Channel:  Aligning Science Across Parkinson's (ASAP)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

376 Articles

Understanding monogenic Parkinson's disease at a global scale
Junker, J., Lange, L. M., Vollstedt, E.-J., Roopnarain, K., Doquenia, M. L. M., Ahmad-Annuar, A., Avenali, M., Bardien, S., Bahr, N., Ellis, M., Galandra, C., Gasser, T., Heutink, P., Illarionova, A., Kanana, Y., Keller Sarmiento, I. J., Kumar, K. R., Lim, S.-Y., Madoev, H., Mata, I., Mencacci, N. E., Nalls, M. A., Padmanabhan, S., Shambetova, C., Solle, J., Tan, A.-H., Trinh, J., Valente, E. M., Singleton, A., Blauwendraat, C., Lohmann, K., Fang, Z.-H., Klein, C., the Global Parkinson's Genetics Program (GP2)
10.1101/2024.03.12.24304154 — Posted: 2024-04-09
Combined detrimental effect of male sex and GBA1 variants on cognitive decline in Parkinson's Disease
Caminiti, S. P., Avenali, M., Galli, A., Malito, R., Cuconato, G., Pilotto, A., Padovani, A., Blandini, F. P., Perani, D., Tassorelli, C., Valente, E. M.
10.1101/2024.04.02.24305191 — Posted: 2024-04-03
SARM1 activation induces reversible mitochondrial dysfunction and can be prevented in human neurons by antisense oligonucleotides
Loreto, A., Cramb, K. M. L., McDermott, L. A., Antoniou, C., Cirilli, I., Caiazza, M. C., Merlini, E., Arthur-Farra, P., Mock, E. D., Zhao, H. T., Bennett, D. L., Orsomando, G., Coleman, M. P., Wade-Martins, R.
10.1101/2024.04.02.587827 — Posted: 2024-04-03
Detecting rhythmic spiking through the power spectra of point process model residuals
Cox, K. M., Kase, D., Znati, T., Turner, R. S.
10.1101/2023.09.08.556120 — Posted: 2024-03-25
Comparison of Alternative pre-mRNA Splicing and Gene Expression Patterns in Midbrain Lineage Cells Carrying Familial Parkinson's Disease Mutations
Lee, Y. J., Syed, K., Busquets, O., Li, H., Dunnack, J., Sahagun, A., Bateup, H., Soldner, F., Hockemeyer, D., Rio, D.
10.1101/2024.02.28.582420 — Posted: 2024-03-12
Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies
Nazeen, S., Wang, X., Zielinski, D., Lam, I., Hallacli, E., Xu, P., Ethier, E., Strom, R., Zanella, C. A., Nithianandam, V., Ritter, D., Henderson, A., Saurat, N., Afroz, J., Nutter-Upham, A., Benyamini, H., Copty, J., Ravishankar, S., Morrow, A., Mitchel, J., Neavin, D., Gupta, R., Farbehi, N., Grundman, J., Myers, R. H., Scherzer, C. R., Trojanowski, J. Q., Van Deerlin, V. M., Cooper, A. A., Lee, E. B., Erlich, Y., Lindquist, S., Peng, J., Geschwind, D. H., Powell, J., Studer, L., Feany, M. B., Sunyaev, S. R., Khurana, V.
10.1101/2024.03.03.583145 — Posted: 2024-03-07
LRRK2 G2019S mutation suppresses differentiation of Th9 and Treg cells via JAK/STAT3
Zheng, N., Jaffery, R., Guerrero, A., Hou, J., Pan, Y., Zhou, F., Chen, S., Xu, C., Egan, N. A., Bohat, R., Chen, K., Schwarzschild, M. A., Chen, X., Peng, W.
10.1101/2024.02.28.582561 — Posted: 2024-03-03
Adoptive transfer of mitochondrial antigen-specific CD8+ T-cells in mice causes parkinsonism and compromises the dopamine system
Elemeery, M. N., Tchung, A., Boulet, S., Mukherjee, S., Giguere, N., Daudelin, J.-F., Hetu-Arbour, R., Matheoud, D., STRATTON, J. A., Labrecque, N., Trudeau, L.-E.
10.1101/2024.02.26.582098 — Posted: 2024-02-28
Comparative study of enriched dopaminergic neurons from siblings with Gaucher disease discordant for parkinsonism
Hertz, E., Perez, G., Hao, Y., Rytel, K., Ma, C., Kirby, M., Anderson, S., Wincovitch, S., Andersh, K., Ahfeldt, T., Blanchard, J., Qi, Y. A., Lopez, G., Tayebi, N., Sidransky, E., Chen, Y.
10.1101/2024.02.25.581985 — Posted: 2024-02-28
GLP-1 receptor agonism ameliorates Parkinsons disease through modulation of neuronal insulin signalling and glial suppression
Athauda, D., Evans, J. R., Sanchez, L., Virdi, G., Lopez Garcia, P., Wernick, A., Wagen, A., D'Sa, K., Lachica, J., Strohbuecker, S., Vecchi, G., Leighton, C., Saleeb, R. S., OShaughnessy, J., Toomey, C., Vijiaratnam, N., Girges, C., Li, Y., Mustapic, M., Ismail, K., Davies, M., Kapogiannis, D., Choi, M. L., Ryten, M., Horrocks, M. H., Greig, N. H., Foltynie, T., Gandhi, S.
10.1101/2024.02.28.582460 — Posted: 2024-02-28

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