Channel:  Aligning Science Across Parkinson's (ASAP)

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Subcellular proteomics of dopamine neurons in the mouse brain reveals axonal enrichment of proteins encoded by Parkinson's disease-linked genes
Hobson, B. D., Choi, S. J., Soni, R. K., Sulzer, D., Sims, P. A.
10.1101/2021.06.01.446584 — Posted: 2021-06-09
ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling
Hancock-Cerutti, W. F., Wu, Z., Tharkeshwar, A. K., Ferguson, S. M., Shadel, G. S., De Camilli, P.
10.1101/2021.06.08.447593 — Posted: 2021-06-08
HyDrop: droplet-based scATAC-seq and scRNA-seq using dissolvable hydrogel beads
De Rop, F. V., Ismail, J. N., Bravo Gonzalez-Blas, C., Hulselmans, G. J., Flerin, C. C., Janssens, J., Theunis, K., Christiaens, V. M., Wouters, J., Marcassa, G., de Wit, J., Poovathingal, S., Aerts, S.
10.1101/2021.06.04.447104 — Posted: 2021-06-06
Transcriptional analysis of peripheral memory T cells reveals Parkinson's disease-specific gene signatures
Dhanwani, R., Rodrigues Lima-Junior, J., Sethi, A., Pham, J., Williams, G., Frazier, A., Xu, Y., Amara, A. W., Standaert, D. G., Goldman, J. G., Litvan, I., Alcalay, R. N., Peters, B., Sulzer, D., Lindestam Arlehamn, C. S., Sette, A.
10.1101/2021.05.28.446215 — Posted: 2021-05-29
Structural Basis for Membrane Recruitment of ATG16L1 by WIPI2 in Autophagy
Strong, L. M., Chang, C., Boecker, A., Flower, T. G., Buffalo, C. Z., Ren, X., Stavoe, A. K., Holzbaur, E. L. F., Hurley, J. H.
10.1101/2021.05.14.444175 — Posted: 2021-05-14
ALS and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy
Harding, O., Evans, C. S., Ye, J., Cheung, J., Maniatis, T., Holzbaur, E. L. F.
10.1101/2021.04.12.439050 — Posted: 2021-04-12
Global ubiquitylation analysis of mitochondria in primary neurons identifies physiological Parkin targets following activation of PINK1
Antico, O., Ordureau, A., Stevens, M., Singh, F., Gierlinski, M., Barini, E., Rickwood, M., Prescott, A. R., Toth, R., Ganley, I., Harper, W., Muqit, M.
10.1101/2021.04.01.438131 — Posted: 2021-04-01
Multi-Modality Machine Learning Predicting Parkinsons Disease
Makarious, M. B., Leonard, H. L., Vitale, D., Iwaki, H., Sargent, L., Dadu, A., Violich, I., Hutchins, E., Saffo, D., Bandres-Ciga, S., Kim, J. J., Song, Y., Bookman, M., Nojopranoto, W., Campbell, R. H., Hashemi, S. H., Botia, J. A., Carter, J. F., Maleknia, M., Craig, D. W., Keuren-Jensen, K. V., Morris, H. R., Hardy, J. A., Blauwendraat, C., Singleton, A. B., Faghri, F., Nalls, M. A., Accelerating Medicines Program - Parkinsons Disease (AMP PD), , Global Parkinsons Genetics Program (GP2)
10.1101/2021.03.05.434104 — Posted: 2021-03-07
Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain
Khan, S. S., Sobu, Y., Dhekne, H. S., Tonelli, F., Berndsen, K., Alessi, D. R., Pfeffer, S. R.
10.1101/2021.03.02.433576 — Posted: 2021-03-02
Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias
Vavouraki, N., Tomkins, J. E., Kara, E., Houlden, H., Hardy, J., Tindall, M. J., Lewis, P. A., Manzoni, C.
10.1101/2021.01.14.425874 — Posted: 2021-01-16

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