, E. E., Gale Hammell, M., Barker, R. A., Kokaia, Z., Douse, C. H., Jakobsson, J.
10.1101/2023.03.04.531072 — Posted: 2023-03-06
Assessment of heterogeneity and disease onset in the Parkinson's Progression Markers Initiative (PPMI) cohort using the α-synuclein seed amplification assay: a cross-sectional study
Siderowf, A., Concha-Marambio, L., Lafontant, D.-E., Farris, C. M., Ma, Y., Urenia, P. A., Nguyen, H., Alcalay, R. N., Chahine, L. M., Foroud, T., Galasko, D., Kieburtz, K., Merchant, K., Mollenhauer, B., Poston, K. L., Seibyl, J., Simuni, T., Tanner, C. M., Weintraub, D., Videnovic, A., Choi, S. H., Kurth, R., Caspell-Garcia, C., Coffey, C. S., Frasier, M., Oliveiras, L. M. A., Hutten, S. J., Sherer, T., Marek, K., Soto, C.
10.1101/2023.02.27.23286156 — Posted: 2023-03-01
From Policy to Practice: Tracking an Open Science Funding Initiative
Ratan, K., Dumanis, S. B., McIntosh, S., Shah, H. V., Lewis, M., Vines, T. H., Schekman, R., Riley, E. A. U.
10.1101/2023.02.27.530238 — Posted: 2023-02-28
Genome-wide screen reveals Rab12 GTPase as a critical activator of pathogenic LRRK2 kinase
Dhekne, H. S., Tonelli, F., Yeshaw, W. M., Chiang, C. Y., Limouse, C., Jaimon, E., Purlyte, E., Alessi, D. R., Pfeffer, S. R.
10.1101/2023.02.17.529028 — Posted: 2023-02-18
Integrated single cell and unsupervised spatial transcriptomic analysis defines molecular anatomy of the human dorsolateral prefrontal cortex
Huuki-Myers, L. A., Spangler, A., Eagles, N. J., Montgomery, K. D., Kwon, S. H., Guo, B., Grant-Peters, M., Divecha, H. R., Tippani, M., Sriworarat, C., Nguyen, A. B., Ravichandran, P., Tran, M. N., Seyedian, A., PsychENCODE Consortium, , Hyde, T. M., Kleinman, J. E., Battle, A., Page, S. C., Ryten, M., Hicks, S. C., Martinowich, K., Collado-Torres, L., Maynard, K. R.
10.1101/2023.02.15.528722 — Posted: 2023-02-15
Adult-specific Reelin expression alters striatal neuronal organization. Implications for neuropsychiatric disorders.
Pardo, M., Gregorio, S., Montalban, E., Pujadas, L., Elias-Tersa, A., Masachs, N., Vilchez-Acosta, A., Parent, A., Auladell, C., Girault, J. A., Vila, M., Nairn, A. C., Manso, Y., Soriano, E.
10.1101/2023.01.21.525025 — Posted: 2023-01-22

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